Journals / Turkish Journal of Medical Sciences / 2014 / Cilt: 44 - Sayı: 3

Relation of age and sex with carotid intima media thickness in healthy children

Pages
422–426
Publication Date
2014-05-18
DOI
—
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Conclusion: Our results suggest that age-related physiologic thickening of the carotid artery intima-media occurs not only in adults but also in children and that sex is not a factor for cIMT differences in childhood.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:To investigate the age- and sex-associated carotid intima media thickness (cIMT) changes in healthy children to determine the age- and sex-specific normal range of values for childhood.
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Key Findings & Data:Materials and methods: This study examined 91 healthy school-age children aged 7-15 years prospectively.
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Conclusion & Impact:Conclusion: Our results suggest that age-related physiologic thickening of the carotid artery intima-media occurs not only in adults but also in children and that sex is not a factor for cIMT differences in childhood.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Key words: Carotid artery · intima-media thickness · ultrasonography

Abstract

To investigate the age- and sex-associated carotid intima media thickness (cIMT) changes in healthy children to determine the age- and sex-specific normal range of values for childhood. Materials and methods: This study examined 91 healthy school-age children aged 7-15 years prospectively. Standardized sonographic cIMT measurements and analyses were performed. Body mass index and blood pressure were obtained, and atherosclerotic risk factors were investigated. Age-and sex-specific cIMT measurements for different age groups were calculated and the relation with sex was investigated. Results: Regarding the total study group, mean cIMT measurements for age groups 7-9, 10-12, and 13-15 years were 4.1 ± 0.5 mm, 4.4 ± 0.6 mm, and 4.6 ± 0.4 mm, respectively. cIMT did not differ between boys and girls in the same age group. Age related analyses showed significant variations among the age groups with positive correlation between cIMT and age. Conclusion: Our results suggest that age-related physiologic thickening of the carotid artery intima-media occurs not only in adults but also in children and that sex is not a factor for cIMT differences in childhood.

Özet

To investigate the age- and sex-associated carotid intima media thickness (cIMT) changes in healthy children to determine the age- and sex-specific normal range of values for childhood. Materials and methods: This study examined 91 healthy school-age children aged 7-15 years prospectively. Standardized sonographic cIMT measurements and analyses were performed. Body mass index and blood pressure were obtained, and atherosclerotic risk factors were investigated. Age-and sex-specific cIMT measurements for different age groups were calculated and the relation with sex was investigated. Results: Regarding the total study group, mean cIMT measurements for age groups 7-9, 10-12, and 13-15 years were 4.1 ± 0.5 mm, 4.4 ± 0.6 mm, and 4.6 ± 0.4 mm, respectively. cIMT did not differ between boys and girls in the same age group. Age related analyses showed significant variations among the age groups with positive correlation between cIMT and age. Conclusion: Our results suggest that age-related physiologic thickening of the carotid artery intima-media occurs not only in adults but also in children and that sex is not a factor for cIMT differences in childhood.

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Cite This Article

KOÇYİĞİT, A., DOĞAN, M., YILMAZ, İ., ÇAĞLAR, M., HATİPOĞLU, C., KOÇYİĞİT, F., HEREK, D., KARABULUT, N. (2014). Relation of age and sex with carotid intima media thickness in healthy children. Turkish Journal of Medical Sciences, Cilt: 44 - Sayı: 3, 422–426. https://ajindex.com/articles/228094

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References (10)

  1. Berenson GS, Srinivasan SR, Bao W, Newman WP 3rd, Tracy RE, Wattigney WA. Association between multiple cardiovascular risk factors and atherosclerosis in children and young adults. The Bogalusa Heart Study. N Engl J Med 1998; 338: 1650–1656.
  2. Itagi V, Patil R. Obesity in children and adolescents and its relationship with hypertension. Turk J Med Sci 2011; 41: 259– 2 Demircioğlu F, Koçyiğit A, Arslan N, Cakmakçi H, Hizli S, Sedat AT. Intima-media thickness of carotid artery and susceptibility to atherosclerosis in obese children with nonalcoholic fatty liver disease. J Pediatr Gastroenterol Nutr 2008; 47: 68–75.
  3. Chambless LE, Heiss G, Folsom AR, Rosamond W, Szklo M, Sharrett AR, Clegg LX. Association of coronary heart disease incidence with carotid arterial wall thickness and major cardiovascular risk factors: the atherosclerosis risk in communities (ARIC) study, 1987–1993. Am J Epidemiol 1997; 146: 483–494.
  4. Schmidt-Trucksass A, Grathwohl D, Schmid A, Boragk R, Upmeier C, Keul J, Huonker M. Structural, functional and hemodynamic changes of the common carotid artery with age in male subjects. Arterioscler Thromb Vasc Biol 1999; 19: 1091–1097.
  5. Lakatta EG, Levy D. Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part I: aging arteries: a “set up” for vascular disease. Circulation 2003; 107: 139–146.
  6. Ishizu T, Ishimitsu T, Yanagi H, Seo Y, Obara K, Moriyama N, Watanabe S, Yamaguchi I. Effect of age on carotid arterial intima-media thickness in childhood. Heart Vessels 2004; 19: 189–195.
  7. Böhm B, Hartmann K, Buck M, Oberhoffer R. Sex differences of carotid intima-media thickness in healthy children and adolescents. Atherosclerosis 2009; 206: 458–463.
  8. Lurbe E, Cifkova R, Cruickshank JK, Dillon MJ, Ferreira I, Invitti C, Kuznetsova T, Laurent S, Mancia G, Morales-Olivas F et al. Management of high blood pressure in children and adolescents: recommendations of the European Society of Hypertension. J Hypertens 2009; 27: 1719–1742.
  9. Yilmaz D, Inan G, Karakas S, Buyukozturk-Karul A, Sonmez F. obesity and its diagnostic methods in Turkish children. EAJM 2012; 44: 94 –98. Sass C, Herbeth B, Chapet O, Siest G, Visvikis S, Zannad F. Intima-media thickness and diameter of carotid and femoral arteries in children. adolescents and adults from the Stanislas cohort: effect of age, sex, anthropometry and blood pressure. J Hypertens 1998; 16: 1593–1602.
  10. Adolphe A, Cook LS, Huang X. A cross-sectional study of intima-media thickness, ethnicity, me