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Journals / Düşünen Adam - Psikiyatri ve Nörolojik Bilimler Dergisi / 2019 / Cilt: 32 - Sayı: 4

Examination of neutrophil, platelet, and monocytelymphocyte ratios in adolescents with bipolar disorder-manic episode and depression

Mirac Baris USTA
Armagan ARAL
Abdullah BOZKURT
BERKAN ŞAHİN
Koray KARABEKİROĞLU
Pages
328–333
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Larger-scale studies are necessary to confirm these findings.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: Neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), and monocyte/lymphocyte ratio (MLR) are practical inflammation parameters.
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Key Findings & Data:Method: Forty-six patients with MDD and 43 patients with BD hospitalized between 2013 and 2017 and 40 HC were included in the study.
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Conclusion & Impact:Larger-scale studies are necessary to confirm these findings.
🔬Design:Research Article
📍Scope:2013 Verileri
⚙️Variables:Domain Parameters

Özet

Objective: Neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), and monocyte/lymphocyte ratio (MLR) are practical inflammation parameters. In bipolar disorder (BD) and major depressive disorder (MDD), these parameters were reported higher than in healthy controls (HC). We aim to compare NLR, PLR, MLR in HC and patients with MDD and BB-manic episode. Method: Forty-six patients with MDD and 43 patients with BD hospitalized between 2013 and 2017 and 40 HC were included in the study. White blood cell, neutrophil, lymphocyte, platelet, and monocyte numbers were entered retrospectively from complete blood counts made at the time of admission, and NLR, PLR, and MLR were calculated from these. Results: NLR and PLR were revealed higher in MDD than HC. NLR and neutrophil values were higher in BD than HC, and there was a positive correlation between NLR and hospitalization period of patients with BD. Conclusion: Findings of our study supported the inflammation hypothesis for MDD and BD in adolescents. Larger-scale studies are necessary to confirm these findings.

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Cite This Article

USTA, M. B., ARAL, A., BOZKURT, A., ŞAHİN, B., KARABEKİROĞLU, K. (2019). Examination of neutrophil, platelet, and monocytelymphocyte ratios in adolescents with bipolar disorder-manic episode and depression. Düşünen Adam - Psikiyatri ve Nörolojik Bilimler Dergisi, Cilt: 32 - Sayı: 4, 328–333. https://ajindex.com/articles/222549

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