Journals / Gülhane Tıp Dergisi / 2012 / Cilt: 54 - Sayı: 4

Food dependent exercise-induced anaphylaxis: A case report

Gıda ile ilişkili egzersiz anafilaksisi: Olgu sunumu

Pages
320–322
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this case report, we present a case of wheat dependent exercise-induced anaphylaxis that occurred in a 39-year-old man.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Food dependent exercise induced anaphylaxis is a rare but potentially fatal disorder where a food-intake alone does not induce any symptoms.
📊
Key Findings & Data:The most frequent causative food is wheat and omega-5-gliadin is known to represent a major causative allergen.
💡
Conclusion & Impact:In this case report, we present a case of wheat dependent exercise-induced anaphylaxis that occurred in a 39-year-old man.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Food dependent exercise induced anaphylaxis is a rare but potentially fatal disorder where a food-intake alone does not induce any symptoms. Symptoms reveal typically generalized urticarial plaques and severe allergic reactions such as shock or hypotension. The most frequent causative food is wheat and omega-5-gliadin is known to represent a major causative allergen. The diagnosis of food dependent exercise induced anaphylaxis is established by skin prick test or spesific IgE antibodies assay against food allergens. In this case report, we present a case of wheat dependent exercise-induced anaphylaxis that occurred in a 39-year-old man.

Özet

Gıda alımına bağlı egzersizin neden olduğu anafilaksi, çok nadir fakat yaşamı tehdit edici bir hastalık olup, tek başına gıda alımı ile semptomlar ortaya çıkmaz. Bulgular kendini tipik olarak, yaygın ürtikeriyal plaklar ve şok veya hipotansiyon gibi şiddetli allerjik reaksiyonlar şeklinde gösterir. Kliniğe neden olan gıdalar arasında en sık neden buğday olup içerisindeki omega- 5-gliadinin hastalığa neden olan temel alerjen olduğu bilinmektedir. Gıda alımına bağlı egzersizin neden olduğu anafilaksinin tanısı deri prick testi veya gıda allerjenlerine yanıt olarak ortaya çıkan spesifik IgE ölçümü ile konur. Bu olgu bildirisinde, buğdaya bağlı egzersiz anafilaksisi gelişen 39 yaşındaki bir erkek hasta sunulmuştur.

🔖

Cite This Article

ŞENER, O., KARTAL, Ö., GÜLEÇ, M., BAYSAN, A., MUŞABAK, U. (2012). Food dependent exercise-induced anaphylaxis: A case report. Gülhane Tıp Dergisi, Cilt: 54 - Sayı: 4, 320–322. https://ajindex.com/articles/225370

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (9)

  1. Aihara Y, Takahashi Y, Kotoyori T, et al. Frequency of food-dependent, exercise-induced anaphylaxis in Japanese junior-high-school students. J Allergy Clin Immunol 2001; 108:1035–1039
  2. Robson-Ansley P, Toit GD. Pathophysiology, diagnosis and management of exercise-induced anaphylaxis. Curr Opin Allergy Clin Immunol. 2010;10(4):312-317
  3. Barg W, Wolanczyk-Medrala A, Obojski A, et al. Fooddependent exerciseinduced anaphylaxis: possible impact of increased basophil histamine releasability in hyperosmolar conditions. J Investig Allergol Clin Immunol 2008; 18:312–315
  4. Wolanczyk-Medrala A, Barg W, Gogolewski G, et al. Influence of hyperosmotic conditions on basophil CD203c upregulation in patients with fooddependent exercise-induced anaphylaxis. Ann Agric Environ Med 2009;16:301–304
  5. Hultman E, Sahlin K. Acid-base balance during exercise. Exerc Sport Sci Rev 1980; 8:41–128
  6. Katsunuma T, Iikura Y, Akasawa A, et al. Wheat-dependent exercise-induced anaphylaxis: inhibition by sodium bicarbonate. Ann Allergy 1992;68:184–188
  7. Morita E, Matsuo H, Chinuki Y, Takahashi H, Dahlström J, Tanaka A. Food-dependent exercise-induced anaphylaxis -importance of omega-5 gliadin and HMW-glutenin as causative antigens for wheat-dependent exercise-induced anaphylaxis. Allergol Int. 2009;58(4):493-498
  8. Palosuo K, Varjonen E, Nurkkala J, et al. Transglutaminase- mediated crosslinking of a peptic fraction of omega-5 gliadin enhances IgE reactivity in wheat dependent, exercise-induced anaphylaxis. J Allergy Clin Immunol 2003; 111:1386–1392
  9. Jeukendrup AE, Vet-Joop K, Sturk A, et al. Relationship between gastrointestinal complaints and endotoxaemia, cytokine release and the acute-phase reaction during and after a long-distance triathlon in highly trained men. Clin Sci (Lond) 2000; 98:47–55.