Journals / Ege Tıp Dergisi / 1999 / Cilt: 38 - Sayı: 2

Differantiation of the epithelial reticular cell in the young postnatal period of rat thymus

Genç postnatal dönem sıçan timusunda epitelyal retiküler hücre farklılaşması

Pages
69–73
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In addition, some epithelial cells became flattened and degenerated and changed to Hassalls corpuscles

📌 3 Key Takeaways

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Objective & Hypothesis:The differentiation pattern of epithelial reticular cells originating from endoderm were investigated according to cell types in the young postnatal rat thymus.
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Key Findings & Data:Five groups of Wistar type rat thymus were used in the study: 24, 48, 72 hours; 1 and 2 months.
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Conclusion & Impact:In addition, some epithelial cells became flattened and degenerated and changed to Hassalls corpuscles
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Timus bezi · Retikülositler · Sıçanlar

Abstract

The differentiation pattern of epithelial reticular cells originating from endoderm were investigated according to cell types in the young postnatal rat thymus. Five groups of Wistar type rat thymus were used in the study: 24, 48, 72 hours; 1 and 2 months. After routine procedure for the light microscope, the tissues were embedded in paraffin capsules and sectioned by Reichert OMU 2 ultratome. Sections were stained with H.E., PAS, Mallory Azan. As a result; it was observed that cortical epithelial reticular cells, which are stellate shaped connecting to each other with their long processes, matured with lymphocytic infiltration and differentiation. Some of them, promoting lymphocyte differentiation, developed into large epithelial reticular cells, which are located on vessel walls and medulla, forming cystic and intervillos cords. In addition, some epithelial cells became flattened and degenerated and changed to Hassalls corpuscles

Özet

Genç postnatal dönem sıçan timusunda, endodermal kökenli epitelyal retiküler hücrelerin farklılaşması ışık mikroskobu düzeyinde hücre tiplerinin tanımlanması yapılarak incelendi. 24, 48, 72 saatlik: 1 ve 2 aylık olmak üzere beş grup Wistar türü sıçan timusu kullanıldı. Rutin ışık mikroskobu takibinden sonra parafin kapsüle gömülerek, Reichert OMU 2 ultratomunda kesitleri alındı. H.E., PAS ve Mallory - Azan boyaları uygulandı. Sonuç olarak; kortikal epitelyal retiküler hücrelerin lenfosit infiltrasyonu ve farklılaşması ile birlikte gelişmelerini sürdürdüğü, yıldız biçimli şekilleriyle birbirlerine uzun uzantılarla tutunduğu tespit edildi. Bunların bazılarının lenfositlerin farklılaşmasını destekleyen, damar duvarlarında ve medullada yerleşim göstererek kistik ve intervillöz kordonlar oluşturan büyük epitelyal retiküler hücrelere farklılaştığı görüldü. Ayrıca medullada bazı epitelyal retiküler hücrelerin yassılaşarak dejenerasyon gösterip Hassall korpüsküllerine dönüştüğü izlendi

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Cite This Article

YURTSEVEN, E. M., UYSAL, A., AKTAN, A., YAVAŞOĞLU, A. (1999). Differantiation of the epithelial reticular cell in the young postnatal period of rat thymus. Ege Tıp Dergisi, Cilt: 38 - Sayı: 2, 69–73. https://ajindex.com/articles/223159