Journals / Gülhane Tıp Dergisi / 2011 / Cilt: 53 - Sayı: 2

Findings of confocal microscopy, ultrasonic biomicroscopy and optical coherence tomography in lipid keratopathy

Lipid keratopatide konfokal mikroskopi, ultrasonik biyomikroskopi ve optik koherens tomografi bulguları

Pages
126–129
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

As also observed in this case presented, confocal microscopy, ultrasonic biomicroscopy and optical coherence tomography are beneficial for in vivo investigation of the corneal lipid degeneration.

📌 3 Key Takeaways

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Objective & Hypothesis:In this study we aimed to present the findings of confocal microscopy, ultrasonic biomicroscopy and optical coherence tomography in lipid keratopathy which is a rare corneal disease.
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Key Findings & Data:A 54-year-old male patient with no history of eye disease or systemic disorder was admitted to our clinic with symptom of decreased vision in his right eye.
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Conclusion & Impact:As also observed in this case presented, confocal microscopy, ultrasonic biomicroscopy and optical coherence tomography are beneficial for in vivo investigation of the corneal lipid degeneration.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

In this study we aimed to present the findings of confocal microscopy, ultrasonic biomicroscopy and optical coherence tomography in lipid keratopathy which is a rare corneal disease. A 54-year-old male patient with no history of eye disease or systemic disorder was admitted to our clinic with symptom of decreased vision in his right eye. His visual acuity was 0.7 in the right eye and 1.0 in the left. Biomicroscopy revealed mild corneal edema, increased corneal thickness, ring shaped intrastromal fat accumulation, and penetration of feeding vessels in his right eye. Confocal microscopy supported these findings and additionally revealed perivascular inflammatory cell infiltration and destruction of corneal lamellas and keratocytes. Ultrasonic biomicroscopic examination revealed corneal posterior bulging in Descemet membrane with destruction by infiltration of the hyperecogenic substance. Regions of stromal lipid accumulation, vascular infiltration and posterior bulging were also seen in sections of corneal optical coherence tomography. As also observed in this case presented, confocal microscopy, ultrasonic biomicroscopy and optical coherence tomography are beneficial for in vivo investigation of the corneal lipid degeneration.

Özet

Bu çalışmada nadir bir kornea hastalığı olan lipid keratopatideki konfokal mikroskopi, ultrasonik biyomikroskopi ve optik koherens tomografi bulgularını sunmayı amaçladık. Göz hastalığı ya da sistemik rahatsızlık öyküsü bulunmayan 54 yaşındaki bir erkek hasta sağ gözündeki görme azlığı şikayetiyle kliniğimize kabul edildi. Olgunun görme düzeyleri sağda 0.7, solda 1.0 idi. Biyomikroskopide olgunun sağ gözünde hafif korneal ödem, artmış korneal kalınlık, halka şeklinde stroma içi yağ birikimi ve besleyici damarların penetrasyonu mevcuttu. Konfokal mikroskopi bu bulguları destekledi ve aynı zamanda perivasküler inflamatuvar hücre infiltrasyonunu, korneal katmanlara ve keratositlere ait yıkımı da ortaya çıkardı. Ultrasonik biyomikroskobik inceleme korneada hiperekojen madde infiltrasyonu ile yıkılan Descemet zarıyla birlikte arkaya doğru bombeleşmeyi ortaya koydu. Stromal lipid birikimi, vasküler infiltrasyon ve arkaya doğru bombeleşme bölgesi korneal optik koherens tomografi kesitlerinde de gözlendi. Bu olgu sunumunda da görüldüğü üzere konfokal mikroskopi, ultrasonik biyomikroskopi ve optik koherens tomografi korneadaki lipid dejenerasyonunun canlı ortamda incelenmesinde faydalı bulunmuştur.

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Cite This Article

TÜRK, A., ERDÖL, H. (2011). Findings of confocal microscopy, ultrasonic biomicroscopy and optical coherence tomography in lipid keratopathy. Gülhane Tıp Dergisi, Cilt: 53 - Sayı: 2, 126–129. https://ajindex.com/articles/225573

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