AI Summary & Key Takeaways
AI InsightEfforts should be made to reduce the risk factors mentioned.
📌 3 Key Takeaways
Özet
Introduction: To investigate Intracranial Hemorrhage Incidence (ICH) and Risk Factors in Very Low Birth Weight Preterm Newborns. Methods: Data of 816 preterm newborns with birth weight (BW) <1500 g [24-32 weeks of gestation (GW)] followed in our unit over a four-year period (2011-2014) were retrospectively analyzed in terms of ICH and risk factors. The data of the new- borns with and without ICH were compared with Student T and Chi-square tests. Independent risk factors that are effective on ICH were determined by logistic regression analysis. Results: Average gestational week and birth weight of 232 patients with ICH were 27.6±2.2 weeks and 945±241 g, respec- tively and the incidence of ICH was found 28.4% (grade I, II, III and IV ICH rates; 12.4%, 6.6%, 6% and 3.4%, respectively). In single variable comparison, GW (p<0.001), BW (p<0.001), vaginal birth (p=0.014), resuscitation (p<0.001), respiratory distress syndrome (RDS) (p<0.001), mechanical ventilation (MV) (p<0.001), high frequency oscillatory ventilation (HFOV) (p<0.001), nasal intermittent positive pressure (NIPPV) (p<0.001), patent ductus arteriosus (PDA) (p<0.001), sepsis (p<0.001), erythro- cyte transfusion (p<0.001), pneumothorax (p= 0.017) and inotrope use (p<0.001) were found statistically significant. In lo- gistic regression analysis, resuscitation [relative risk (RR): 1.85, confidence interval (Cİ): 1.13-3.04], PDA (RR: 1.74, Cİ: 1.19-2.53), erythrocyte transfusion (RR: 1.87, Cİ: 1.24-2.82), MV (RR: 2.19, Cİ: 1.24-3.88), HFOV (RR: 1.61, Cİ: 1-2.59) and NIPPV (RR: 1.61, Cİ: 1.13-2.32) were detected as significant independent risk factors. Discussion and Conclusion: Despite the advancing technology, the desired reduction in the ICH frequency could not be achieved due to the increase in the survival numbers of immature newborns. Efforts should be made to reduce the risk factors mentioned.