The effect which we observed applying the lead nitrate and mercury chloride together, was more greater than when we used them alone.
📌 3 Key Takeaways
🎯
Objective & Hypothesis:The present study was undertaken to evaluate the effects of lead nitrate and mercury chloride in brain tissues of Wistar rats.
📊
Key Findings & Data:Mercury chloride (0.02 mg/kg bw) and lead nitrate (45 mg/kg bw) were administered orally for 28 days rats.
💡
Conclusion & Impact:The effect which we observed applying the lead nitrate and mercury chloride together, was more greater than when we used them alone.
The present study was undertaken to evaluate the effects of lead nitrate and mercury chloride in brain tissues of Wistar rats. Mercury chloride (0.02 mg/kg bw) and lead nitrate (45 mg/kg bw) were administered orally for 28 days rats. The mercury chloride and lead nitrate treated animals were exhibited a significant inhibition of superoxide dismutase, catalase, glutation peroxidase and glutathione-S-transferase activities and increasing of malondialdehyde levels. In our present study mercury chloride caused more harmful effects than lead nitrate. The effect which we observed applying the lead nitrate and mercury chloride together, was more greater than when we used them alone.
BAŞ, H., KALENDER, S., KARABODUK, H., APAYDIN, F. (2015). The Effects on Antioxidant Enzyme Systems in Rat Brain Tissues of Lead Nitrate and Mercury Chloride. Gazi University Journal of Science, Cilt: 28 - Sayı: 2, 169–174. https://ajindex.com/articles/254907
Latif, R., Malek, M., Mirmonsef, H., “Cadmium and lead accumulation in three endogeic earthworm species”, Bull. Environ. Contam. Toxicol. 90: 456–459 (2013). [2] “Embryotoxicity hazard assessment of cadmium and L., Bremer, S., arsenic compounds using embryonic stem cells”, Toxicology 252: 118–122 (2008).
Garcia-Nino, W.R., Pedraza-Chaverri, J., “Protective effect of curcumin against heavy metals-induced liver damage”, Food Chem. Toxicol. 69: 182–201 (2014).
Alissa, E., Ferns, G., “Heavy metal poisoning and cardiovascular disease”, J. Toxicol. 2011: 1–21 (2011).
Zbakh, H., Abbassi, A.E., “Potential use of olive mill wastewater in the preparation of functional beverages: a review”, J. Funct. Food 4: 450–458 (2012).
Nevin, R., “Understanding international crime trends: the legacy of preschool lead exposure”, Environ. Res. 104: 315–336 (2007). [7] Dewanjee, Gangopadhyay, M., “Toxic effects of lead exposure in Wistar rats: involvement of oxidative stress and the beneficial role of edible jute (Corchorus olitorius) leaves”, Food Chem. Toxicol. 55: 78–91 (2013).
S., Piccoli, C., D'Aprile, A., Scrima, R., Ambrosi, L., Zefferino, R., Capitanio, N., “Subcytotoxic mercury chloride communication by a redox- and phosphorylation- mediated mechanism”, Free Radical Biol. Med. 52: 916– 927 (2012). junction intercellular [9] Zhang, F.S., Nriagu, J.O., Itoh, H., “Mercury removal from water using activated carbons derived from organic sewage sludge”, Water Res. 39: 389–395 (2005).
Yavuz, H., Denizli, A., Gungunes, H., Safarikova, M., Safarik, I., “Biosorption of mercury on magnetically modified yeast cells”, Sep. Purif. Technol. 52: 253–260 (2006).
Inbaraj, B.S., Wang, J.S., Lu, J.F., Siao, F.Y., Chen, B.H., “Adsorption of toxic mercury(II) by an extracellular Bioresource Technol. 100(1): 200-207 (2009). poly(c-glutamic acid)”, [12] Baş, H., Kalender, S., Pandır, D., “In vitro effects of quercetin on oxidative stress mediated in human erythrocytes by benzoic acid and citric acid”, Folia Biol- Krakow 62(1): 59-66 (2014).
Liu, C., Ma, J., Sun, Y., “Quercetin protects the rat kidney against oxidative stress mediated DNA damage and apoptosis induced by lead”, Environ. Toxicol. Pharmacol. 30: 264-271 (2010).
Yole, M., Wickstrom, M., Blakley, B., “Cell death and cytotoxic effects in YAC-1 lymphoma cells following exposure to various forms of mercury”, Toxicology 231: 40-57 (2007).
Sharma, V., Sharma, A., Kansal, L., “The effect of oral administration of Allium sativum extracts on l