Journals / Gülhane Tıp Dergisi / 2015 / Cilt: 57 - Sayı: 7

Treatment outcomes and associated factors among tuberculosis patients in Southwest Ethiopia

Pages
397–407
DOI
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⚡ TL;DR(Too Long; Didn't Read)

Male gender, age greater than 35 years, smear negative and extra-pulmonary tuberculosis, retreatment with anti-tuberculosis medications, rural residence, being at prison, TB-HIV co-infection without co-trimoxazole preventive therapy and antiretroviral therapy were known to be independent predictors of poor treatment outcomes.

📌 3 Key Takeaways

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Objective & Hypothesis:The aim of this study is to assess treatment outcome and associated factors among tuberculosis patients in Southwest Ethiopia.
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Key Findings & Data:Data were collected from patients' follow up record and analyzed using SPSS version 16.0(Chicago: SPSS Inc., 2007).
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Conclusion & Impact:Male gender, age greater than 35 years, smear negative and extra-pulmonary tuberculosis, retreatment with anti-tuberculosis medications, rural residence, being at prison, TB-HIV co-infection without co-trimoxazole preventive therapy and antiretroviral therapy were known to be independent predictors of poor treatment outcomes.
🔬Design:Modeling & Simulation
📍Scope:2007 Verileri
⚙️Variables:Domain Parameters

Abstract

The aim of this study is to assess treatment outcome and associated factors among tuberculosis patients in Southwest Ethiopia. A five year general retrospective cohort was employed. Data were collected from patients' follow up record and analyzed using SPSS version 16.0(Chicago: SPSS Inc., 2007). P-value 0.05 was considered statistically significant. In the multivariate logistic regression model, age range of (35-44.9 years (AOR=6.5, 95% CI: 3.2-13.4),45-54.9 years (AOR=12.4,95% CI: 5.926.2),55-64.9 years (AOR=26.9, 95% CI:11.3-64.2) and >=65 years (AOR=25.93, 95% CI: 6.9-98.3); male gender (AOR=2.9, 95% CI: 1.9-4.5); rural residence (AOR=3.07, 95% CI: 2.08-4.53);being at prison(AOR=2.67,95% CI: 1.11-6.37);retreatment with antituberculosis medications (AOR=1.9, 95% CI: 1.25-2.89);smear negative tuberculosis (AOR=6.7,95% CI: 4.2-10.7); extra-pulmonary tuberculosis (AOR=5.2, 95% CI: 3.1- 8.7); TB-HIV co-infected patients without co-trimoxazole preventive therapy (AOR=58.6, 95% CI: 6.7-507.8); TB-HIV co-infected patients without antiretroviral treatment(AOR=10.5, 95% CI: 1.4-77.5) were identified as independent risk factors for poor treatment outcomes in the current study. Treatment outcome among tuberculosis patients was satisfactory in the study area. Male gender, age greater than 35 years, smear negative and extra-pulmonary tuberculosis, retreatment with anti-tuberculosis medications, rural residence, being at prison, TB-HIV co-infection without co-trimoxazole preventive therapy and antiretroviral therapy were known to be independent predictors of poor treatment outcomes.

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Cite This Article

ABEBE, T., ANGAMO, M. T. (2015). Treatment outcomes and associated factors among tuberculosis patients in Southwest Ethiopia. Gülhane Tıp Dergisi, Cilt: 57 - Sayı: 7, 397–407. https://ajindex.com/articles/225293

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References (13)

  1. World Health Organization. WHO report. Global tuberculosis control: epidemiology, strategy, financing. WHO/HTM/ TB/2008.393. Geneva, Switzerland: WHO, 2008
  2. World Health Organization. WHO report. Global tuberculosis control: epidemiology, strategy, financing. WHO/HTM/ TB//2012.6.). Geneva, Switzerland: WHO, 2012
  3. Castelnuovo B. A review of compliance to anti tuberculosis treatment and risk factors for defaulting treatment in Sub Saharan Africa. African health sciences. 2010;10(4):320-4
  4. Collins BN. Assessing the outcome of tuberculosis treatment in the Cameroon Baptist convention health board tuberculosis treatment centers. Sweden: Umea; 2011; 27-29
  5. Pefura Yone EW, Kengne AP, Kuaban C. Incidence, time and determinants of tuberculosis treatment default in Yaounde, Cameroon: a retrospective hospital registerbased cohort study. BMJ Open. 2011;1(2):e000289
  6. Amuha, M. G. Kutyabami, P. Kitutu, F. E. Odoi-Adome, R. Kalyango, N. J. Non-adherence to anti-TB drugs among TB/HIV co-infected patients in Mbarara Hospital Uganda: prevalence and associated factors. African health sciences. 2009;9 (1):8-15
  7. Weiguo Xu, Wei Lu, Yang Zhou, Limei Zhu, Hongbing Shen, Wang. J. Adherence to anti-tuberculosis treatment among pulmonary tuberculosis patients: a qualitative and quantitative study. BMC Health. 2009;9(169)
  8. Bronner LE, Podewils LJ, Peters A, Somnath P, Nshuti L, Van der Walt M, et al. Impact of community tracer teams on treatment outcomes among tuberculosis patients in South Africa. BMC Public Health. 2012;12(621)
  9. Vasankari T, Holmstrom P, Ollgren J, Liippo K, Kokki M, Ruutu P. Risk factors for poor tuberculosis treatment outcome in Finland: a cohort study. BMC Public Health. 2007;7:291
  10. Takarinda KC, Harries AD, Srinath S, Mutasa-Apollo T, Sandy C, Mugurungi O. Treatment outcomes of adult patients with recurrent tuberculosis in relation to HIV status in Zimbabwe: a retrospective record review. BMC Public Health. 2012;12(124)
  11. Sanchez M, Bartholomay P, Arakaki-Sanchez D, Enarson D, Bissell K, Barreira D, et al. Outcomes of TB treatment by HIV status in national recording systems in Brazil, 2003-2008. Plos One. 2012;7(3):e33129
  12. Gloria Akosua Ansa JDW, Kamran S,Xiaolin W. Assessing the impact of TB/HIV services integration on TB treatment outcomes and their relevance in TB/HIV monitoring in Ghana. BioMed Central. 2012;122-31
  13. Tansuphasawadikul S, Saito W, Kim J, Phonrat B, Dhitavat J, Chamnachanan S, et al. Outcomes in HIV-in