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Journals / Gülhane Tıp Dergisi / 2004 / Cilt: 46 - Sayı: 4

Fetal lung type pulmonary adenocarcinoma (Case report)

Fetal akciğer tipi pulmoner adenokarsinoma (Olgu sunumu)

MEHMET GAMSIZKAN
Bülent KURT
M. Salih DEVECİ
Ömer GÜNHAN
Pages
347–350
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The management and prognosis of this tumor are different from that of pulmonary blastoma and pleuropulmonary blastoma and may also cause difficulties in differential diagnosis.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Pulmonary adenocarcinoma that histologically resembles fetal lung is a rare malignant epithelial tumor.
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Key Findings & Data:A solitary pulmonary nodule was determined in right lung upper lobe of a 62-year-old man, and fine needle aspiration, intraoperative frozen examination, and pneumonectomy were applied respectively.
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Conclusion & Impact:The management and prognosis of this tumor are different from that of pulmonary blastoma and pleuropulmonary blastoma and may also cause difficulties in differential diagnosis.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Adenokarsinom · Akciğer · Pnömonektomi

Abstract

Pulmonary adenocarcinoma that histologically resembles fetal lung is a rare malignant epithelial tumor. A solitary pulmonary nodule was determined in right lung upper lobe of a 62-year-old man, and fine needle aspiration, intraoperative frozen examination, and pneumonectomy were applied respectively. After the histopathologic and immunohistochemical investigations, the case was diagnosed as fetal lung type pulmonary adenocarcinoma. The management and prognosis of this tumor are different from that of pulmonary blastoma and pleuropulmonary blastoma and may also cause difficulties in differential diagnosis.

Özet

Fetal akciğere histolojik olarak benzerlik gösteren pulmoner adenokarsinoma, akciğerin seyrek görülen malign epitelyal bir tümörüdür. Sağ akciğer üst lobunda soliter nodül saptanan 62 yaşında erkek hastaya ince iğne aspirasyonu, intraoperatif frozen inceleme ve sonrasında pnömonektomi uygulanmıştır. Histopatolojik ve immünohistokimyasal yöntemler ile olguya fetal akciğer tipi pulmoner adenokarsinoma tanısı konulmuştur. Pulmoner blastoma ve plöropulmoner blastoma ile ayırıcı tanıda güçlüğe yol açabilen bu tümörün, tedavisi ve prognozu farklılık gösterir.

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Cite This Article

GAMSIZKAN, M., KURT, B., DEVECİ, M. S., GÜNHAN, Ö. (2004). Fetal lung type pulmonary adenocarcinoma (Case report). Gülhane Tıp Dergisi, Cilt: 46 - Sayı: 4, 347–350. https://ajindex.com/articles/226250

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References (9)

  1. Colby, T.V., Koss, M.N., Travis., W.D.: Welldifferantiated fetal adenocarcinoma (pulmonary endodermal tumor), Eds.: Rosai J, Tumors of the lower respiratory tract, 3rd edition, Washington, AFIP,1995,p.395-403
  2. Kradin, R.L., Young, R.H., Dickersin, G.R., Kirkham, S.E., Mark, E.J.: Pulmoner blastoma with argyrophil cells lacking sarcomatous features (pulmonary endodermal tumor resembling fetal lung). Am J Surg Pathol 1982;6:165-172
  3. DiFurio, M.J., Auerbach, A., Kaplan, K.J., Welldifferentiated fetal adenocarcinoma: rare tumor in the pediatric population, Pediatr Dev Pathol 2003 6(6):564-7. 350 4. Koss, M.N., Hochholzer, L., O'Leary, T.: Pulmonary blastomas. Cancer 1991; 67: 2368- 2381
  4. Travis, W.D., Colby, T.V., Corrin, B., Shimosato, Y., Brambilla, E., editors.: Histological typing of lung and pleural tumours with contributions by pathologists from 14 countries. World health organization international histological classification of tumors, XIII, 3rd ed. Berlin/Heidelberg (Germany): Springer-Verlag; 1999
  5. Nakatani, Y., Kitamura, H., İnayama, Y., et al.: Pulmonary adenocarcinoma of the fetal lung type: a chilinicopathologic study indicating differences in histology, epidemiology, and natural history of low-grade and high-grade forms. Am J Surg Pathol 1998;22:399-411
  6. Nakatani, Y., Masudo, K., Miyagi, Y., et al.: Aberrant Nuclear localization and gene mutation of B-catenin in low-grade adenocarcinoma of fetal lung type: up-regulation of the wnt signaling pathway maybe a common denomiator for the development of tumors that from morules. Mod Pathol 2002; 15(6):617-624
  7. Yamazaki, K.: Pulmonary well-differentiated fetal adenocarcinoma expressing lineage-specific factors (TTF-1 and GATA-6) to respiratory epithelial differantiation: an immunohistochemical and ultrastructal study. Virchows Arch 2003 442:393-399
  8. Hsu, L.H., Mao, T.L., Shih, C.S., et al.: Case report, Well-differantiated fetal adenocarcinoma of the lung. J Formos Med Assoc 2000, 99; 425- 427
  9. S-C., Chao, J.Y-Y., Lee.: Well-differentiated fetal adenocarcinoma presenting with cutaneous metastases. Br J Dermatol 2004; 150(4): 778 - 780.