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Journals / GORM:Gynecology Obstetrics & Reproductive Medicine / 2008 / Cilt: 14 - Sayı: 3

16 olguda vulvar intraepitelyal neoplazi tedavisi sonuçları

Treatment results of vulvar intraepithelial neoplasia in 16 women

Cüneyt Eftal TANER
İrem ŞENYUVA
Şevki Göksun GÖKULU
Pages
186–188
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

CONCLUSION: VIN lesions should be surgically treated and careful long term surveillence is mandatory.

📌 3 Key Takeaways

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Objective & Hypothesis:OBJECTIVE: Clinical outcome after surgical treatment of vulvar intraepithelial neoplasia (VIN).
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Key Findings & Data:STUDY DESIGN; 16 women with vulvar intraepithelial neoplasia were reviewed.
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Conclusion & Impact:CONCLUSION: VIN lesions should be surgically treated and careful long term surveillence is mandatory.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

OBJECTIVE: Clinical outcome after surgical treatment of vulvar intraepithelial neoplasia (VIN). STUDY DESIGN; 16 women with vulvar intraepithelial neoplasia were reviewed. Histologic diagnosis was based on classification of the International Society for the Study of Vulvovaginal Diseases (ISSVD). RESULTS: All cases had unifocal lesions in vulvar examination. In 13 cases (81,5%) lesions were white, in 2 cases (12,5%) lesions were papillary in apprereance and in a case ( 6%) there was an ulcerative lesion. In all cases diameter of the vulvar lesions were less than 2 cm. Local excision was performed for VIN 1 lesions. VIN2 and VIN3 lesions underwent simple vulvectomy. Imiquimod therapy was prefferred for a case with VIN3 lesion who refused surgery. In a case with VIN3 lesion squamous cell carcinoma in situ diagnosed after vulvectomy operation. Recurrence of disease has not yet been diagnosed during the follow up period. CONCLUSION: VIN lesions should be surgically treated and careful long term surveillence is mandatory.

Özet

Vulvar intraepitelyal neoplazilerin cerrahi tedavi sonrası klinik sonuçları. Vulvar intraepitelyal neoplazi saptanan 16 olgu araştırıldı. Histolojik tanıda Uluslararası Vulvavajinal Çalışma Grubu Topluluğu sınıflaması kullanıldı. Tüm olguların vulvar muayenesinde unifokal lezyon saptandı. Lezyonlar 13 olguda (%81,5) beyaz, 2 olguda (%12,5) papiller, bir olguda (%6) ülseratif olarak gözlendi. Tüm vulvar lezyon-ların çapı 2 cm'den küçük idi. VİN 1 saptanan lezyonlara lokal eksizyon, VIN2 ve VIN3 saptanan lezyonlarda basit vulvektomi uygulandı. VIN3 saptanan ve cerrahi tedaviyi reddeden bir olguda Imiquimod tedavisi uygulandı. VİN 3 saptanan ve cerrahi tedavi uygulanan bir diğer olguda vulvektomi sonrasında insitu karsinom saptandı. Tüm olguların takip periyodunda rekkürens gözlenmedi.Vulvar intraepitelyal neoplaziler cerrahi tedavi edilebilir. Uzun dönem takiplerinin dikkatle yapılması gereklidir.

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Cite This Article

TANER, C. E., ŞENYUVA, İ., GÖKULU, Ş. G. (2008). 16 olguda vulvar intraepitelyal neoplazi tedavisi sonuçları. GORM:Gynecology Obstetrics & Reproductive Medicine, Cilt: 14 - Sayı: 3, 186–188. https://ajindex.com/articles/227092

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References (1)

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