Journals / Gülhane Tıp Dergisi / 2014 / Cilt: 56 - Sayı: 2

Cerebral Venous Sinus Thrombosis; Analysis Of 17 Cases

Serebral Venöz Sinüs Trombozu; 17 Olgunun Analizi

Pages
102–106
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Anticoagulant therapy is the first-line treatment for cerebral venous sinus thrombosis because of its efficacy and safety.

📌 3 Key Takeaways

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Objective & Hypothesis:Cerebral venous sinus thrombosis (CVT) is a disease that is difficult to diagnose because of large variability of clinical symptoms and signs.
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Key Findings & Data:The demographic characteristics, initial symptoms and signs, clinical features, etiologies, imaging findings and treatments were retrospectively reviewed in the 17-patients accepted to our hospital between May-2003 and January-2011 with Cerebral Venous Thrombosis diagnosed by cranial magnetic resonance imaging and magnetic resonance venography.
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Conclusion & Impact:Anticoagulant therapy is the first-line treatment for cerebral venous sinus thrombosis because of its efficacy and safety.
🔬Design:Review & Systematic Survey
📍Scope:2003 Verileri
⚙️Variables:Domain Parameters

Abstract

Cerebral venous sinus thrombosis (CVT) is a disease that is difficult to diagnose because of large variability of clinical symptoms and signs. Poor prognosis may occur due to late diagnosis. The demographic characteristics, initial symptoms and signs, clinical features, etiologies, imaging findings and treatments were retrospectively reviewed in the 17-patients accepted to our hospital between May-2003 and January-2011 with Cerebral Venous Thrombosis diagnosed by cranial magnetic resonance imaging and magnetic resonance venography. The patients followed in our clinic with a diagnosis of cerebral venous thrombosis were 9-female and 8-men. All of the patients complained from headache, eight of the patients had epileptic seizures, six of patients had weakness and/or a complaint of numbness. Evaluation of etiologic factors revealed that CVT developed after pregnancy in three patient, after oral contraceptives in three patient. As the most common neurological examination findings during the first applicant were papillae edemas in 13 patients, 6 patients had motor deficits, sixth cranial nerve involvement was detected in 3 patients. All the patients were diagnosed with cerebral venous thrombosis were managed by anticoagulation therapy. One of our patients died. Although SVT is a rare disease, patient admitted with severe headaches and papilledema, epileptic seizure, and with prone to thrombosis, it should be considered. Early diagnosis is very important for CVT and anticoagulant, thrombolytic, antiepileptic and etiologic treatments should be done. Anticoagulant therapy is the first-line treatment for cerebral venous sinus thrombosis because of its efficacy and safety.

Özet

Serebral venöz tromboz (SVT), klinik semptom ve bulgularının çeşitliliği nedeniyle tanı konulması zor ve tanısı geç kalındığında dramatik bir hastalıktır.Mayıs 2003 - Ocak 2011 tarihleri arasında yatışı yapılan, kranial MRG ve MRV ile SVT tanısı kesinleşmiş 17 hastanın demografik özellikleri, başlangıç semptom ve bulguları, klinik özellikleri, etiyolojisi, görüntüleme bulguları ve tedavileri retrospektif olarak değerlendirildi.Serebral venöz trombozu tanısı ile kliniğimizde takip edilen hastaların 9'u kadın, 8'i erkekti. Olguların hepsinde baş ağrısı, 8'inde epileptik nöbet, 6'sında güçsüzlük ve/veya uyuşukluk yakınması mevcuttu. Hastalarda etiyolojik faktörler değerlendirildiğinde 3'ünde gebelik, 3'ünde oral kontraseptif kullanımı mevcuttu. İlk başvuru esnasında hastalarda en sık rastlanan nörolojik muayene bulgusu 13 hastayla papil ödemiyken, 6 hastada motor defisit, 3 hastada 6. kranial sinir tutulumu saptandı. Serebral venöz trombozu tanısı konan hastaların hepsine antikoagulan tedavi uygulanmıştır. Bir hastamız ex olmuştur.SVT nadir görülen bir hastalık olsa da; şiddetli baş ağrısı ve papil ödemi olan, epileptik nöbet ile gelen ve potansiyel olarak tromboza yatkın olabilecek olgularda akla getirilmelidir. Erken tanı önemli olup antikoagülan, trombolitik tedavi, antiepileptik ve etiyolojiye yönelik tedaviler yapılmalıdır. Bu tedaviler arasında antikoagülan tedavi etkili ve güvenli bir tedavi şeklidir.

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Cite This Article

AKGÜN, H., ÖZ, O., TAŞDEMİR, S., ALAY, S., YÜCEL, M., AKGÜN, V., GÖKÇİL, Z., ODABAŞI, Z., DEMİRKAYA, Ş. (2014). Cerebral Venous Sinus Thrombosis; Analysis Of 17 Cases. Gülhane Tıp Dergisi, Cilt: 56 - Sayı: 2, 102–106. https://ajindex.com/articles/225301

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