Journals / Ege Tıp Dergisi / 2004 / Cilt: 43 - Sayı: 2

Ursodeoxycholic acid treatment in acute hepatitis A virus infection-related cholestasis

Akut hepatit A virus infeksiyonuna bağlı kolestazda ursodeoksikolik asit tedavisi

Pages
127–129
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We conclude that ursodeoxycholic acid has a beneficial effect on the course of the acute hepatitis A virus infection-related cholestasis.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Ursodeoxycholic acid is a hydrophilic and non-toxic bile acid which is recognized as a main treatment for chronic cholestatic hepatitis.
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Key Findings & Data:In this case report, two children aged 5 and 12 years old with hepatitis A virus infection-related cholestasis were presented.
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Conclusion & Impact:We conclude that ursodeoxycholic acid has a beneficial effect on the course of the acute hepatitis A virus infection-related cholestasis.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Ursodeoksikolik asit · Hepatit A · Kolestaz

Abstract

Ursodeoxycholic acid is a hydrophilic and non-toxic bile acid which is recognized as a main treatment for chronic cholestatic hepatitis. In previously published studies ursodeoxycholic acid showed some beneficial effects on the course of acute viral hepatitis in adults. In this case report, two children aged 5 and 12 years old with hepatitis A virus infection-related cholestasis were presented. The clinical and laboratory manifestations were improved after one-month-ursodeoxycholic acid therapy in our patients. We conclude that ursodeoxycholic acid has a beneficial effect on the course of the acute hepatitis A virus infection-related cholestasis.

Özet

Ursodeoksikolik asit hidrofilik ve non-toksik bir safra asidi olup kronik kolestatik hepatitin ternel tedavisidir. Daha önceden yayınlanmış çalışmalarda akut viral hepatitin erişkinlerdeki seyri üzerinde bazı yararlı etkileri olduğu gösterilmiştir.Bu olgu bildirisinde, hepatit A virus infeksiyonuna bağlı kolestazı olan 5 ve 12 yaşlarında iki çocuk sunuldu. Hastalarımızda bir aylık ursodeoksikolik asit tedavisinden sonra klinik ve laboratuvar belirtileri düzeldi.Ursodeoksikolik asitin akut hepatit A virus infeksiyonuna bağlı kolestazın seyri üzerinde yararlı etkisi olduğu düşünüldü.

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Cite This Article

KASIRGA, H. E., AKİL, İ., COŞKUN, Ş., ÖZGÜVEN, A. A., KARAKOÇ, Z. (2004). Ursodeoxycholic acid treatment in acute hepatitis A virus infection-related cholestasis. Ege Tıp Dergisi, Cilt: 43 - Sayı: 2, 127–129. https://ajindex.com/articles/223023

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