Journals / Turkish Journal of Chemistry / 2006 / Cilt: 30 - Sayı: 2

Synthesis and Antifungal Properties of Some Benzimidazole Derivatives

Pages
223–228
Publication Date
2006-02-01
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Compounds 6 and 9 possessed activity comparable to fluconazole against C. albicans with a minimum inhibitory concentration of 12.5 m g/mL.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Some benzimidazole derivatives were synthesized and their in vitro antifungal activities were tested against Candida albicans, Candida glabrata and Candida krusei.
📊
Key Findings & Data:Some benzimidazole derivatives were synthesized and their in vitro antifungal activities were tested against Candida albicans, Candida glabrata and Candida krusei.
💡
Conclusion & Impact:Compounds 6 and 9 possessed activity comparable to fluconazole against C. albicans with a minimum inhibitory concentration of 12.5 m g/mL.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Benzimidazole · thiourea · antifungal

Abstract

Some benzimidazole derivatives were synthesized and their in vitro antifungal activities were tested against Candida albicans, Candida glabrata and Candida krusei. Compounds 6 and 9 possessed activity comparable to fluconazole against C. albicans with a minimum inhibitory concentration of 12.5 m g/mL.

Özet

Some benzimidazole derivatives were synthesized and their in vitro antifungal activities were tested against Candida albicans, Candida glabrata and Candida krusei. Compounds 6 and 9 possessed activity comparable to fluconazole against C. albicans with a minimum inhibitory concentration of 12.5 m g/mL.

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Cite This Article

KILCIGİL, G. A., ALTANLAR, N. (2006). Synthesis and Antifungal Properties of Some Benzimidazole Derivatives. Turkish Journal of Chemistry, Cilt: 30 - Sayı: 2, 223–228. https://ajindex.com/articles/220574

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