Journals / Gülhane Tıp Dergisi / 2005 / Cilt: 47 - Sayı: 4

Relationship between left ventricular geometry and heart rate variability in patients with mitral valve prolapsus

Mitral kapak prolapsuslu hastalarda kalp hızı değişkenliği ve sol ventrikül geometrisi arasındaki ilişki

Pages
260–264
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

These patients must be followed carefully with regard to arrhythmia.

📌 3 Key Takeaways

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Objective & Hypothesis:Relationship between left ventricular geometry and heart rate variability in patients with mitral valve prolapsus Mitral valve prolapsus has an increased risk of arrhythmia.
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Key Findings & Data:In this study, we aimed to examine if heart rate variability is different in patients with mitral prolapsus, and if it is, the relationship between the heart rate variability and eccentric hypertrophy.
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Conclusion & Impact:These patients must be followed carefully with regard to arrhythmia.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Kalp ventrikülleri · Kalp hızı · Mitral kapak prolapsı

Abstract

Relationship between left ventricular geometry and heart rate variability in patients with mitral valve prolapsus Mitral valve prolapsus has an increased risk of arrhythmia. In this study, we aimed to examine if heart rate variability is different in patients with mitral prolapsus, and if it is, the relationship between the heart rate variability and eccentric hypertrophy. Forty eight subjects were divided into four groups according to the presence or absence of eccentric hypertrophy and mitral valve prolapsus: mitral valve prolapsus and left ventricular eccentric hypertrophy positive (Group 1, n=12, 25±4 years old, male to female ratio: 4/8), mitral valve prolapsus positive and left ventricular eccentric hypertrophy negative (Group 2, n=12, 23±5 years old, male to female ratio: 5/7), mitral valve prolapsus negative and left ventricular eccentric hypertrophy positive (Group 3, n=12, 26±7 years old, male to female ratio: 7/5), and mitral valve prolapsus and left ventricular eccentric hypertrophy negative (Group 4, n=12, 24±4 years old, male to female ratio: 7/5). The patients were asked to carry Holter electrocardiography device for 24 hours in order to measure the heart rate variability. Ventricular extrasystoles and automatically estimated heart rate variability parameters of time domain were compared among the groups. Age and sex were not different among the groups. Indexes, SDANN and rMSDD, were significantly lower in the patients with left ventricular eccentric hypertrophy (Groups 1 and 3) than in the patients without eccentric hypertrophy (Groups 2 and 4) (p<0.01). In contrast, the patients with mitral prolapsus (Groups 1 and 2) showed heart rate variability indexes that were not different significantly in relation to the patients without mitral valve prolapsus (Groups 3 and 4) (p>0.01). Ventricular extrasystoles were also higher in Group 1 patients (p<0.001). If there is no eccentric hypertrophy in patients with prolapsus, heart rate variability is normal. The eccentric hypertrophy is associated with decreased heart rate variability. These patients must be followed carefully with regard to arrhythmia.

Özet

Mitral kapak prolapsusu, aritmi riski ile beraber olan bir durumdur. Bu çalışmada mitral prolapsuslu hastalarda kalp hızı değişkenliğinde farklılık olup olmadığı, değişiklik varsa bunun sol ventrikül geometrisi ile ilişkisi araştırıldı. Çalışma grubunu oluşturan 48 birey mitral kapak prolapsusu ve sol ventrikül egzantrik hipertrofisi varlığına göre dört gruba ayrıldı: mitral kapak prolapsusu ve sol ventrikül egzantrik hipertrofisi olan (Grup 1, n=12, 25±4 yıl yaş, erkek/dişi oranı: 4/8); mitral kapak prolapsusu olan ancak sol ventrikül egzantrik hipertrofisi olmayan (Grup 2, n=12, 23±5 yıl yaş, erkek/dişi oranı: 5/7); mitral kapak prolapsusu olmayan ancak sol ventrikül egzantrik hipertrofisi olan (Grup 3, n=12, 26±7 yıl yaş, erkek/dişi oranı: 7/5); mitral kapak prolapsusu ve sol ventrikül egzantrik hipertrofisi olmayan (Grup 4, n=12, 24±4 yıl yaş, erkek/dişi oranı: 7/5). Kalp hızı değişkenliği için, 24 saat ambulatuvar EKG alındı. Ventriküler ekstrasistoller ve otomatik hesaplanan zamana dayalı kalp hızı değişkenliği karşılaştırıldı. Gruplarda yaş ve cinsiyet farklılığı yoktu. "Tüm normal RR intervallerinin standart sapması" ve "komşu RR intervalleri arasındaki farkın karelerinin ortalamasının karekökü", sol ventrikül egzantrik hipertrofili Grup 1 ve 3 hastalarda, egzantrik hipertrofi olmayan Grup 2 ve 4 hastalar ile karşılaştırıldığında anlamlı olarak daha düşüktü (p 0.01). Prolapsuslularda (Grup 1 ve 2), olmayanlara göre (Grup 3 ve 4) değişkenlik açısından fark yoktu (p>0.01). Ventriküler ekstrasistoller, Grup 1 hastalarda daha fazlaydı (p<0.001). Mitral prolapsusunda egzantik hipertrofi yoksa kalp hızı değişkenliği normal iken, egzantrik hipertofisi var ise azalmaktadır. Bu hastaların aritmi yönünden risk altında oldukları akılda tutulmalıdır.

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Cite This Article

UZUN, M., SAĞ, C., ÖZKAN, M., BAYSAN, O., ERİNÇ, K., YOKUŞOĞLU, M., SAĞLAM, K., GENÇ, C., IŞIK, E. (2005). Relationship between left ventricular geometry and heart rate variability in patients with mitral valve prolapsus. Gülhane Tıp Dergisi, Cilt: 47 - Sayı: 4, 260–264. https://ajindex.com/articles/225667

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