Journals / Fırat Tıp Dergisi / 2014 / Cilt: 19 - Sayı: 3

Role of Surgery in Isolated Pulmonary Metastases with our Clinical Experience

Klinik Deneyimimiz ile İzole Pulmoner Metastaz Varlığında Cerrahinin Yeri

Pages
130–134
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Larger series are needed to find out the clear contribution of the number of metastases to survival.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Lung metastases must be consider in a different way compared with the others.
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Key Findings & Data:Material and Method: A total of 19 patients (11 females, 8 males; median age 45 years; range 21 to 68 years) who underwent pulmonary metastasectomy between years 2005 and 2013 were retrospectively reviewed.
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Conclusion & Impact:Larger series are needed to find out the clear contribution of the number of metastases to survival.
🔬Design:Review & Systematic Survey
📍Scope:2005 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: Lung metastases must be consider in a different way compared with the others. It is known that, in pulmonary metastasis, cases that had complete surgical resections have longer survival. In this study, we examined the role of surgery in metastatic lung lesions and contribution of the pulmonary metastasectomy to survival in the light of our clinical experience. Material and Method: A total of 19 patients (11 females, 8 males; median age 45 years; range 21 to 68 years) who underwent pulmonary metastasectomy between years 2005 and 2013 were retrospectively reviewed. Patients were classified according to age, gender, primary histology of tumor, disease-free interval, radiological ve intraoperative number of metastatic lesions, operative techniques, follow-up period. Results: Thoracotomy was performed to all patients except one who operated with videothoracoscopik surgery. Preoperative thorax computed tomographies were detected 64 metastatic nodules which were detected as 81 after the operations. The only complication was prolonged air leak and occured in 3 patients. Three patients were died in postoperative first year because of multipl metastases. Seven patients are following with variable metastatic lesions while the rest are following with disease-free. Conclusion: Pulmonary metastasectomy in selected patients that primary tumor is under control and suitable for surgery, is known to effect the survival positively. Thoracotomy and a careful palpation is still preferred mostly to detect the nodules which were not marked at thorax computed tomography. Larger series are needed to find out the clear contribution of the number of metastases to survival.

Özet

Amaç: Akciğer birçok malign tümörün en sık metastaz yaptığı organdır ve diğer sistemik metastazların aksine izole akciğer metastazında cerrahi yaklaşım birden fazla organ metastazı olan olgularla karşılaştırıldığında komplet cerrahi rezeksiyon sonrasında daha iyi sağkalım gösterebilmektedirler. Çalışmamızda pulmoner metastazlarda metastazektominin yeri ve sağ kalıma etkisi ile ilgili klinik deneyimimizi paylaşmayı amaçladık. Gereç ve Yöntem: Kliniğimizde sekiz yıllık süre içinde toplam 29 metastazektomi yapılmış 19 hastanın (11 kadın, 8 erkek; medyan yaş; 45) kayıtları retrospektif olarak incelendi. Hastalar yaş, cinsiyet, primer tümör patolojisi, hastalıksız geçen süre, radyolojik olarak ve cerrahi olarak tespit edilen metastatik lezyon sayısı, operasyon şekli ve izlem süreci göz önüne alınarak değerlendirildi. Bulgular: Video-yardımlı torakoskopik cerrahi (VATS) uyguladığımız periferik 1 cm çaplı bir lezyonu olan tek olgu dışında tüm vakalara torakotomi ile yaklaşıldı. Operasyon öncesi BT tetkikinde 64 adet metastatik lezyon saptanmasına rağmen, cerrahi sırasında toplam 81 metastatik lezyon rezeke edildi. Majör komplikasyon görülmedi, üç olguda uzamış hava kaçağı gelişti. Üç hastamız postoperatif bir yıl içinde yaygın metastaz ile kaybedilirken, yedi hastamız postoperatif 2-5 yıllık dönem içinde gelişen uzak metastazları ile geri kalan hastalar ise hastalıksız takip edilmektedir. Sonuç: Pulmoner lezyonlarda metastazektominin primer tümörü kontrol altında olan, cerrahiye uygun seçilmiş hasta grubunda sağkalımı olumu etkilediği bilinmektedir. Radyolojik olarak atlanan nodüller de gözönüne alındığında torakotomi ve dikkatli bir palpasyon halen tercih edilen cerrahi yöntemdir. Objektif bir değerlendirme yapmak için çok sayıda vaka içeren geniş metastazektomi serileri uygun olacaktır.

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Cite This Article

AKGÜL, A. G., MEHMETOĞLU, S. S., ÇABUK, D., ÖZBAY, S., SEZER, H. F., LİMAN, Ş. T., TOPÇU, S. (2014). Role of Surgery in Isolated Pulmonary Metastases with our Clinical Experience. Fırat Tıp Dergisi, Cilt: 19 - Sayı: 3, 130–134. https://ajindex.com/articles/223191

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