Journals / Gülhane Tıp Dergisi / 1998 / Cilt: 40 - Sayı: 4

Helicobacter pylori infection in patients with cholelithiasis

Kolelitiyazisli hastalarda Helicobacter pylori enfeksiyonu

Pages
475–479
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In conclusion; Hp infection frequency was not different between the two groups (p>0.05).

📌 3 Key Takeaways

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Objective & Hypothesis:Helicobacter pylori (Hp) is the most common cause of chronic infection all over the world.
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Key Findings & Data:Gallstone is an important disease with its 10-15 % prevalence in adults.
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Conclusion & Impact:In conclusion; Hp infection frequency was not different between the two groups (p>0.05).
🔬Design:Research Article
📍Scope:1 specimen
⚙️Variables:Domain Parameters

Abstract

Helicobacter pylori (Hp) is the most common cause of chronic infection all over the world. Gallstone is an important disease with its 10-15 % prevalence in adults. This study was performed to investigate the relationship between cholelithiasis and Hp infection. Thirty cholelithiasis cases diagnosed by ultrasound were included into the study ( 26 females, 4 males and their mean age was 36.5 ± 8.64 years). The control group was consisted of, Thirty subjects who have dispeptic complaints but without gallstone (15 females, 11 males and their mean age 33.6±14.72 years). All had gastroscopic examination. During gastroscopy, biopsies were performed (1 specimen for rapid urease test and 4 specimens for histopatological diagnosis 2 from antrum and 2 from corpus). Sydney classification was used in histopatological examination. In the patient group 24 had, Hp (+) chronic superficial gastritis, 3 had Hp (-) chronic superficial gastritis. 1 Hp (+) and 1 Hp (-) chronic atrophie gastritis and 1 Hp (-) normal gastric mucosa were also diagnosed. 9 had activity in the patient group, the results were as follows: 20 Hp (+) chronic superficial gastritis, 4 Hp (+) chronic atrophie gastritis, 1 Hp (-) chronic atrophie gastritis, 1 Hp (-) normal gastric mucosa and 1 Hp (-) edemateus gastric mucosa. 13 had activity in the control group. In statistical analysis, chisqare and student- t tests were used. In conclusion; Hp infection frequency was not different between the two groups (p>0.05). However lilammatory activity was significantly higher in control group than the patient group (p<0.05).

Özet

Helicobacter Pylori (Hp) dünyadaki en yaygın kronik enfeksiyon nedenidir. Safra kesesi taşı ise erişkin nüfusun %10-15' inde görülen önemli bir hastalıktır. Bu çalışmanın amacı, kolelitiyazis ve Hp enfeksiyonu arasındaki ilişkiyi araştırmaktı. Çalışmaya hasta grubu olarak, ultrasonografi ile kolelitiyazis tanısı konan 30 olgu (26'sı kadın, 4' ü erkek ve yaş ortalamaları 36.5± 8.64 ) alındı.Kontrol grubu olarak, dispeptik şikayeti olan, safra kesesi taşı bulunmayan 30 vaka (19' u kadın, 11' i erkek ve yaş ortalamaları 33.6 ± 14.72) idi. Bu hastaların hepsine gastroskopi uygulandı. Gastroskopi sırasında ; hızlı üreaz testi için 1 adet, histopatolojik tanı için 4 adet (2'si antrumdan, 2'si korpustan) biyopsi alındı. Histopatolojik inceleme Sydney klasifikasyonuna göre yapıldı, incelemelerde aktivite kriteri olarak polimorfonükleef nötrofillerin infiltrasyonu esas alındı. Hasta grubunda ; 24 Hp (+) ve 3 Hp (-) kronik yüzeyel gastrit, 1 Hp (+) ve 1 Hp (-) kronik atrofik gastrit, 1 Hp (-) ve T normal mide mukozası tespit edildi. Bunlardan 9'unda aktivite tespit edildi. Kontrol grubunda ise, 20 Hp (+) ve 3 Hp (-) kronik yüzeyel gastrit, 4 Hp (+) ve 1 Hp (-) kronik atrofik gastrit, 1 Hp (-) normal mide mukozası, 1 Hp (-) ödemli mide mukozası tespit edildi. Bunlardan 13'ünde aktivite tespit edildi, istatistiki değerlendirme için ki-kare ve student-t testi kullanıldı. Sonuç olarak ; her iki grup arasında Hp enfeksiyon sıklığı farklı değildi (P>0.05). Ancak enflamatuvar aktivite kontrol grubunda,' hasta grubuna göre anlamlı olarak yüksek idi (p<0.05).

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Cite This Article

UYGUN, A., ARSLAN, H., ÇETİN, C., BULUCU, F., ERDİL, A., SARAÇOĞLU, E., TÜZÜN, A., KARAEREN, N., DAĞALP, K. (1998). Helicobacter pylori infection in patients with cholelithiasis. Gülhane Tıp Dergisi, Cilt: 40 - Sayı: 4, 475–479. https://ajindex.com/articles/226064