Journals / Gülhane Tıp Dergisi / 2012 / Cilt: 54 - Sayı: 2

Akciğer kanserli hastalarda kemoterapinin yaşam kalitesi üzerine etkisi

The effect of chemotherapy on quality of life in patients with lung carcinoma

Pages
136–141
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Pain negatively affected all areas of quality of life; indeed, the quality of life of the patients decreased as pain increased.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The aim of the present study was to determine the effect of chemotherapy on the quality of life of patients with lung carcinoma.
📊
Key Findings & Data:Fifty patients who were receiving chemotherapy between January 2006 and January 2007 were included in the study.
💡
Conclusion & Impact:Pain negatively affected all areas of quality of life; indeed, the quality of life of the patients decreased as pain increased.
🔬Design:Survey & Empirical Study
📍Scope:2006 Verileri
⚙️Variables:Domain Parameters

Abstract

The aim of the present study was to determine the effect of chemotherapy on the quality of life of patients with lung carcinoma. Fifty patients who were receiving chemotherapy between January 2006 and January 2007 were included in the study. The quality of life questionnaire (QLQ C-30), lung cancer specific module (LC-13) of the European Organization for Research and Treatment of Cancer (EORTC), and visual analog scale (VAS) were used in data collection. Chemotherapy resulted in worsening of social functioning, as well as dyspnea, constipation, and alopecia, whereas coughing improved. The economic status of the patients became worse compared to the first chemotherapy period (p<0.05). Chemotherapy led to a decrease in physical and social functioning in the patients with non-small cell lung cancer, and an increase in fatigue, nausea, insomnia, and constipation. No statistical significance was observed between the presence of metastases and quality of life. Pain negatively affected all subscales of the quality of life. Although no relationship was observed between the quality of life and sociodemographic characteristics, such as age and educational status, gender affected the quality of life, and the role, emotional, and cognitive functioning of the quality of life were worse in females compared to males. Sociodemographic characteristics had no significant impact on the quality of life of the patients with lung cancer. Pain negatively affected all areas of quality of life; indeed, the quality of life of the patients decreased as pain increased.

Özet

Bu çalışmada akciğer kanserli hastalarda kemoterapinin yaşam kalitesi üzerine etkilerinin belirlenmesi amaçlanmıştır. Araştırmaya Ocak 2006 ile Ocak 2007 yılları arasında kemoterapi tedavisi gören 50 hasta alındı. Veri toplama aracı olarak Avrupa Kanser Araştırma ve Tedavi Organizasyonu (EORTC) Yaşam Kalitesi Anketi (QLQ C-30) ve akciğer kanseri modülü (LC-13) ile görsel analog ölçeği (VAS) kullanıldı. Kemoterapi tedavisi ile birlikte sosyal fonksiyonda azalma ve dispne, konstipasyon, alopeside artma ve öksürükte azalma saptandı. Olguların ekonomik durumları da birinci kemoterapi dönemindekine göre daha kötü bulundu (p<0.05). Kemoterapi tedavisi ile birlikte küçük hücre dışı akciğer kanserli hastalarda fiziksel fonksiyon ve sosyal fonksiyon alanları azalmış, yorgunluk, bulantı, uykusuzluk, konstipasyon da artmıştır. Metastaz varlığı ile yaşam kalitesi arasında istatistiksel olarak anlamlı bir farklılık yoktu. Ağrı yaşam kalitesinin bütün alanlarını negatif yönde etkilemektedir. Yaş, eğitim durumu gibi sosyodemografik özelliklerle yaşam kalitesi arasında ilişki olmamakla birlikte, cinsiyet yaşam kalitesini etkilemektedir ve erkeklerde yaşam kalitesi rol fonksiyon, emosyonel fonksiyon ve kognitif fonksiyon alanları kadınlara göre daha iyidir. Akciğer kanserli hastalarda yaşam kalitesinin değerlendirilmesinde sosyodemografik özelliklerin anlamlı bir etkisi yoktur. Ağrı yaşam kalitesinin bütün alanlarını negatif yönde etkilemektedir ve olgularda ağrı arttıkça yaşam kaliteleri düşmektedir.

🔖

Cite This Article

ALTIPARMAK, O., ÜNSAL, İ., ALTIPARMAK, S., TATAR, D., HALİLÇOLAR, H., ANAR, C. M. (2012). Akciğer kanserli hastalarda kemoterapinin yaşam kalitesi üzerine etkisi. Gülhane Tıp Dergisi, Cilt: 54 - Sayı: 2, 136–141. https://ajindex.com/articles/224417

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (15)

  1. Wynder EL, Hoffman D. Smoking and lung cancer: scientific challenges and opportunities. Cancer Res 1994; 54: 5284-5285
  2. Göksel T, Güzelant A. Akciğer kanserinde yaşam kalitesi değerlendirmeleri. In: Hastürk S, Yüksel M (eds). Akciğer Kanseri. İstanbul: Bilmedya Grup, 2000: 359-375
  3. Given CW, Given BA, Stommel M. The impact of age, treatment, and symptoms on the physical and mental health of cancer patients. A longitudinal perspective. Cancer 1994; 74 (Suppl): 2128-2138
  4. Hajiro T, Nishimura K, Tsukino M, Ikeda A, Koyama H, Izumi T. Comparison of discriminative properties among disease spesific questionnaires for measuring health-related quality of life in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1998; 157: 785-790
  5. Gültekin Z, Pınar G, Pınar T ve ark. Akciğer kanserli hastaların yaşam kaliteleri ve sağlık bakım hizmet beklentileri. Uluslararası Hematoloji Onkoloji Dergisi 2008; 15: 99-106
  6. Saxena S, Orley J; on behalf of the WHOQOL Group. Quality of life assessment: The world health organization perspective. Eur Psychiatry 1997; 12 (Suppl 3): 263S-266S
  7. Ware JE Jr. The status of health assessment 1994. Annu Rev Public Health 1995; 16: 327-354
  8. Guzelant A, Goksel T, Ozkok S, Tasbakan S, Aysan T, Bottomley A. The European Organization for Research and Treatment of Cancer QLQ-C30: an examination into the cultural validity and reliability of the Turkish version of the EORTC QLQ-C30. Eur J Cancer Care (Engl) 2004; 13: 135-144
  9. Griffin JP, Nelson JE, Koch KA, et al. American College of Chest Physicians. End-of-life care in patients with lung cancer. Chest 2003; 123 (Suppl 1): 312S-331S
  10. Ganz PA, Schag CA, Cheng HL. Assessing the quality of life a study in newly-diagnosed breast cancer patients. J Clin Epidemiol 1990; 43: 75-86
  11. Kvale PA, Simoff M, Prakash UB. American College of Chest Physicians. Lung cancer. Palliative care. Chest 2003; 123 (Suppl 1): 284S-311S
  12. Rustoen T, Moum T, Wiklund I, Hanested BR. Quality of life in newly diagnosed cancer patients. J Adv Nurs 1999; 29: 490-498
  13. Arslan S, Bölükbaş N. Kanserli hastalarda yaşam kalitesinin değerlendirilmesi Atatürk Üniversitesi HYO Dergisi 2003; 6: 38-47
  14. Pandey M, Sarita GP, Devi N, Thomas BC, Hussain BM, Krishan N. Distress, anxiety, and depression in cancer patients undergoing chemotherapy. World J Surg Oncol 2006; 4: 68
  15. Gralla RJ. Quality-of-life considerations in patients with advanced lung cancer: effect of topote