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Journals / GORM:Gynecology Obstetrics & Reproductive Medicine / 2008 / Cilt: 14 - Sayı: 3

Gestasyonel trombositopeni preeklampsi/HELLP sendromu ve immün trombositopenik purpuranın neden olduğu orta ve şiddetli trombositopenilerde maternal ve fetal sonuçların karşılaştırılması

A comparison of maternal and fetal outcomes of pregnancies complicated by moderate to severe thrombocytopenia caused by gestational thrombocytopenia preeclampsia / hellp syndrome and immune thrombocytopenic purpura

Suna ÖZDEMİR
HÜSEYİN GÖRKEMLİ
Ali ACAR
Çetin ÇELİK
Erkan KAYIKÇIOĞLU
Pages
154–158
DOI
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CONCLUSION: The thrombocytopenia with preeclampsia/HELLP syndrome had less favorable obstetric and fetal outcomes.

📌 3 Key Takeaways

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Objective & Hypothesis:OBJECTIVE: Aim of this study was to compare obstetric risk factors and complications, and outcomes of pregnancies associated with moderate to severe thrombocytopenia caused by gestational thrombocytopenia (GT), preeclampsia/HELLP syndrome, and immune thrombocytopenic purpura (ITP).
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Key Findings & Data:STUDY DESIGN: The study was composed of 135 women with a platelet count below 100.000/mm3.
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Conclusion & Impact:CONCLUSION: The thrombocytopenia with preeclampsia/HELLP syndrome had less favorable obstetric and fetal outcomes.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

OBJECTIVE: Aim of this study was to compare obstetric risk factors and complications, and outcomes of pregnancies associated with moderate to severe thrombocytopenia caused by gestational thrombocytopenia (GT), preeclampsia/HELLP syndrome, and immune thrombocytopenic purpura (ITP). STUDY DESIGN: The study was composed of 135 women with a platelet count below 100.000/mm3. The characteristics and clinical details of all women and neonatal were recorded during their hospital course. RESULTS: The ratio of severe thrombocytopenia was observed significantly lower in GT group compared with preeclampsia / HELLP syndrome and ITP groups. Higher rates of oligohydroamnios, IUGR, and placental abruption were found among patients in preeclampsia+HELLP syndrome group. The rates of Apgar scores (<7) at 1 and 5 min, pH values (<7,2), and amniotic fluid with meconium were higher in preeclampsia / HELLP syndrome group. Neonatal thrombocytopenia was recorded in a total of 5 infants. CONCLUSION: The thrombocytopenia with preeclampsia/HELLP syndrome had less favorable obstetric and fetal outcomes.

Özet

Bu çalışmada gestasyonel trombositopeni (GT), preeklamp-si/HELLP sendromu ve immün trombositopenik purpuranm neden olduğu orta ve şiddetli trombositopenilerde obstetrik risk faktörlerini, komplikasyonlarını ve gebelik sonuçlarının karşılaştırılması amaçlandı. Çalışmaya trombosit sayısı 100.000/mm3'den düşük olan 135 kadın alındı. Tanılar Hematoloji laboratuvarı tarafından konuldu. Olguların ve yeni doğanların hastane seyirlerindeki klinik özellikleri kaydedildi. Şiddetli trombositopeni GT grubunda diğer iki gruba göre daha düşük gözlendi. Preeklampsi/HELLP sendromlularda oligo-hidramnios, intrauterin gelişme geriliği ve ablatio plasenta yüksek oranlarda saptandı. Bir ve 5. dakikada Apgar skor oranları (<7), pH değerleri (<7,2) ve mekonyumlu amniyotik sıvı oranları preeklampsi/HELLP sendromlularda daha yüksekti. Neonatal trombositopeni 5 yeni doğanda tespit edildi. Sonuç olarak preeklampsi/HELLP sendromunun eşlik ettiği trombositopenili olgular, obstetrik ve fetal sonuçlar açısından en olumsuz grup olarak saptandı.

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Cite This Article

ÖZDEMİR, S., GÖRKEMLİ, H., ACAR, A., ÇELİK, Ç., KAYIKÇIOĞLU, E. (2008). Gestasyonel trombositopeni preeklampsi/HELLP sendromu ve immün trombositopenik purpuranın neden olduğu orta ve şiddetli trombositopenilerde maternal ve fetal sonuçların karşılaştırılması. GORM:Gynecology Obstetrics & Reproductive Medicine, Cilt: 14 - Sayı: 3, 154–158. https://ajindex.com/articles/227716

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