Journals / Gülhane Tıp Dergisi / 2009 / Cilt: 51 - Sayı: 2

Polysomnographic findings in manic patients

Manik hastalarda polisomnografi bulguları

Pages
97–100
DOI
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⚡ TL;DR(Too Long; Didn't Read)

These results demonstrated that total sleep time shortened in manic patients consistent with clinical features of the disorder, but there was no change in sleep structure.

📌 3 Key Takeaways

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Objective & Hypothesis:Although sleep disturbance, particularly decreased need for sleep, is a characteristic feature of mania, there are very few systematic polysomnographic studies investigating the sleep pattern in mania.
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Key Findings & Data:Seven male patients with a DSM-III-R diagnosis for a current manic episode of bipolar disorder without any drug use for at least 2 weeks were studied with respect to polysomnography for two consecutive nights.
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Conclusion & Impact:These results demonstrated that total sleep time shortened in manic patients consistent with clinical features of the disorder, but there was no change in sleep structure.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Although sleep disturbance, particularly decreased need for sleep, is a characteristic feature of mania, there are very few systematic polysomnographic studies investigating the sleep pattern in mania. In this study it was aimed to investigate the sleep pattern in manic patients with no treatment started. Seven male patients with a DSM-III-R diagnosis for a current manic episode of bipolar disorder without any drug use for at least 2 weeks were studied with respect to polysomnography for two consecutive nights. Their sleep variables were compared with 7 age- and sex- matched healthy controls. Manic patients showed decreased time in bed, decreased total sleep time and decreased sleep period time when compared to healthy controls. Despite impaired sleep continuity, there were no significant differences between the two groups regarding sleep structure (Frequency and percentage of sleep period). Compared to healthy controls, no differences were detected in manic patients with respect to the variables of slow wave sleep and rapid eye movement (REM). These results demonstrated that total sleep time shortened in manic patients consistent with clinical features of the disorder, but there was no change in sleep structure.

Özet

Manide uyku bozukluğu, özellikle azalmış uyku ihtiyacı belirgin klinik özelliklerden birisi olmasına rağmen, uyku yapısını inceleyen az sayıda sistematik polisomnografi çalışması mevcuttur. Bu çalışmada tedaviye başlanmamış manik hastalarda uyku yapısını incelemek amaçlanmıştır. DSM-III-R'ye göre bipolar bozuklukları halen manik dönemde olan, en az iki hafta ilaç kullanmamış yedi erkek hastaya iki gece polisomnografik çalışma yapılmıştır. Hastaların uyku değişkenleri, aynı yaş ve cinsiyet grubundan yedi sağlıklı denek ile karşılaştırılmıştır. Manik hastalarda normal kontrol grubuna göre yatakta geçen süre, toplam uyku süresi ve uyku periyod zamanındaki azalma anlamlı bulunmuştur. Uyku devamlılığında bu bozulmaya rağmen, uyku yapısında (uyku dönemlerinin sıklık ve yüzdesinde) anlamlı farklılık saptanmamıştır. Ayrıca manik hastaların yavaş dalga uykusu ve “Rapid eye movement” (REM) değişkenleri normallere göre farklı bulunmamıştır. Bu sonuçlar manik hastalarda, hastalığın kliniği ile uyumlu olarak uyku süresinin azaldığını, fakat uykunun yapısında değişiklik olmadığını göstermiştir.

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Cite This Article

ÖZGEN, F., AYKIN, U., YETKİN, S., AYDIN, H. (2009). Polysomnographic findings in manic patients. Gülhane Tıp Dergisi, Cilt: 51 - Sayı: 2, 97–100. https://ajindex.com/articles/226142

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