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Journals / Turkish Journal of Medical Sciences / 2014 / Cilt: 44 - Sayı: 6

Investigation of linezolid resistance in Staphylococcus epidermidis: first reported linezolid resistant coagulase negative staphylococcus in Turkey

Barış YALÇIN
Mehmet Burak SELEK
Bayhan BEKTÖRE
Tuğrul HOŞBUL
Mustafa ÖZYURT
Pages
1136–1138
Publication Date
2014-06-01
DOI
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⚡ TL;DR(Too Long; Didn't Read)

The A-site and P-site of large ribosomal units are among these interaction regions (17).Nucleotide A2309 is located in

📌 3 Key Takeaways

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Objective & Hypothesis:It is thought that linezolid binds to any location in the vicinity of the peptidyl transferase center (PTC) (4).
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Key Findings & Data:The PTC is located in domain V of 23S rRNA, and this center plays a key role in peptide bond formation and peptide release (16).
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Conclusion & Impact:The A-site and P-site of large ribosomal units are among these interaction regions (17).Nucleotide A2309 is located in
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Turk J Med Sci 2014 · 44(6): 1136-1138. Full text: pdf Other articles published in the same issue: Turk J Med Sci · vol.44

Abstract

position 2309. It is thought that linezolid binds to any location in the vicinity of the peptidyl transferase center (PTC) (4). The PTC is located in domain V of 23S rRNA, and this center plays a key role in peptide bond formation and peptide release (16). Although PTC is known as the primer binding site of the drug, it is controversial that different sites of ribosome can interact with linezolid. The A-site and P-site of large ribosomal units are among these interaction regions (17).Nucleotide A2309 is located in

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Cite This Article

YALÇIN, B., SELEK, M. B., BEKTÖRE, B., HOŞBUL, T., ÖZYURT, M. (2014). Investigation of linezolid resistance in Staphylococcus epidermidis: first reported linezolid resistant coagulase negative staphylococcus in Turkey. Turkish Journal of Medical Sciences, Cilt: 44 - Sayı: 6, 1136–1138. https://ajindex.com/articles/218247

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