AI Summary & Key Takeaways
AI InsightThis report describes a perimenopausal woman with atypical polypoid adenomyoma of low malignant potential with focal adenocarcinoma on endometrial biopsy who subsequently underwent hysterectomy in which no residual malignant lesion was found.
📌 3 Key Takeaways
Abstract
Atypical polypoid adenomyoma is a rare and benign polypoid lesion of uterus with proliferation of irregular endometrial glands embedded in a smooth muscle stroma. If the lesion contains glands that are sufficiently complex to satisfy the criteria for adenocarcinoma, it is called as atypical polypoid adenomyoma of low malignant potential. Patients most commonly present with abnormal uterine bleeding and more than 90% of patients are premenopausal. Although the lesion is benign, it may occasionally be found to coexist with or to precede endometrial adenocarcinoma. This necessitates a careful management which involves hysterectomy in perimenopausal or postmenopausal patients and hysteroscopy with multiple biopsies in younger women desiring future fertility. This report describes a perimenopausal woman with atypical polypoid adenomyoma of low malignant potential with focal adenocarcinoma on endometrial biopsy who subsequently underwent hysterectomy in which no residual malignant lesion was found.
Özet
Atipik polipoid adenomyom uterusun nadir görülen, benign polipoid bir lezyonudur ve düz kas stroması içinde prolifere olan irregüler endometrial glandlardan oluşur. Lezyon adenokarsinom kriterlerini taşımaya yetecek derecede kompleks glandlar içerirse düşük malignite potansiyelli atipik polipoid adenomyom şeklinde adlandırılır. Hastalarda en sık başvuru semptomu anormal uterin kanamadır ve %90’dan fazlası premenopozaldır. Lezyon benign olmasına rağmen bazen beraberinde endometrial adenokarsinom bulunabilir veya lezyon adenokarsinoma ilerleyebilir. Bu nedenle dikkatli bir yak- laşım gerekir. Perimenopozal veya postmenopozal hastalarda histerektomi tercih edilirken fertilite arzusu olan genç hastalarda histeroskopi ve histeroskopik biopsiler tercih edilmelidir. Burada endometrial biopside düşük malignite potansiyelli atipik polipoid adenomyomda fokal endometrial adenokarsinom saptanan perimenopozal bir hasta sunulmaktadır. Hastaya histerektomi yapılmış ve rezidü malign lezyon saptanmamıştır.