Journals / Haseki Tıp Bülteni / 2015 / Cilt: 53 - Sayı: 1

The Effects of Thoracic Epidural Analgesia on Postoperative Pain and Myocardial Protection in Coronary Artery Bypass Surgery

Koroner Arter Cerrahisinde Torakal Epidural Analjezinin Postoperatif Ağrı ve Miyokard Korunması Üzerine Etkileri

Pages
72–76
DOI
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Conclusion: TEA with levobupivakain in CABG was found to provide stable hemodynamics, effective analgesia and to shorten length of hospital stay.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: Thoracic epidural analgesia (TEA) in cardiac surgery provides stable hemodynamics and postoperative analgesia by reducing stress response.
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Key Findings & Data:The aim of this study was to investigate the effects of TEA in coronary artery bypass grafting (CABG) on postoperative pain, myocardial protection, intensive care unit (ICU) and hospital length of stay.Methods: After receiving approval from the hospital scientific committee and obtaining written informed consent from the participants, 40 patients, who were undergoing elective CABG, were included in the study.
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Conclusion & Impact:Conclusion: TEA with levobupivakain in CABG was found to provide stable hemodynamics, effective analgesia and to shorten length of hospital stay.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: Thoracic epidural analgesia (TEA) in cardiac surgery provides stable hemodynamics and postoperative analgesia by reducing stress response. The aim of this study was to investigate the effects of TEA in coronary artery bypass grafting (CABG) on postoperative pain, myocardial protection, intensive care unit (ICU) and hospital length of stay.Methods: After receiving approval from the hospital scientific committee and obtaining written informed consent from the participants, 40 patients, who were undergoing elective CABG, were included in the study. The patients were prospectively randomized into two groups as TEA group (n=20) and control group (n=20). Epidural catheters were placed one day before surgery at the T5-T6 level, levobupivacaine 2 &#956;g/mL and fentanyl 5 mL/hr infusions were initiated in the ICU. Control group received intravenous infusion of fentanyl 8 &#956;g/kg/hr. Infusions continued for 24 hours in both groups. Results: Time to extubation was shorter, postoperative hypertension was less frequent and pain scores were lower in TEA group than in control group (p<0.01). There was no difference in length of stay in the ICU, CK-MB and troponin I levels between the groups, however, length of hospital stay was shorter in TEA group. Conclusion: TEA with levobupivakain in CABG was found to provide stable hemodynamics, effective analgesia and to shorten length of hospital stay.

Özet

Amaç:Kalp cerrahisinde torakal epidural analjezi (TEA) tekniği, postoperatif analjezi ve stres yanıtı azaltarak dengeli bir hemodinami sağlamaktadır. Çalışmamızın amacı, koroner arter baypas cerrahisinde TEA’nın postoperatif ağrı, miyokard korunması, yoğun bakım ve hastanede kalış süresi üzerine etkilerini araştırmaktır. Yöntemler:Hastane bilimsel komite onayı ve onamları alındıktan sonra elektif koroner arter baypas cerrahisi geçirecek 40 hasta çalışmaya alındı. Prospektif planlanan çalışmada hastalar randomize olarak TEA (n=20) ve kontrol grubu (n=20) olarak iki gruba ayrıldı. Epidural kateter hastalara operasyondan bir gün önce T5-T6 seviyesinden yerleştirilerek yoğun bakımda levobupivakain 2 μg/mL ve fentanil 5 mL/saat infüzyonu başlandı. Kontrol grubuna İV fentanil infüzyonu (8 μg/kg/saat) verildi. İnfüzyonlar 24 saat süreyle devam edildi. Bulgular:TEA grubunda ekstübasyon süresi daha kısa, postoperatif hipertansiyon sıklığı daha az ve ağrı skorları kontrol grubuna göre daha düşük bulundu (p<0,01). Yoğun bakımda kalış süresi, CK-MB ve troponin I değerleri iki grup arasında farklı değildi, ancak hastanede kalış süresi TEA grubunda daha kısa kaydedildi. Sonuç: Koroner arter baypas cerrahisinde TEA yöntemi ile levobupivakainin dengeli bir hemodinami, etkili analjezi sağladığı, hastanede kalış sürelerini kısaltığı görüldü.

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Cite This Article

ÇELİK, B. B., KUDSİOĞLU, T., ALICIKUŞ, Z., YAPICI, N., ORHAN, G., TANDOĞAR, N., KAYACIOĞLU, İ., AYKAÇ, Z. (2015). The Effects of Thoracic Epidural Analgesia on Postoperative Pain and Myocardial Protection in Coronary Artery Bypass Surgery. Haseki Tıp Bülteni, Cilt: 53 - Sayı: 1, 72–76. https://ajindex.com/articles/218182

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