Journals / Ege Klinikleri Tıp Dergisi / 2020 / Cilt: 58 - Sayı: 3

The Effect of Nasopharyngeal Swab Positivity and Accompanying Chronic Disease on High Flow Nasal Cannula Oxygen Therapy

Nazofarengeal Sürüntü Pozitifliği ve Eşlik Eden Kronik Hastalığın Yüksek Akımlı Nazal Kanül Oksijen Tedavisine Etkisi

Pages
349–355
DOI
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⚡ TL;DR(Too Long; Didn't Read)

Results: It was found that nasopharyngeal swab positivity had a significant effect on the duration of high flow nasal cannula oxygen therapy administration, but it was ineffective in eliminating the need to connect to a ventilator.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: The aim of this study is to investigate the effect of swab positivity, concomitant chronic disease, and prematurity on response to treatment in pediatric patients with respiratory distress due to lower respiratory tract infection and receiving high flow oxygen therapy.
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Key Findings & Data:Materials and method: Pediatric patients admitted to our emergency department due to respiratory distress aged between 1 month and 9 years, who were diagnosed with lower respiratory tract infection and were treated with high flow nasal cannula oxygen therapy were included in this study.
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Conclusion & Impact:Results: It was found that nasopharyngeal swab positivity had a significant effect on the duration of high flow nasal cannula oxygen therapy administration, but it was ineffective in eliminating the need to connect to a ventilator.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: The aim of this study is to investigate the effect of swab positivity, concomitant chronic disease, and prematurity on response to treatment in pediatric patients with respiratory distress due to lower respiratory tract infection and receiving high flow oxygen therapy. Materials and method: Pediatric patients admitted to our emergency department due to respiratory distress aged between 1 month and 9 years, who were diagnosed with lower respiratory tract infection and were treated with high flow nasal cannula oxygen therapy were included in this study. Patient records were scanned retrospectively. Demographic data of the patients were reviewed. The patients were grouped as positive and negative ones according to nasopharyngeal swab positivity. The effects of diseases that cause respiratory distress, infectious agent, presence of concomitant chronic diseases, and history of preterm birth on response to treatment were investigated. Results: It was found that nasopharyngeal swab positivity had a significant effect on the duration of high flow nasal cannula oxygen therapy administration, but it was ineffective in eliminating the need to connect to a ventilator. It was found that the response to treatment was significantly reduced in the presence of chronic disease. Conclusions: The presence of chronic concomitant disease was found to be the most important factor in treatment unresponsiveness. For patients with chronic diseases, be prepared for invasive respiratory support.

Özet

Amaç: Bu çalışmanın amacı, alt solunum yolu enfeksiyonu nedeniyle solunum sıkıntısı yaşayan ve yüksek akım oksijen tedavisi alan pediatrik hastalarda sürüntü pozitifliği, eşlik eden kronik hastalık ve prematüritenin tedaviye yanıta etkisini araştırmaktır. Gereç ve yöntem: Çalışmaya 1 ay ile 9 yaş arasında solunum sıkıntısı nedeniyle acil servisimize başvuran, alt solunum yolu enfeksiyonu tanısı alan ve yüksek akımlı nazal kanül oksijen tedavisi uygulanan çocuk hastalar dahil edildi. Hasta kayıtları geriye dönük olarak incelendi. Hastaların demografik verileri gözden geçirildi. Hastalar nazofarengeal sürüntü pozitifliğine göre pozitif ve negatif olanlar olarak gruplandırıldı. Solunum sıkıntısına neden olan hastalıklar ve enfeksiyon etkeninin, eşlik eden kronik hastalık varlığının ve erken doğum öyküsünün tedaviye yanıta etkisi araştırıldı. Bulgular: Nazofarengeal sürüntü pozitifliğinin, yüksek akımlı nazal kanül oksijen tedavisi uygulama süresi üzerinde önemli bir etkiye sahip olduğu, ancak ventilatöre bağlanma ihtiyacını ortadan kaldırmada etkisiz olduğu bulundu. Kronik hastalık varlığında tedaviye yanıtın anlamlı oranda azaldığı tespit edildi. Sonuç: Eşlik eden kronik hastalık varlığı, tedaviye cevapsızlıkta etkili en önemli faktör olarak bulundu. Kronik hastalığı olanlarda invaziv solunum destek cihazı uygulamasına hazırlıklı olunmalıdır.

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Cite This Article

KIRLI, U., TOPAL, H., TOPAL, Y., TİRYAKİ, S., KAYILIOĞLU, H., OLGUN, H. (2020). The Effect of Nasopharyngeal Swab Positivity and Accompanying Chronic Disease on High Flow Nasal Cannula Oxygen Therapy. Ege Klinikleri Tıp Dergisi, Cilt: 58 - Sayı: 3, 349–355. https://ajindex.com/articles/219267

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