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Journals / Gülhane Tıp Dergisi / 2016 / Cilt: 58 - Sayı: 3

Seropositivity of anti-toxocara canis IgG in fibromyalgia patients

Fibromiyalji Hastalarında Anti-Toxocara canis IgG Seropozitifliği

Mehmet Burak SELEK
ORHAN BAYLAN
Mustafa ÖZYURT
Alparslan Bayram ÇARLI
Pages
229–232
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Our findings may be a sign of a possible role of toxocariasis in the etiology of FM, but needs to be investigated by case-control studies with larger populations

📌 3 Key Takeaways

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Objective & Hypothesis:Toxocariasis is a helminthic zoonosis caused by larval stages of Toxocara canis (T. canis), the roundworms of dogs.
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Key Findings & Data:We carried out a study in order to evaluate the T. canis seropositivity in FM patients.91 patients with FM were recruited from the Physical and Rehabilitation Medicine outpatient clinic.
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Conclusion & Impact:Our findings may be a sign of a possible role of toxocariasis in the etiology of FM, but needs to be investigated by case-control studies with larger populations
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Toxocariasis is a helminthic zoonosis caused by larval stages of Toxocara canis (T. canis), the roundworms of dogs. The prevalence of fibromyalgia (FM) is found higher in patients with Lyme disease, HIV, hepatitis B (HBV) and C viruses (HCV) infections. However, a possible relationship between T. canis infection and FM has not been reported previously in the literature. We carried out a study in order to evaluate the T. canis seropositivity in FM patients.91 patients with FM were recruited from the Physical and Rehabilitation Medicine outpatient clinic. Blood samples were obtained to determine eosinophil and total IgE levels with the ELISA method using the Toxocara-IgG ELISA kit to detect antibodies against the excretory/secretory antigen of the T. canis larvae.11 of the FM patients out of 91 (12,08%) had positive test results for T. canis seropositivity. We have found negative correlation between seropositivity and education level, daily hand washing habit. Having a dog as a pet and the duration of owning also increased prevalence. Our findings may be a sign of a possible role of toxocariasis in the etiology of FM, but needs to be investigated by case-control studies with larger populations

Özet

Toksokariyazis, köpeklerin yuvarlark kurtları olarak bilinen Toxocara canis'in (T. canis) larva formlarının denen olduğu helmintik bir zoonozdur. Fibromiyalji (FM) prevalansı, HIV, hepatit B ve C virüsü (HBV ve HCV) enfeksiyonları ile Lyme hastalığı olan bireylerde daha yüksektir. Ancak literatürde daha önce T. canis ile FM arasında olası bir ilişki belirtilmemiştir. Bu çalışma FM hastalarında T. canis seropozitifliğini belirlemeyi amaçlamaktadır.Çalışmaya, Fizik Tedavi ve Rehabilitasyon kliniğinden 91 FM hastası dahil edilmiştir. Toplanan kan örneklerinde eozinofil sayısını belirlenmiş ve Toxocara-IgG ELISA kiti kullanılarak T. canis lavrasından salınan/salgılanan antijenlere karşı üretilen antikorlar araştırılmıştır. 91 FM hastasından 11'inde (%12,08) T. canis antijeni pozitif bulunmuştur. Çalışmamızda, seropozitiflik ile eğitim düzeyi, günlük el yıkama alışkanlığı arasında negatif bir korelasyon bulunmuştur. Evcil hayvan olarak köpeğe sahip olma durumu ile sahip olma süresi de prevalansı arttırmıştır. Bulgularımız toksokariyazis ile FM etiyolojisi ile arasında olası bir ilişkiyi göstermekle birlikte, daha geniş hasta gruplarında vaka kontrollü çalışmalara da ihtiyaç duyulmaktadır

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Cite This Article

SELEK, M. B., BAYLAN, O., ÖZYURT, M., ÇARLI, A. B. (2016). Seropositivity of anti-toxocara canis IgG in fibromyalgia patients. Gülhane Tıp Dergisi, Cilt: 58 - Sayı: 3, 229–232. https://ajindex.com/articles/225262

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