AI Summary & Key Takeaways
AI InsightCONCLUSIONS: The overall adhesions score did not differed significantly between groups 2,3.Silicone and polyvinyl chloride causes adhesion development in rat model.
📌 3 Key Takeaways
Abstract
OBJECTIVE: Aim of the present study was to determine effect of silicone and polyvinyl chloride in a rat model. STUDY DESIGN: A randomised blind study was performed using a rat model of laparotomy. Setting: Surgical Research laboratory in a university medical school. İntervention(s): Fifty four rats were divided into three groups:Group 1 (n:18),simple laparotomy; and group 2 (n:18) polyvinyl chloride were placed intraperitoneally;Group 3 (n:18),silicone was placed intraperitoneally. Main outcome measure(s): Three weeks after laparotomy,repeat laparotomy was performed and the adhesions were scored. RESULT General adhesion scores in groups 2 and 3 were higher than in group 1 (p<0.05). İn group 1, none of the rats presented adhesion.The results for groups 2 and 3 were similar. CONCLUSIONS: The overall adhesions score did not differed significantly between groups 2,3.Silicone and polyvinyl chloride causes adhesion development in rat model.
Özet
Bu çalışmada amaç rat modeli üzerinde silikon ve polyvinil chlorid'in etkisini belirlemektir. Laparatomi rat modeli kullanılarak, rastgele kör bir çalışma Tıp Fakültesi Üniversitesi, Cerrahi Araştırma Laboratuvarf nda yapıldı. 54 rat 3 gruba ayrıldı. Grup 1(n=18), basit laparatomi uygulanan. Grup 2(n=18), intraperitoneal olarak polyvinyl chloride yerleştirilen. Grup 3 (n:18), intraperitoneal silikon yerleştirilen. Laparatomiden 3 hafta sonra tekrar laparatomi yapıldı ve adezyonlar skorlandı.Grup 2 ve grup3'ün genel adezyon skorları grup 1'den daha fazlaydı (p<0.05). Grup 1'de adezyon yoktu. Grup 2 ve 3'tekiler benzerdi.Grup 2 ve 3 arasında adezyon skorları arasında önemli bir fark bulunamadı. Rat modelinde silikon ve polyvinil chloride adezyon gelişimine neden olmaktadır.