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Journals / Çocuk Enfeksiyon Dergisi / 2009 / Cilt: 3 - Sayı: 2

Development of intestinal flora in infancy and ıts effects on immune system

Bebeklikte barsak florası gelişimi ve immun sisteme etkiler

NİLGÜN KÜLTÜRSAY
Pages
75–78
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Probiotics, prebiotics,and synbiotics may be helpful in reducing severe infectious complications such as necrotising enterocolitis in preterm infants and preventing allergic disorders in infants with a high risk of atopy due to their positive effects on the development of intestinal microflora.

📌 3 Key Takeaways

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Objective & Hypothesis:Intestinal immune system, in which intestinal flora play an important role, can be programmed to be more efficient against infections as well as producing less allergic and autoimmune disorders.
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Key Findings & Data:Beginning with the diet in pregnancy, then by vaginal delivery and human milk -with its synbiotic effect - maturation of healthy gastrointestinal flora in infants can be supported.
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Conclusion & Impact:Probiotics, prebiotics,and synbiotics may be helpful in reducing severe infectious complications such as necrotising enterocolitis in preterm infants and preventing allergic disorders in infants with a high risk of atopy due to their positive effects on the development of intestinal microflora.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Intestinal immune system, in which intestinal flora play an important role, can be programmed to be more efficient against infections as well as producing less allergic and autoimmune disorders. Beginning with the diet in pregnancy, then by vaginal delivery and human milk -with its synbiotic effect - maturation of healthy gastrointestinal flora in infants can be supported. Probiotics, prebiotics,and synbiotics may be helpful in reducing severe infectious complications such as necrotising enterocolitis in preterm infants and preventing allergic disorders in infants with a high risk of atopy due to their positive effects on the development of intestinal microflora.

Özet

Barsak florasının çok önemli bir kısmını oluşturduğu intestinal immun sistem yaşamın erken dönemlerinden itibaren infeksiyonlarla daha iyi mücadele ederken daha az allerji ve otoimmunite geliştirmek üzere programlanabilir. Gebelikteki diyetten başlayarak vajinal doğum şekli ve sinbiyotik özellikleri olan anne sütünün verilmesinin gastrointestinal flora gelişimine olumlu etkileri vardır. Bu floranın gelişimini destekleyecek pro-pre-sinbiyotiklerin kullanımı prematüre bebeklerde ağır infeksiyöz komplikasyonların ve özellikle nekrotizan enterokolitin azaltılmasında ve yüksek atopi riskli bebeklerde allerjinin gelişmesini engellemekte yararları olabilir

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Cite This Article

KÜLTÜRSAY, N. (2009). Development of intestinal flora in infancy and ıts effects on immune system. Çocuk Enfeksiyon Dergisi, Cilt: 3 - Sayı: 2, 75–78. https://ajindex.com/articles/218353

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References (15)

  1. Saevedra JM. Nutrition in clinical practice 2007; 22: 351-65
  2. Tezcan Fİ. İntestinal immun sistem. Türkiye Klinikleri J Pediatr Sci 2007; 3(6): 65-7
  3. Caicedo RA, Schanler RJ, Li N, Neu J. The developing intestinal ecosystem: Implications for the neonate. Pediatr Res 2005; 58: 625-8
  4. Neish A. Microbes in gastrointestinal health and disease Gastroenterology 2009; 136: 65-80
  5. Hammerman C, Kaplan M. Probiotics and neonatal intestinal infection Current Opinion in Infectious Diseases 2006; 19: 277–82
  6. Newburg DS, Walker WA. Protection of the Neonate by the Innate Immune System of Developing Gut and of Human Milk. Pediatr Res 2007; 61: 2–8
  7. Huurre A, Laitinen K, Rautava S, Korkeamäki M, Isolauri E. Impact of maternal atopy and probiotic supplementation during pregnancy on infant sensitization: a double-blind placebo-controlled study. Clin Exp Allergy 2008; 38(8): 1342-8
  8. Hakansson S Kallen K. Caesarian section increases the risk of hospital care in childhood for asthma and gastroenteritis Clin Exp Allergy 2003; 33: 757-64 9. Swanson D. Indigenous Flora. In: Feigin RD, Cherry JD(eds)Textbook of Pediatric Infectious Diseases. 5th ed. Philadelphia: WB Saunders 2004.p.107-14
  9. Harmsen, HJM., Wildeboer-Veloo, ACM., Raangs GC et al. Analysis of intestinal flora development in breast-fed and formula-fed infants by using molecular identification and detection methods. J Ped Gastroenterol Nutr 2000; 30: 61-7
  10. Gueimonde M, Laitinen K, Salminen S, Isolauri E. Breast milk: a source of bifidobacteria for infant gut development and maturation? Neonatology 2007; 92: 64–6
  11. Grönlund MM, Gueimonde M,Laitinen K et al. Maternal breast-milk and intestinal bifidobacteria guide the compositional development of the Bifidobacterium microbiota in infants at risk of allergic disease. Clin Exp Allergy 2007; 37: 12.p1764-72
  12. Sakata H, Yoshioka H, Fujita K. Development of the intestinal flora in very low birthweight infants compared to normal full-term newborns. Eur J Ped 1985; 114: 186-90
  13. Teitelbaum JE, Walker WA. Nutritional impact of pre-and probiotics as protective gastrointestinal organisms. Ann Rev Nut 2002; 22: 107-38
  14. Bjorksten B, Naaber P, Sepp E, Mikelsaar M. Allergy development and the intestinal microflora during the first year of life. J Allergy Clin Immunol 2001; 108: 516-20
  15. Rinne M, Kalliomaki M, Salminen S, Isolauri E. Probiotic intervention in the first months of life: short-term effects on gastrointestinal symptoms and l