Journals / Düşünen Adam - Psikiyatri ve Nörolojik Bilimler Dergisi / 2010 / Cilt: 23 - Sayı: 1

Comorbidity of anxiety disorders in schizophrenia: Relationship with sociodemographic and clinical variables

Şizofrenide anksiyete bozuklukları eştanısı: Sosyodemografik ve klinik özellikler ile ilişkisi

Pages
18–24
DOI
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Conclusion: These results emphasize the importance of screening for comorbid anxiety disorders in the prognosis and treatment of schizophrenia and display the need for new contemporary treatment modalities.

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Objective & Hypothesis:Objective: In this study, we aimed to investigate the frequency of comorbidity of anxiety disorders and schizophrenia and to assess its relation with sociodemographic and clinical variables Methods: One hundered five patients diagnosed as having schizophrenia according to DSM-IV were recruited from Bakırköy Research and Training Hospital for Psychiatry, Neurology and Neurosurgery, Treatment Education and Research Center for Psychotic Disorders.
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Key Findings & Data:The collected data has been evaluated by using SPSS 10.0.
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Conclusion & Impact:Conclusion: These results emphasize the importance of screening for comorbid anxiety disorders in the prognosis and treatment of schizophrenia and display the need for new contemporary treatment modalities.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: In this study, we aimed to investigate the frequency of comorbidity of anxiety disorders and schizophrenia and to assess its relation with sociodemographic and clinical variables Methods: One hundered five patients diagnosed as having schizophrenia according to DSM-IV were recruited from Bakırköy Research and Training Hospital for Psychiatry, Neurology and Neurosurgery, Treatment Education and Research Center for Psychotic Disorders. The data from the participants were collected using sociodemographic data form, Structured Clinical Interview for the Diagnostic and Statistical Manual of Mental Disorders - Fourth Edition, Positive and Negative Syndrome Scale (PANSS), Hamilton Anxiety Rating Scale (HAM-A), Barnes Akathisia Rating Scale (BARS). The collected data has been evaluated by using SPSS 10.0. Results: Among the participants, 23,80% (n=25) had no anxiety disorders whereas 47,61% (n=50) had diagnosis for more than one anxiety disorder; 4,76% (n= 5) had panic disorder, 0,95% (n=1) had obsessive-compulsive disorder, 0,95% (n=1) had agorophobia, 4,76% (n=5) had social anxiety disorder, 14,28% (n=15) had special phobia, and 2,85% (n=3) had anxiety disorder otherwise unspecified as comorbid diagnosis along with schizophrenia. Anxiety symptoms were more frequent in patients with a story of childhood separation anxiety, school phobia and childhood maltreatment. Conclusion: These results emphasize the importance of screening for comorbid anxiety disorders in the prognosis and treatment of schizophrenia and display the need for new contemporary treatment modalities.

Özet

Amaç: Bu araştırmada, şizofreni tanılı hastalarda anksiyete bozukluğu eştanısının araştırılması, anksiyete bozukluğu olan ve olmayan şizofreni hastalarının sosyodemografik özellikler ve klinik özellikler açısından karşılaştırılması amaçlanmaktadır. Yöntem: Bakırköy Prof. Dr. Mazhar Osman Ruh Sağlığı ve Sinir Hastalıkları Eğitim ve Araştırma Hastanesi Psikotik Bozukluklar Tedavi Eğitim ve Araştırma Merkezi tarafından takip edilen, DSM-IV TR’ye göre şizofreni tanılı 105 hasta bu çalışmaya dahil edilmiştir. Katılımcılara sosyodemografik veri formu, DSM-IV Eksen I Bozuklukları İçin Yapılandırılmış Klinik Görüşme Ölçeği (SCID-I), Pozitif ve Negatif Sendrom Ölçegi (PANSS), Hamilton Anksiyete Değerlendirme Ölçeği (HAM-A) ve Barnes Akatizi Ölçeği (BAÖ) görüşmeci tarafından uygulanmıştır. Bulgular: Olguların %23,80’inde (n=25) herhangi bir anksiyete bozukluğu saptanmazken, %47,61’inde (n=50) birden fazla anksiyete bozukluğu, %4,76’sında (n=5) panik bozukluğu, %0,95’inde (n=1) obsesif kompulsif bozukluk, %0,95’inde (n=1) agarofobi, %4,76’sında (n=5) sosyal anksiyete bozukluğu, %14,28’inde (n=15) özgül fobi ve %2,85’inde (n=3) başka türlü adlandırılamayan anksiyete bozukluğu bulunmuştur. Anksiyete bozukluğu olan ve olmayan olgular arasında cinsiyet, yaş, aile öyküsü, şizofreni alt tipi, alkol ve madde kullanım öyküsü ve kendine zarar verici davranış, patolojik ebeveynin varlığı, bir ebeveynin yokluğu, PANSS-pozitif, PANSS-negatif, PANSS-genel ve PANSS-total puanları açısından istatistiksel olarak anlamlı farklılık saptanmamıştır. Okul fobisi veya başka bir fobinin varlığı ve çocuklukta kötü muamele öyküsü anksiyete bozukluğu olan olgularda, anksiyete bozukluğu olmayan olgulara göre anlamlı derecede daha fazla bulunmuştur. Sonuç: Bu sonuçlar şizofrenide anksiyete bozukluğu eştanısının önemini vurgulamakta, tedavi yaklaşımlarında yeni arayışları gündeme getirmektedir.

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Cite This Article

BELENE, E., BELENE, A., ALGIN, F., SAMANCI, A., ERKMEN, H. (2010). Comorbidity of anxiety disorders in schizophrenia: Relationship with sociodemographic and clinical variables. Düşünen Adam - Psikiyatri ve Nörolojik Bilimler Dergisi, Cilt: 23 - Sayı: 1, 18–24. https://ajindex.com/articles/218602

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