Journals / Gülhane Tıp Dergisi / 2013 / Cilt: 55 - Sayı: 1

Kolorektal kanser için rezeke edilen spesmenlerde lenf nodu sayısını etkileyen faktörler

Factors affecting the number of lymph nodes in specimens resected for colorectal cancer

Pages
7–13
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Maximal attention should be paid while doing oncologic surgery and should be paid to the total number of lymph nodes retrieved.

📌 3 Key Takeaways

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Objective & Hypothesis:Adequate lymph node evaluation is required for proper staging of colorectal cancer, and the number of lymph nodes examined is associated with survival.
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Key Findings & Data:In this study, we aimed to evaluate the factors affecting the number of lymph nodes retrieved from specimens of patients operated for colorectal cancer.
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Conclusion & Impact:Maximal attention should be paid while doing oncologic surgery and should be paid to the total number of lymph nodes retrieved.
🔬Design:Research Article
📍Scope:2002 Verileri
⚙️Variables:Domain Parameters

Abstract

Adequate lymph node evaluation is required for proper staging of colorectal cancer, and the number of lymph nodes examined is associated with survival. In this study, we aimed to evaluate the factors affecting the number of lymph nodes retrieved from specimens of patients operated for colorectal cancer. Medical records of 320 consecutive patients with colorectal cancer were evaluated retrospectively whom had curative resection between 2002 and 2007. Variables such as age, gender, tumor localization, depth of tumor invasion, number of lymph nodes retrieved, specimen length, stage and grade of disease, type of surgery, primary/recurrence disease’ presence of preoperative chemo radiotherapy (CRT), surgeon, staff surgeon, pathologist, and staff pathologist were recorded and the results were evaluated statistically. Mean number of lymph nodes retrieved was 14.98 (0 to 129) and mean metastatic lymph node number was 2.37(0-25). Tumor localization, staging, primary/recurrence disease, length of specimen, type of operation, pathologist (resident pathologist), staff pathologist, staff surgeon, presence of CRT, affected statistically significiant in terms of lymph nodes harvested (p≤0.05). The hypothesis that disease recurrence occurred due to inaccurate staging. Maximal attention should be paid while doing oncologic surgery and should be paid to the total number of lymph nodes retrieved.

Özet

Kolorektal kanserlerin uygun evrelendirilmesi için yeterli lenf nodu değerlendirilmesi önemlidir ve elde edilen lenf nodu sayısı survival ile ilişkilidir. Bu çalışmada biz kolorektal kanser nedeniyle opere edilen hastaların patoloji örneklerinden elde edilen lenf nodu sayısını etkileyen faktörleri değerlendirmeyi amaçladık. 2002-2007 yılları arasında kolorektal kanser nedeniyle küratif rezeksiyon uygulanan 320 hastanın kayıtları retrospektif olarak değerlendirildi. Yaş, cinsiyet, tümör yeri, tümör derinliği, elde edilen lenf nodu sayısı, patoloji örneklerinin uzunluğu, evre, grade, cerrahi tipi, primer veya rekürrens durumu, preoperatif kemoradyoterapi varlığı, cerrah, uzman cerrah, patolog, uzman patolog kayıtları girildi ve sonuçlar istatistiksel olarak değerlendirildi. Ortalama 14,98(0-129) lenf nodu ve ortalama 2,37(0-25) metastatik lenf nodu elde edildi. Tümör yeri, evre, primer/rekürrens, patoloji örneklerinin uzunluğu, cerrahi tipi, patolog(makroskopist), uzman patolog, uzman cerrah, kemoradyoterapi varlığı istatistiksel olarak anlamlı şekilde çıkarılan lenf nodu sayısını etkiledi (p≤0.05). Hastalığın rekürrensi doğru olmayan evreleme ile ilişkilidir. Onkolojik cerrahi yaparken maksimum dikkat harcamak ve yeterli lenf nodu sayısı elde etmek gereklidir.

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Cite This Article

ÖZERHAN, İ. H., ERSÖZ, N., YAĞCI, G., CAN, M. F., ALTINER, Ö., ÖZTÜRK, E., KURT, B., HARLAK, A., DURAN, E., PEKER, Y., ÇETİNER, S. (2013). Kolorektal kanser için rezeke edilen spesmenlerde lenf nodu sayısını etkileyen faktörler. Gülhane Tıp Dergisi, Cilt: 55 - Sayı: 1, 7–13. https://ajindex.com/articles/225349

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