Journals / Gülhane Tıp Dergisi / 2012 / Cilt: 54 - Sayı: 1

Selective intraarterial radionuclide radiotherapy of inoperable liver metastases with Yttrium-90 (Y-90) labeled microspheres in a patient with medullary thyroid carcinoma metastasis in the liver: first national administration

Medüller tiroid kanserli bir olguda inoperabl karaciğer metastazlarının Yttrium-90 (Y-90) işaretli mikroküreler ile selektif intraarteriyel radyonüklid tedavisi: ilk ulusal uygulama

Pages
57–61
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this study, the results of selective intraarterial radionuclide therapy performed with SIR-Spheres® for the first time in Turkey in a 32-year-old male patient with inoperable liver metastasis due to medullary thyroid carcinoma are presented.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Radioembolization of inoperable primary or metastatic liver cancers with Yttrium-90 (Y-90) labeled radiomicrospheres is a treatment modality with its efficacy established.
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Key Findings & Data:It is possible to administer curative doses of radiation to the tumor tissue while preserving normal liver parenchyma to a large extent with selective intraarterial radionuclide therapy performed with Y-90 labeled microspheres.
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Conclusion & Impact:In this study, the results of selective intraarterial radionuclide therapy performed with SIR-Spheres® for the first time in Turkey in a 32-year-old male patient with inoperable liver metastasis due to medullary thyroid carcinoma are presented.
🔬Design:Research Article
📍Scope:2008 Verileri
⚙️Variables:Karaciğer neoplazmları · Neoplazm metastazı · Radyoizotoplar

Abstract

Radioembolization of inoperable primary or metastatic liver cancers with Yttrium-90 (Y-90) labeled radiomicrospheres is a treatment modality with its efficacy established. It is possible to administer curative doses of radiation to the tumor tissue while preserving normal liver parenchyma to a large extent with selective intraarterial radionuclide therapy performed with Y-90 labeled microspheres. Selective intraarterial radionuclide therapy with SIRSpheres ® was approved by Turkish Ministry of Health for the treatment of inoperable liver cancers in April 2008. In this study, the results of selective intraarterial radionuclide therapy performed with SIR-Spheres® for the first time in Turkey in a 32-year-old male patient with inoperable liver metastasis due to medullary thyroid carcinoma are presented.

Özet

Yttrium-90 (Y-90) işaretli mikroküreler ile inoperabl primer veya metastatik karaciğer kanserlerinin radyoembolizasyonu, etkinliği kanıtlanmış bir tedavi yöntemidir. Y-90 işaretli mikroküreler ile yapılan selektif intraarteriyel radyonüklid tedavi işleminde normal karaciğer parankimi büyük oranda korunurken, tümör dokusuna küratif dozda radyoterapi uygulamak mümkün olmaktadır. Y-90 işaretli mikroküreler (SIR-Spheres®) ile selektif intraarteriyel radyonüklid tedavi inoperabl karaciğer kanserlerinde kullanılmak üzere Nisan 2008’de T.C. Sağlık Bakanlığı tarafından ruhsatlandırılmıştır. Bu çalışmada, medüller tiroid kanserine bağlı inoperabl karaciğer metastazlı 32 yaşındaki bir olguda, SIR-Spheres® ile Türkiye’de ilk kez uygulanan selektif intraarteriyel radyonüklid tedavi sonuçları sunulmaktadır.

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Cite This Article

ARSLAN, N., ÜSTÜNSÖZ, B., ALAGÖZ, E., UĞUREL, Ş., ÖZTÜRK, E., TUFAN, T., ÖZGÜVEN, M. A. (2012). Selective intraarterial radionuclide radiotherapy of inoperable liver metastases with Yttrium-90 (Y-90) labeled microspheres in a patient with medullary thyroid carcinoma metastasis in the liver: first national administration. Gülhane Tıp Dergisi, Cilt: 54 - Sayı: 1, 57–61. https://ajindex.com/articles/225358

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