Journals / Gülhane Tıp Dergisi / 2011 / Cilt: 53 - Sayı: 4

The comparison of maternal body mass index and weight gain with maternal biochemical parameters and fetal birth weight in patients with gestational diabetes mellitus

Gestasyonel diyabetes mellitus olgularında maternal vücut kitle indeksi ve kilo alımı ile maternal biyokimyasal değerler ve fetal doğum ağırlığının karşılaştırılması

Pages
237–242
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

However better and more strict antenatal follow-up and appropriately timing of diabetes treatment may have contributed to the decrease in negative feto-maternal results.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:In this study, we aimed to investigate the effects of pre-pregnancy body mass index (BMI) and maternal weight gain on maternal biochemical parameters and fetal birth weight by comparing the cases with gestational diabetes mellitus and normal controls.
📊
Key Findings & Data:Thirty seven women with gestational diabetes mellitus and 42 women with a negative result of 50 g oral glucose tolerance test constituted the study and control groups, respectively.
💡
Conclusion & Impact:However better and more strict antenatal follow-up and appropriately timing of diabetes treatment may have contributed to the decrease in negative feto-maternal results.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

In this study, we aimed to investigate the effects of pre-pregnancy body mass index (BMI) and maternal weight gain on maternal biochemical parameters and fetal birth weight by comparing the cases with gestational diabetes mellitus and normal controls. Thirty seven women with gestational diabetes mellitus and 42 women with a negative result of 50 g oral glucose tolerance test constituted the study and control groups, respectively. Maternal demographic charecteristics, weight gain during pregnancy, BMIs before gestation and during test, maternal metabolic parameters and birth weight of term newborn were recorded in the study. There was a significant difference between the study and control groups with respect to triglyceride levels (253.7±71.5 versus 188.5±68.3 mg/dl), whereas there were no significant differences with respect to BMI and weight gain during pregnancy. There were no significant differences between the two groups regarding HOMA-IR values and fetal birth weight. On the contrary of the literature knowledge we did not detect any relation between increase in BMI and excessive weight gain, and negative feto-maternal effects in the present study. However better and more strict antenatal follow-up and appropriately timing of diabetes treatment may have contributed to the decrease in negative feto-maternal results.

Özet

Bu çalışmada gebelik öncesi vücut kitle indeksi (BMI) ve gebelikte kilo alımının maternal biyokimyasal değerler ile fetal doğum ağırlığına olan etkilerini gestasyonel diyabetes mellituslu olguları normal gebelikler ile karşılaştırarak araştırmayı amaçladık. Gestasyonel diyabetes mellitus tanısı almış 37 kadın çalışma grubunu ve 50 gr’lık oral glikoz tolerans testi negatif olan 42 kadın kontrol grubunu oluşturdu. Maternal demografik özellikler, gebelik süresince kilo alımı, gebelik öncesi ve test sırasındaki BMI, maternal metabolik parametreler, term yenidoğanın kilosu kaydedilmiştir. Çalışma ve kontrol grubu arasında trigliserid değerleri açısından (253.7±71.5’e 188.5±68.3 mg/ dl) anlamlı farklılık saptanırken (p<0.001), BMI ve gebelik süresindeki kilo alımı açısından anlamlı farklılık saptanmamıştır. HOMA-IR ve fetal doğum ağırlığı açısından her iki grup arasında anlamlı farklılık saptanmamıştır. Çalışmamızda literatürün aksine BMI yüksekliği ve aşırı kilo alımı ile olumsuz feto-maternal sonuçlar arasında bir ilişki saptanmamıştır. Ancak gestasyonel diyabetes mellitus tanısı konulan olgularda, daha iyi ve sıkı antenatal takip ile diyabet tedavisinin zamanında planlanması olumsuz feto-maternal sonuçların azaltılmasına neden olmuş olabilir.

🔖

Cite This Article

ALANBAY, İ., ÇOKSÜER, H., ERCAN, C. M., KESKİN, U., ÖZTÜRK, M., KARAŞAHİN, K. E., TAPAN, S., BAŞER, İ. (2011). The comparison of maternal body mass index and weight gain with maternal biochemical parameters and fetal birth weight in patients with gestational diabetes mellitus. Gülhane Tıp Dergisi, Cilt: 53 - Sayı: 4, 237–242. https://ajindex.com/articles/225373

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (16)

  1. Reece EA, Homko C, Miodovnik M, Langer O. A consensus report of the Diabetes in Pregnancy Study Group of North America Conference, Little Rock, Arkansas, May 2002. J Matern Fetal Neonatal Med 2002; 12: 362-364
  2. Akbay E, Torun Sİ, Yalçınkaya H, Uzunçakmak C, Toklucu G. Prevalence of gestational diabetes among pregnant women attending in MD Sadi Konuk Training and Research Hospital. Turkiye Klinikleri J Gynecol Obst 2010; 20: 170-175
  3. Clinical management guidelines for obstetriciangynecologists. ACOG Practice Bulletin No
  4. American College of Obstetricians and Gynecologists. Obstet Gynecol 2001; 98: 525-538
  5. Türkmen M, Aydoğdu SA, Uygur O, Odabaşı AR, Yüksel H, Tosun FA. Neonatal complications in infants born to diabetic mothers. Turkiye Klinikleri J Pediatr 2008; 17: 8-14
  6. Reece EA. The fetal and maternal consequences of gestational diabetes mellitus. J Matern Fetal Neonatal Med 2010; 23: 199-203
  7. Colditz GA, Willett WC, Rotnitzky A, Manson JE. Weight gain as a risk factor for clinical diabetes mellitus in women. Ann Intern Med 1995; 122: 481-486
  8. Cedergren MI. Optimal gestational weight gain for body mass index categories. Obstet Gynecol 2007; 110: 743-744
  9. Kiel DW, Dodson EA, Artal R, Boehmer TK, Leet TL. Gestational weight gain and pregnancy outcomes in obese women: how much is enough? Obstet Gynecol 2007; 110: 752-758
  10. DeVader SR, Neeley HL, Myles TD, Leet TL. Evaluation of gestational weight gain guidelines for women with normal prepregnancy body mass index. Obstet Gynecol 2007; 110: 745-751
  11. LuGC, RouseDJ, DuBard M, Cliver S, Kimberlin D, Hauth JC. The effect of the increasing prevalence of maternal obesity on perinatal morbidity. Am J Obstet Gynecol 2001; 185: 845-849
  12. Rodrigues S, Robinson EJ, Ghezzo H, Gray-Donald K. Interaction of body weight and ethnicity on risk of gestational diabetes mellitus. Am J Clin Nutr 1999; 70: 1083-1089
  13. Solomon CG, Willett WC, Carey VJ, et al. A prospective study of pregravid determinants of gestational diabetes mellitus. JAMA 1997; 278: 1078-1083
  14. Torloni MR, Betran AP, Horta BL, et al. Prepregnancy BMI and the risk of gestational diabetes: a systematic review of the literature with meta-analysis. Obes Rev 2009; 10: 194-203
  15. Saldana TM, Siega-Riz AM, Adair LS, Suchindran C. The relationship between pregnancy weight gain and glucose tolerance status among black and white women in central North Carolina. Am J Obstet Gynecol 2006; 195: 1629-1635
  16. Tovar A, Must A, Ber