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Journals / Erciyes Medical Journal / 2017 / Cilt: 39 - Sayı: 4

Comparative Evaluation of Mediastinal Lymph Nodes in Non-small Cell Lung Cancer with Computed Tomography, 99mTc-MIBI SPECT, and Video-Mediastinoscopy

ÖMER ÖNAL
ÖMER FARUK DEMİR
Pages
154–159
DOI
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⚡ TL;DR(Too Long; Didn't Read)

The 99mTc-MIBI SPECT showed better results than CT with regard to positive and negative predictive values and accuracy.Conclusion: This study indicates that Tc99m-MIBI SPECT has a better diagnostic value than CT in detecting MLN metastases in NSCLC.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: The aim of this study is to evaluate the mediastinal lymph node (MLN) metastasis comparatively with Tc99m-MIBI SPECT scintigraphy, thoracic computed tomography (CT), and video-mediastinoscopy (VM) in the staging of non-small cell lung cancer (NSCLC).Materials and Methods: Forty consecutive patients (36 men, 4 women, average age 59.3 years) who were to undergo surgical treatment for NSCLC between June 2008 and June 2009 were included in this prospective study.
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Key Findings & Data:All patients underwent chest 99mTc-MIBI SPECT before VM.
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Conclusion & Impact:The 99mTc-MIBI SPECT showed better results than CT with regard to positive and negative predictive values and accuracy.Conclusion: This study indicates that Tc99m-MIBI SPECT has a better diagnostic value than CT in detecting MLN metastases in NSCLC.
🔬Design:Research Article
📍Scope:2008 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: The aim of this study is to evaluate the mediastinal lymph node (MLN) metastasis comparatively with Tc99m-MIBI SPECT scintigraphy, thoracic computed tomography (CT), and video-mediastinoscopy (VM) in the staging of non-small cell lung cancer (NSCLC).Materials and Methods: Forty consecutive patients (36 men, 4 women, average age 59.3 years) who were to undergo surgical treatment for NSCLC between June 2008 and June 2009 were included in this prospective study. All patients underwent chest 99mTc-MIBI SPECT before VM. SPECT results were evaluated visually and semi-quantitatively. Thoracotomy and MLN dissection were applied in patients who did not have MLN metastasis.Results: The MLN involvement was demonstrated in 6 patients via VM. 99mTc-MIBI SPECT correctly staged 5 out of 6 patients, and CT 2 out of 6 patients. The 99mTc-MIBI SPECT showed better results than CT with regard to positive and negative predictive values and accuracy.Conclusion: This study indicates that Tc99m-MIBI SPECT has a better diagnostic value than CT in detecting MLN metastases in NSCLC.

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Cite This Article

ÖNAL, Ö., DEMİR, Ö. F. (2017). Comparative Evaluation of Mediastinal Lymph Nodes in Non-small Cell Lung Cancer with Computed Tomography, 99mTc-MIBI SPECT, and Video-Mediastinoscopy. Erciyes Medical Journal, Cilt: 39 - Sayı: 4, 154–159. https://ajindex.com/articles/223482

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