Journals / GORM:Gynecology Obstetrics & Reproductive Medicine / 2005 / Cilt: 11 - Sayı: 3

Successful treatment with intraamniotic methotrexate injections in cervical pregnancies from IVF-ICSI cycles

Pages
211–214
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The major advantages of local injections of methotrexate into the amniotic cavity are direct organ-targeted effect of both surgical procedure and medical therapy.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Cervical pregnancy is a life threatening disorder which has an incidence of 1/1000 to 1/18000 live births.
📊
Key Findings & Data:Incidence of cervical pregnancy has increased recently due to use of assisted reproductive techniques for infertility.
💡
Conclusion & Impact:The major advantages of local injections of methotrexate into the amniotic cavity are direct organ-targeted effect of both surgical procedure and medical therapy.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Methotreksat · Gebelik komplikasyonları · Kısırlık

Özet

Cervical pregnancy is a life threatening disorder which has an incidence of 1/1000 to 1/18000 live births. Incidence of cervical pregnancy has increased recently due to use of assisted reproductive techniques for infertility. The underlying mechanisms for ectopic pregnancies in IVF cycles without absolute risks such as pelvic inflammatory disease, curettage and intrauterine device are unknown.Two cases of cervical pregnancy in IVF-ICSI cycles were treated successfully by intraamniotic injections of methotrexate in three months.Alterations in the normal contraction patterns of the uterus may result with expulsion of the embryos into the cervix during pregnancy. Slow progression of the oocytes and discordance between the embryos and the endometrium may be the etiology of abnormal uterine contractions leading to fundo-cervical contractions in the early luteal phase. The major advantages of local injections of methotrexate into the amniotic cavity are direct organ-targeted effect of both surgical procedure and medical therapy.

🔖

Cite This Article

ÖNALAN, G., ÖNALAN, R., SELAM, F. B., PABUÇCU, R. (2005). Successful treatment with intraamniotic methotrexate injections in cervical pregnancies from IVF-ICSI cycles. GORM:Gynecology Obstetrics & Reproductive Medicine, Cilt: 11 - Sayı: 3, 211–214. https://ajindex.com/articles/227322

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (9)

  1. Rubin IC. Cervical pregnancy. Surg Gynecol Obstet. 1911; 13:625-33
  2. Parente JT, Chau-su O, Levy J, Legatt E. Cervical pregnancy analysis. Obstet Gynecol 1983; 62:79-82
  3. Shinagawa S, Nagayama M. Cervical pregnancy as a possible sequela of induced abortion. Am J Obstet Gynecol 1969; 105:282-4
  4. Marcovici I, Rosenzweig BA, Brill Al, Khan M, Scommegna A. Cervical pregnancy. Obstet Gynecol Surv 1994; 49:49-55
  5. Ginsburg ES, Frates MC, Rein MS, et al. Early diagnosis and teratment of cervical pregnancy in an in-vitrofertilization programme. Fertil Steril 1994; 61:966-9
  6. Weyerman PC, Verhoeven ATM, Alberda At. Cervical pregnancy after in vitro fertilization and embryo transfer. Obstet Gynecol 1989; 161:1145-6
  7. Azem F, Yaron Y, Botchan A, et al. Ectopic pregnancy after in vitro fertilization-embryo transfer (IVF/ET); the possible role of the ET technique. J Assist Reprod Genet 1993; 10:302-4
  8. Zouves C, Erenus M, Gomel V. Tubal ectopic pregnancy after in vitro fertilization and embryo transfer; a role for proximal occlusion or salpingectomy after failed distal tubal surgery. Fertil Steril 1991; 56:691-5
  9. Russel JB. The etiology of ectopic pregnancy. Clin Obstet Gynecol 1987;30:181-90 10. Schoolcraft BW. Embryo transfer. Textbook of Assisted Reproductive Techniques 2001:622-26. ll.Vas.W, Suresh PL, Tang-Barton P, et al. Ultra-sonographic differentiation of cervical abortion from cervical pregnancy. J Clin Ultrasound 1984; 12:553-7. 12.Jurkovic D, Hacket E, Campbell S. Diagnosis and treatment of early cervical pregnancy. Ultrasound Obstet Gynecol 1996; 8:373-80. 13.Benson CB, Doubilet PM. Strategies for conservative treatment of cervical ectopic pregnancy. Ultrasound Obstet Gynecol 1996; 8:371-2. 14.Mantelenakis S,Tsalikis T,Grimbizis G,et al. Successful pregnancy after treatmeof cervical pregnancy with methotrexate and curettage. i.Reprod Med 1995; 40:409-14. 15.Badawy SZ, Etman A, Singh M, Murphy K, Mayelli T, Philadelphia M. Uterine artery embolization: the role in obstetrics and gynecology. Clin Imaging 2002; 25:288-95. 16.Dilbaz S, Atasay B, Bilgic S, Caliskan E, Oral S, Haberal A. A case of conservative management of cervical preg¬nancy using selective angiographic embolization. Acta Obstet Gynecol Scand 2001; 80:87-9. 17.Timor-Tritsch IE, Monteagurdo A, Mandeville EO, et al. Successful management of viable cervical pregnancy by local injection of methotrexate guided by trans vaginal ultrasonography Am J Obstet Gynecol 1994; 17:737-9 1