Journals / Gülhane Tıp Dergisi / 2012 / Cilt: 54 - Sayı: 2

Evaluation of retinal nerve fiber thickness in myopic eyes by optical coherence tomography

Miyopik gözlerde retina sinir lifi kalınlığının optik koherens tomografi ile değerlendirilmesi

Pages
151–154
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Retinal nerve fiber layer should be interpreted cautiously considering axial length and refractive error.

📌 3 Key Takeaways

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Objective & Hypothesis:The purpose of this study was to evaluate the relationship between retinal nerve fiber layer thickness measured by optical coherence tomography and the axial length/refractive error in myopic eyes.
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Key Findings & Data:Medical records of 30 healthy male subjects and 50 male patients with miyopia (spherical equivalent between -1.0 D and -8.75 D) were analyzed retrospectively in the study.
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Conclusion & Impact:Retinal nerve fiber layer should be interpreted cautiously considering axial length and refractive error.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

The purpose of this study was to evaluate the relationship between retinal nerve fiber layer thickness measured by optical coherence tomography and the axial length/refractive error in myopic eyes. Medical records of 30 healthy male subjects and 50 male patients with miyopia (spherical equivalent between -1.0 D and -8.75 D) were analyzed retrospectively in the study. Spherical equivalent, axial length, mean and four quadrant retinal nerve fiber layer thickness measurements of one eye were recorded in all patients. Retinal nerve fiber layer thickness measurements were compared between the two groups. Relationship between axial length/spherical equivalent and retinal nerve fiber layer thickness was analyzed. The mean axial length in the control and myopic groups was 23.36±0.65 mm and 25.58±1.50 mm, respectively (t=7.59, p<0.0001). The mean retinal nerve fiber layer thickness in the control and myopic groups was 108.13±9.50 &#956;m and 100.88±9.05 &#956;m, respectively (t=3.40, p=0.001). A negative correlation was detected between axial length/spherical equivalent and retinal nerve fiber layer thickness in myopic patients, respectively (r=-0.377, p=0.001, r=-0.452, p<0.001). Retinal nerve fiber layer thickness is affected from the axial length and refractive error. Retinal nerve fiber layer should be interpreted cautiously considering axial length and refractive error.

Özet

Bu çalışmanın amacı, miyopik gözlerde optik koherens tomografi ile ölçülen retina sinir lifi tabakası kalınlığı ile aksiyel uzunluk ve kırma kusuru arasındaki ilişkiyi değerlendirmektir. Çalışmada 20 ile 30 yaş arasında, 30 sağlıklı erkek bireyin ve 50 miyop (sferik eşdeğeri -1.00 ile -8.75 D arasında) erkek hastanın kayıtları retrospektif olarak incelendi. Tüm hastaların bir gözünün sferik eşdeğer, aksiyel uzunluk, ortalama ve dört kadran retina sinir lifi tabakası kalınlık ölçümleri kaydedildi. Retina sinir lifi tabakası kalınlıkları iki grup arasında karşılaştırıldı. Aksiyel uzunluk ve sferik eşdeğer ile retina sinir lifi tabakası kalınlığı arasındaki ilişki değerlendirildi. Ortalama aksiyel uzunluk, kontrol grubunda 23.36±0.65 mm, miyop hastalarda 25.58±1.50 mm olarak bulundu (t=7.59, p<0.0001). Ortalama retina sinir lifi tabakası kalınlığı, kontrol grubunda 108.13±9.50 μm, miyop hastalarda 100.88±9.05 μm olarak bulundu (t=3.40, p=0.001). Miyop hastalarda aksiyel uzunluk ve sferik eşdeğer ile retina sinir lifi tabakası kalınlığı arasında negatif korelasyon saptandı (r=-0.377, p=0.001, r=-0.452, p<0.001). Retina sinir lifi tabakası kalınlığı aksiyel uzunluk ve kırma kusurundan etkilenmektedir. Retina sinir lifi tabakası, aksiyel uzunluk ve kırma kusuru dikkate alınarak yorumlanmalıdır.

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Cite This Article

KAR, T., AYATA, A., AKSOY, Y., ÜNAL, M. H., ERŞANLI, D. (2012). Evaluation of retinal nerve fiber thickness in myopic eyes by optical coherence tomography. Gülhane Tıp Dergisi, Cilt: 54 - Sayı: 2, 151–154. https://ajindex.com/articles/226110

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