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Journals / Harran Üniversitesi Tıp Fakültesi Dergisi / 2015 / Cilt: 12 - Sayı: 2

Assessment Of Mean Platelet Volume In Patients With Severe Obstructive Sleep Apnea

Ağır Obstrüktif Uyku Apne Sendromlu Hastalarda Ortalama Trombosit Hacminin Değerlendirilmesi

Zafer Hasan Ali SAK
Funda YALÇIN
Ayşegül Öney KURNAZ
Mehmet GENCER
İrfan ESER
Şamil GÜNAY
Pages
206–210
Publication Date
2015-08-30
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Unlike previous studies, these findings suggest that MPV isnot associated with the severity of OSAS and OSAS does not directly affect the platelet activity

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: In this study we aimed to evaluate the mean platelet volume (MPV) and Plateletcrit (PCT) associated with blood coagulability in patients with severe obstructive sleep apnea syndrome (OSAS).
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Key Findings & Data:Materials And Methods: The polysomnography recordings of 98 patients admitted to the sleep laboratory before September 2013 were retrospectively evaluated.
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Conclusion & Impact:Unlike previous studies, these findings suggest that MPV isnot associated with the severity of OSAS and OSAS does not directly affect the platelet activity
🔬Design:Research Article
📍Scope:2013 Verileri
⚙️Variables:Tıkayıcı Uyku Apne · Trombosit Sayısı · Trombosit aktivasyonu

Abstract

Objective: In this study we aimed to evaluate the mean platelet volume (MPV) and Plateletcrit (PCT) associated with blood coagulability in patients with severe obstructive sleep apnea syndrome (OSAS). Materials And Methods: The polysomnography recordings of 98 patients admitted to the sleep laboratory before September 2013 were retrospectively evaluated. All cases were grouped according to their AHI value as AHI <5 / h (n = 48) Group A (control) and AHI ≥ 30 / hour and Group B (n = 50). MPV and PCT (plateletcrit) was measured using an automatic blood cell counter. Polysomnographic findings, demographic data and blood parameters were compared. Results: No significant differences were found between Aand B groups with respect to PCT (0.218±0.06 vs. 0.212±0.05, p=0.66) and MPV (7.17±0.98 vs. 7.54±1.21fL, p=0.66). In severe OSAS group, MPV and PCT werenot correlated with AHİ (r=0.37, p=0.801 and r=0.61, p=0.624). Conclusion: MPV and PCT levels werenot higher in severe OSAS group compared to the control group. Unlike previous studies, these findings suggest that MPV isnot associated with the severity of OSAS and OSAS does not directly affect the platelet activity

Özet

Amaç: Bu çalışmada ağır tıkayıcı uyku apne sendromlu (OSAS) hastalarda kan koagülabilitesiyle ilişkili Ortalama Trombosit Hacmini (MPV) ve Plateletcriti (PCT) değerlendirmeyi amaçladık. Gereç ve yöntemler: Uyku ünitesinde Eylül 2013 öncesi polisomnografi yapılan 98 hastanın kayıtları retrospektif değerlendirildi. Tüm olgular apne-hipopne indeksine(AHİ) göre AHİ <5 / saat (s=48) AGrubu (kontrol), AHİ ≥ 30 / saat ile B Grubu (s = 50) şeklinde gruplandırıldı. MPVve PCT(plateletcrit) otomatik bir kan hücresi sayacı kullanılarak ölçüldü. Polisomnografik bulgularla, demografik ve kan parametreleri karşılaştırıldı. Bulgular: A ve B grupları arasında MPV (7.17±0.98 karşılık 7.54±1.21fL, p=0.66) ve PCT (0.218±0.06 karşılık 0.212±0.05, p=0.66) açısından anlamlı farklılık bulunamadı. Ağır OSAS grubunda MPV, PCT ile AHİ parametreleri arasında anlamlı korelasyon saptanmadı(r=0.37, p=0.801 ve r=0.61, p=0.624). Sonuç: MPV ve PCT değerlerinde ağır OSAS'lı hastalarda kontrole göre anlamlı yükseklik bulunmadı.Bu bulgular yapılan ilk çalışmaların aksine MPV'nin OSAS'ın ağırlığıyla ilişkili bir parametre olmadığı ve OSAS'ın doğrudan trombosit aktivitesini etkilemediğini düşündürmektedir.

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Cite This Article

SAK, Z. H. A., YALÇIN, F., KURNAZ, A. Ö., GENCER, M., ESER, İ., GÜNAY, Ş. (2015). Assessment Of Mean Platelet Volume In Patients With Severe Obstructive Sleep Apnea. Harran Üniversitesi Tıp Fakültesi Dergisi, Cilt: 12 - Sayı: 2, 206–210. https://ajindex.com/articles/22513

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