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Journals / Gülhane Tıp Dergisi / 2009 / Cilt: 51 - Sayı: 2

Yetişkin blastemal Wilms tümörüne benzerlik gösteren renal primer primitif nöroektodermal tümörün immünohistokimyasal özellikleri: Olgu sunumu

The immunohistochemical features of the renal primary primitive neuroectodermal tumor mimicking adult blastemal Wilms tumor: A case report

Ayhan ÖZCAN
Ali Fuat ÇİÇEK
Şeref BAŞAL
Bülent KURT
Ömer GÜNHAN
Uğur BOZLAR
Pages
112–115
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this report, a rare renal primary primitive neuroectodermal tumor showing both CD99 and Wilms tumor 1 expression is presented.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Primary primitive neuroectodermal tumor of the kidney is a rare and aggressive tumor.
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Key Findings & Data:A 44-year-old man was admitted to the hospital with left flank pain and hematuria.
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Conclusion & Impact:In this report, a rare renal primary primitive neuroectodermal tumor showing both CD99 and Wilms tumor 1 expression is presented.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Primary primitive neuroectodermal tumor of the kidney is a rare and aggressive tumor. Its distinction from other primary renal tumors is clinically important due to different therapeutic management. A 44-year-old man was admitted to the hospital with left flank pain and hematuria. In computerized tomography, a mass in left kidney was detected and nephrectomy was performed. Microscopically the tumor was composed of small round cells. Immunohistochemically, diffuse strong positivity for CD 99 (MIC2) and NSE, and focal positivity for Wilms tumor 1 were determined in the tumor cells. In this report, a rare renal primary primitive neuroectodermal tumor showing both CD99 and Wilms tumor 1 expression is presented.

Özet

Böbreğin primer primitif nöroektodermal tümörü seyrek görülen agresif bir tümördür. Farklı tedavi yaklaşımları nedeniyle, klinik olarak bu tümörün diğer primer renal tümörlerden ayırımı önemlidir. Kırk dört yaşında erkek hasta sol yan ağrısı ve hematüri şikayetleri ile hastaneye başvurdu. Bilgisayarlı tomografide sol böbrekte kitle saptandı ve nefrektomi uygulandı. Mikroskopik olarak, tümör küçük yuvarlak hücrelerden oluşmaktaydı. İmmünohistokimyasal olarak, tümör hücrelerinde yaygın ve kuvvetli CD 99 (MIC2) ve NSE, fokal Wilms tümör 1 pozitifliği saptandı. Bu yazıda CD 99 ve Wilms tümör 1 ekspresyonu gösteren ve seyrek görülen renal primer primitif nöroektodermal tümör olgusu sunulmuştur.

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Cite This Article

ÖZCAN, A., ÇİÇEK, A. F., BAŞAL, Ş., KURT, B., GÜNHAN, Ö., BOZLAR, U. (2009). Yetişkin blastemal Wilms tümörüne benzerlik gösteren renal primer primitif nöroektodermal tümörün immünohistokimyasal özellikleri: Olgu sunumu. Gülhane Tıp Dergisi, Cilt: 51 - Sayı: 2, 112–115. https://ajindex.com/articles/226350

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