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Journals / GORM:Gynecology Obstetrics & Reproductive Medicine / 2008 / Cilt: 14 - Sayı: 3

Surrenal bez zona fasikülata tabakasının gebe sıçanlarda ultrastruktür değerlendirmesi

The ultrastructure of the zona fasciculata layer of suprarenal gland during pregnancy

Özgür EROĞLU
Neşe LORTLAR
Sevtap KILIÇ
M.Tahir HATİPOĞLU
Suna ÖMEROĞLU
Pages
140–144
DOI
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CONCLUSION: In conclusion, with the increased estrogen hormone of pregnancy, various structural changes were observed in the cortex of suprarenal glands as related to mutual interaction among secreted hormones from the suprarenal glands, hypophysis and placenta.

📌 3 Key Takeaways

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Objective & Hypothesis:OBJECTIVE: Increased estrogen levels affect the suprarenal gland cortex, thus raising the adrenocorticotropic hormone (ACTH) during pregnancy.
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Key Findings & Data:STUDY DESIGN: The suprarenal glands of 6-day, 12-day and 18-day pregnant rats were removed and compared with those of the control group under electron microscope.
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Conclusion & Impact:CONCLUSION: In conclusion, with the increased estrogen hormone of pregnancy, various structural changes were observed in the cortex of suprarenal glands as related to mutual interaction among secreted hormones from the suprarenal glands, hypophysis and placenta.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

OBJECTIVE: Increased estrogen levels affect the suprarenal gland cortex, thus raising the adrenocorticotropic hormone (ACTH) during pregnancy. This study aimed to examine possible structural changes in the suprarenal gland cortex in relation to the hormonal fluctuations during pregnancy. STUDY DESIGN: The suprarenal glands of 6-day, 12-day and 18-day pregnant rats were removed and compared with those of the control group under electron microscope. RESULTS: Lipid droplets in zona fasciculata cells were observed to increase significantly in number and volume, enlarged mitochondria, active Golgi region in comparison to the control groups on 6th and 12th days of pregnancy. On day 18 were observed to lipid droplets were seen to decrease and similar characteristics with the control group. CONCLUSION: In conclusion, with the increased estrogen hormone of pregnancy, various structural changes were observed in the cortex of suprarenal glands as related to mutual interaction among secreted hormones from the suprarenal glands, hypophysis and placenta.

Özet

Gebelik boyunca artan östrogen surrenal bez korteksini ve adrenocorticotropic hormon (ACTH) düzeylerini etkiler.Bu çalışmanın amacı gebelik boyunca hormonal dalgalanmalara bağlı olası surrenal bezde oluşabilen olası yapısal değişiklikleri araştırmayı hedeflemiştir.Surrenal bez gebeliğin 6. 12. 18. günlerinde dokudan ayrıldı electron mikroskopik değerlendirmeler kontrol grubuyla karşılaştırıldı.Gebe farelerin 6. ve 12. gün değerlendirmelerinde kontrol grubuna göre zona fasikülatalarında sayı ve volümleri artmış lipid dropletleri, mitokondrodionlarında genişleme ve aktive golgi aygıtları izlendi.gebeliğin 18. gününde lipid dropletlerinde azalma ve kontrolle benzer karakteristikler izlendi.Sonuç olarak gebeliğin artırdığı östrogen hormonu ile hipofiz, plesenta,surrenal bezden salınan hormonlar arasındaki ilişki sebebiyle surrenal bez kortexinde çeşitli yapısal değişklikler izlenmektedir.

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Cite This Article

EROĞLU, Ö., LORTLAR, N., KILIÇ, S., HATİPOĞLU, M., ÖMEROĞLU, S. (2008). Surrenal bez zona fasikülata tabakasının gebe sıçanlarda ultrastruktür değerlendirmesi. GORM:Gynecology Obstetrics & Reproductive Medicine, Cilt: 14 - Sayı: 3, 140–144. https://ajindex.com/articles/227715

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References (1)

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