SavedAdd your journal

Journals / Düşünen Adam - Psikiyatri ve Nörolojik Bilimler Dergisi / 2011 / Cilt: 24 - Sayı: 4

A case of a suicide attempt with sitalopram causing supression of sinusal rhythm with development of atrial rhythm

Sitalopram ile suisid girişimi sonrasında sinüs ritminin baskılanarak atrial ritmin geliştiği bir olgu

SEVDA KORKMAZ
Hasan KORKMAZ
Murad ATMACA
Murat KULOĞLU
Pages
349–351
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In our article, we present a case who developed electrocardiographic changes due to use of citalopram in high doses.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Selective serotonine reuptake inhibitors (SSRI) are known as effective and quite safe antidepressant drugs which inhibit seratonin reuptake in the presynaptic area without affecting the noradrenaline and dopamine reuptake.
📊
Key Findings & Data:Nevertheless, in high dose use of all antidepressants, including SSRI, some toxic effects might be observed in central nervous system, respiratory system and cardiovascular system.
💡
Conclusion & Impact:In our article, we present a case who developed electrocardiographic changes due to use of citalopram in high doses.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Selective serotonine reuptake inhibitors (SSRI) are known as effective and quite safe antidepressant drugs which inhibit seratonin reuptake in the presynaptic area without affecting the noradrenaline and dopamine reuptake. Nevertheless, in high dose use of all antidepressants, including SSRI, some toxic effects might be observed in central nervous system, respiratory system and cardiovascular system. In our article, we present a case who developed electrocardiographic changes due to use of citalopram in high doses.

Özet

Selektif serotonin geri alım inhibitörleri (SSRI), norepinefrin veya dopamin geri alımını etkilemeden, presinaptik alanda serotonin geri alımını inhibe eden, etkili ve oldukça güvenli olarak bilinen antidepresan ilaçlardır. Bununla beraber, SSRI’lar da dahil, tüm antidepresan ilaçların yüksek dozda kullanımlarına bağlı olarak merkezi sinir sistemi, solunum sistemi ve kardiyovasküler sistemde birtakım toksik etkiler gözlenebilmektedir. Yazımızda, bir SSRI olan sitalopramın yüksek dozlarda alınmasıyla EKG’de bazı değişiklikler gözlemlediğimiz bir olgu sunulacaktır.

🔖

Cite This Article

KORKMAZ, S., KORKMAZ, H., ATMACA, M., KULOĞLU, M. (2011). A case of a suicide attempt with sitalopram causing supression of sinusal rhythm with development of atrial rhythm. Düşünen Adam - Psikiyatri ve Nörolojik Bilimler Dergisi, Cilt: 24 - Sayı: 4, 349–351. https://ajindex.com/articles/218618

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (11)

  1. Mills KC. Tricyclic Antidepressants: In Tintinalli JE, Kelen GD, Stapczynski JS (editors). Emergency Medicine: A Comprehensive Study Guide. Fifth ed. New York: McGraw-Hill, 2000, 1063- 1072
  2. Stork CM. Serotonin Reuptake Inhibitors and Atypical Antidepressants: In Goldfrank LR, Flomenbaum NE, Lewin NA, Howland MA, Hoffman RS (editors). Goldfrank’s Toxicologic Emergencies. Seventh ed. New York: McGraw- Hill, 2002, 865- 874
  3. Taylor D. Antidepressant drugs and cardiovascular pathology: A clinical overview of effectiveness and safety. Acta Psychiatr Scand 2008; 118:434-442
  4. Bezchlibnyk-Butler K, Aleksic I, Kennedy SH. Citalopram: a review of pharmacological and clinical effects. Psychiatry Neurosci 2000; 25:241–254
  5. Potter WZ, Hollister LE. Antidepressant Agents: In Katzung BG (editor). Basic and Clinical Pharmacology. A LANGE medical book. New York: McGraw-Hill, 2004, 482-496
  6. Walter FG, Gogarty S, Callaham M. Antidepressants and monoamine oxidase inhibitors: In Rosen P, Barkin R (editors). Emergency Medicine Concepts and Clinical Practice. Fourth ed. St Louis (MO): Mosby-Year Book, 1998, 1325-1342
  7. Sarko J. Antidepressants, old and new. A review of their adverse effects and toxicity in overdose. Emerg Med Clin North Am 2000; 18:637-654
  8. Stoner SC, Marken PA, Watson WA, Switzer JL, Barber MF, Meyer VL, Sommi RW Jr, Steele MT. Antidepressant overdoses and resultant emergency department services: The impact of SSRI. Psychopharmacol Bull 1997; 33:667-670
  9. Pacher P, Ungvari Z, Nanasi PP, Furst S, Kecskemeti V. Speculations on difference between tricyclic and selective serotonin reuptake inhibitor antidepressants on their cardiac effects. Is there any? Curr Med Chem 1999; 6:469-480
  10. Personne M, Sjoberg G, Personne H. Citalopram overdose: review of cases treated in Swedish Hospitals. J Toxicol Clin Toxicol 1997; 35:237-240
  11. Enemark B. The importance of ECG monitoring in antidepressant treatment. Nord J Psychiatry 1997; 47:57-65.