Journals / Çocuk Enfeksiyon Dergisi / 2009 / Cilt: 3 - Sayı: 2

Brusellaya bağlı trombositopenik purpura

Management of brucella-induced thrombocytopenic purpura

Pages
83–85
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The hematological consequences of brucellosis should always be kept in mind in the differential diagnosis of isolated thrombocytopenia in endemic areas.

📌 3 Key Takeaways

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Objective & Hypothesis:rucellar infections are still a major public health issue in Mediterranean countries.
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Key Findings & Data:Brucellosis may cause hematological abnormalities, particularly cytopenias.
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Conclusion & Impact:The hematological consequences of brucellosis should always be kept in mind in the differential diagnosis of isolated thrombocytopenia in endemic areas.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

rucellar infections are still a major public health issue in Mediterranean countries. Brucellosis may cause hematological abnormalities, particularly cytopenias. Severe thrombocytopenia leading to mucosal bleeding and purpuric rash is relatively infrequent. We herewith present three patients who were admitted with mucosal bleeding and purpura, and were finally diagnosed as brucellosis. The severe isolated thrombocytopenia, purpuric rash and compatible bone marrow findings on admission suggested the presumed diagnosis of ITP in all cases. All three patients received different treatment regimens and finally recovered without complications. There is no consensus regarding the management of brucella-induced thrombocytopenic purpura in the literature. The hematological consequences of brucellosis should always be kept in mind in the differential diagnosis of isolated thrombocytopenia in endemic areas.

Özet

Brusella enfeksiyonları Akdeniz ülkelerinde halen önemli bir halk sağlığı sorunudur. Brusellozis hematolojik anormalliklere, özellikle sitopenilere yol açabilir. Mukozal kanamaya ve purpurik döküntüye sebep olacak şekilde ciddi trombositopeni ise nadiren görülmektedir. Bu yazıda mukozal kanama ve purpura ile başvuran ancak sonrasında brusellozis tanısı konulan 3 hastamızı sunmak istedik. Tek başına olan ağır trombositopeni, purpurik döküntü ve uygun kemik iliği bulguları nedeniyle tüm vakalara öncelikle ITP tanısı konuldu. Her üç hasta farklı ilaç protokolleri ile tedavi edilmelerine rağmen komplikasyonsuz iyileştiler. Literatürde brusella enfeksiyonlarına bağlı trombositopenileri yaklaşım konusunda fikir birliği bulunmamaktadır. Endemik bölgelerde izole trombositopeninin ayırıcı tanısında brusella enfeksiyonları mutlaka araştırılmalıdır.

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Cite This Article

ÖZEN, M., ÖZGEN, Ü., GÜNGÖR, S. (2009). Brusellaya bağlı trombositopenik purpura. Çocuk Enfeksiyon Dergisi, Cilt: 3 - Sayı: 2, 83–85. https://ajindex.com/articles/220205

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References (1)

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