Effects of intraabdominal pressure on mean platelet volume during laparoscopic cholecystectomy

Conclusion: Increasing MPV values may reflect increased intraabdominal pressures, which may have a clinical implementation in intraabdominal hypertension.

📌 3 Key Takeaways

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Objective & Hypothesis:Intraabdominal hypertension is a common occurrence, especially in intensive care unit patients, and it has high mortality and morbidity rates.

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Key Findings & Data:The study included 103 patients who met the inclusion criteria.

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Conclusion & Impact:Conclusion: Increasing MPV values may reflect increased intraabdominal pressures, which may have a clinical implementation in intraabdominal hypertension.

🔬Design:Modeling & Simulation

📍Scope:Comprehensive Sample

⚙️Variables:Key words: Mean platelet volume · intraabdominal hypertension · pneumoperitoneum

Abstract

Intraabdominal hypertension is a common occurrence, especially in intensive care unit patients, and it has high mortality and morbidity rates. The onset is commonly insidious and the poor prognosis is attributed to the long delay in diagnosis. Unfortunately, diagnosis is often delayed until loss of function in the affected tissues has already occurred. The aim of this study was to determine the predictive value of mean platelet volume (MPV) in assessing the risk of intraabdominal hypertension. Materials and methods: Pneumoperitoneum during elective laparoscopic cholecystectomy was used as a model for intraabdominal hypertension. The study included 103 patients who met the inclusion criteria. MPV evaluations were made at 3 distinct times during laparoscopic cholecystectomy based on the actual intraabdominal pressure. Results: MPV values during preinsufflation, insufflation, and desufflation were 8.483 fL (range: 6.7 to 11.1), 8.901 fL (range: 6.8 to 11.9), and 8.538 fL (range: 5.8 to 10.9), respectively. A statistically significant increase in MPV values was found during high intraabdominal pressures (P < 0.001). A significant decrease in MPV values was also detected with desufflation (P < 0.001). Conclusion: Increasing MPV values may reflect increased intraabdominal pressures, which may have a clinical implementation in intraabdominal hypertension.

Özet

Intraabdominal hypertension is a common occurrence, especially in intensive care unit patients, and it has high mortality and morbidity rates. The onset is commonly insidious and the poor prognosis is attributed to the long delay in diagnosis. Unfortunately, diagnosis is often delayed until loss of function in the affected tissues has already occurred. The aim of this study was to determine the predictive value of mean platelet volume (MPV) in assessing the risk of intraabdominal hypertension. Materials and methods: Pneumoperitoneum during elective laparoscopic cholecystectomy was used as a model for intraabdominal hypertension. The study included 103 patients who met the inclusion criteria. MPV evaluations were made at 3 distinct times during laparoscopic cholecystectomy based on the actual intraabdominal pressure. Results: MPV values during preinsufflation, insufflation, and desufflation were 8.483 fL (range: 6.7 to 11.1), 8.901 fL (range: 6.8 to 11.9), and 8.538 fL (range: 5.8 to 10.9), respectively. A statistically significant increase in MPV values was found during high intraabdominal pressures (P < 0.001). A significant decrease in MPV values was also detected with desufflation (P < 0.001). Conclusion: Increasing MPV values may reflect increased intraabdominal pressures, which may have a clinical implementation in intraabdominal hypertension.

Keywords

Key words: Mean platelet volume intraabdominal hypertension pneumoperitoneum

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Cite This Article

CELEP, R. B., KAHRAMANCA, Ş., ÖZSOY, M., AZILI, C., ÇETİNKÜNAR, S., HASDEMİR, A. O., GÜZEL, H., ÖZGEHAN, G., ÇOLHAN, İ., KÜÇÜKPINAR, T. H. (2014). Effects of intraabdominal pressure on mean platelet volume during laparoscopic cholecystectomy. Turkish Journal of Medical Sciences, Cilt: 44 - Sayı: 3, 360–364. https://ajindex.com/articles/228083

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