Journals / International Journal of Applied Mathematics Electronics and Computers / 2016 / Special Issue (2016)

Monitoring of Anxiety-Like Behaviors on Rats with Video Tracking Technology

Pages
161–164
Publication Date
2016-12-01
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In addition, the visual tracking results demonstrate that video tracking system provides an accurate monitoring of rat’s behavior.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Artificial sweeteners like MSG (Mono Sodium Glutamate) model has been used anxiety-like behaviors on rats.
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Key Findings & Data:The tracking of rat’s movements has broad applicability to questions in anxiety-like behaviors with different doses MSG injections (50 mg/kg/day, 100 mg/kg/day and 200 mg/kg/day) to rats.
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Conclusion & Impact:In addition, the visual tracking results demonstrate that video tracking system provides an accurate monitoring of rat’s behavior.
🔬Design:Modeling & Simulation
📍Scope:Comprehensive Sample
⚙️Variables:Rat · locomotor activity · anxiety-like behaviors

Abstract

Artificial sweeteners like MSG (Mono Sodium Glutamate) model has been used anxiety-like behaviors on rats. The tracking of rat’s movements has broad applicability to questions in anxiety-like behaviors with different doses MSG injections (50 mg/kg/day, 100 mg/kg/day and 200 mg/kg/day) to rats. In this paper, in order to measure three types locomotor activity (line crossing, rearing, grooming), a video tracking software is used. The advantage of this type of tracking software is that it provides to give locomotor activity of rats in real-time. The experimental results obtained in this study have shown that learning and memorial functions negatively affected in the brains of the rats an anxiety-like model. In addition, the visual tracking results demonstrate that video tracking system provides an accurate monitoring of rat’s behavior.

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Cite This Article

KARDEŞLER, A. Ç., ÇETİN, M., BEYHAN, S. (2016). Monitoring of Anxiety-Like Behaviors on Rats with Video Tracking Technology. International Journal of Applied Mathematics Electronics and Computers, Special Issue (2016), 161–164. https://ajindex.com/articles/258175

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References (14)

  1. S. Vinogradov, et al. Is serum brain-derived neurotrophic factor a biomarker for cognitive enhancement in schizophrenia? Biol Psychiatry.; vol. 66, pp. 549-553, 2009
  2. P. Ma, X. Liu, J. Wu, B. Yan, Y. Zhang, Y. Lu, Y. Wu, C. Liu, J. Guo, E. Nanberg, C.G. Bornehag, X. Yang. Cognitive deficits and anxiety induced by diisononyl phthalatein mice and the neuroprotective effects of melatonin, Nature. Vol. 5, pp. e14676, 2015
  3. M. Dubovicky, D. Tokarev, I. Skultetyova, D. Jezova. Changes of exploratory behavior and its habituation in rats neonatally treated with monosodium glutamate, Pharmacol Biochem Behav, vol, 56, pp. 565-569, 1997
  4. Z. Hlinak, D. Gandalovicova & I. Krejci. Behavioral deficits in adult rats treated neonatally with glutamate, Neurotoxicol Teratol, vol. 27, pp. 465–473, 2005
  5. N. Enginar, I. Hatipoglu, ˘ M. Firtina, Evaluation of the acute effects of amitriptyline and fluoxetine on anxiety using grooming analysis algorithm in rats, Pharmacol. Biochem. Behav. Vol. 89, pp. 450–455, 2008
  6. T.S. Perrot-Sinal, A. Gregus, D. Boudreau, L.E. Kalynchuk, Sex and repeated restraint stress interact to affect cat odor-induced defensive behavior in adult rats, Brain Res., vol. 1027, pp. 161–172, 2004
  7. A. Takeda, H. Tamano, F. Kan, H. Itoh, N. Oku, Anxiety-like behavior of young rats after 2-week zinc deprivation, Behav. Brain Res., vol. 177, pp. 1–6, 2007
  8. O.J. Onaolapo, A.Y. Onaolapo, M.A. Akanmu, G. Olayiwola, Foraging enrichment modulates open field response to monosodium glutamate in mice. Annals of neurosciences, vol. 22.3, pp. 162, 2015
  9. P. Muigg, S. Scheiber, P. Salchner, M. Bunck, R. Landgraf, N. Singewald, Differential stress-induced neuronal activation patterns in mouse lines selectively bred for high, normal or low anxiety, PLoS One vol. 4, e5346, 2009
  10. RJ. Beninger, TA. Cooper, EJ. Mazurski, “Automating the measurement of locomotor activity”, Neurobehav Toxicol Teratol, vol. 7, pp. 79–85, 1985
  11. RL. Clarke, RF. Smith, DR. Justesen, “An infrared device for detecting locomotor activity”, Behav Res Methods Instrum Comput, vol. 17, pp. 519–525, 1985
  12. E. Robles, “A method to analyze the spatial distribution of behavior”, Behav Res Methods Instrum Comput, vol. 22, pp. 540–549, 1990
  13. MH. Teicher, SL. Andersen, P. Wallace, DA. Klein, J. Hostetter, Development of an affordable hi-resolution activity monitor system for laboratory animals, Pharmacol Biochem Behav, vol. 54, pp. 479–483, 1996
  14. HA. Van