Journals / Haseki Tıp Bülteni / 2015 / Cilt: 53 - Sayı: 1

Pulmonary Nocardiosis Induced by Long-Term Use of Steroids on a Bronchiectasis Backgroung

Bronşektazi Zemininde Uzun Süreli Steroid Kullanımına Bağlı Pulmoner Nokardiyoz

Pages
88–91
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In conclusion, considering the high frequency of bronchiectasis in our country, the fact that nocardia may develop due to inappropriate long-term steroid use during an attack should be kept in mind.

📌 3 Key Takeaways

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Objective & Hypothesis:A 45-year-old male was assessed with the complaints of cough, sputum, fever, shortness of breath, tingling and burning in both legs.
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Key Findings & Data:According to the antibiogram results, he was treated with doxycycline, trimethoprim and sulfamethoxazole for 6 months.
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Conclusion & Impact:In conclusion, considering the high frequency of bronchiectasis in our country, the fact that nocardia may develop due to inappropriate long-term steroid use during an attack should be kept in mind.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

A 45-year-old male was assessed with the complaints of cough, sputum, fever, shortness of breath, tingling and burning in both legs. In his history, he had frequent hospitalizations and steroid use. Respiratory system examination revealed inspiratory and expiratory crackles on bilateral lower-middle zones and expiration rhoncus. Laboratory examination revealed leukocytosis and elevated CRP levels; serology for HIV was reported negative. Computed tomography showed diffuse interstitial pneumonia. Electromyography (EMG) showed lower extremity muscle activation compatible with myopathy. Acid-fast bacilli was negative (three consecutive negative microscopy results) and no reproduction was detected in the culture. Nocardia spp. growth was detected in sputum culture. According to the antibiogram results, he was treated with doxycycline, trimethoprim and sulfamethoxazole for 6 months. At the end of treatment, the lesions were found to be regressed on computed tomography. In conclusion, considering the high frequency of bronchiectasis in our country, the fact that nocardia may develop due to inappropriate long-term steroid use during an attack should be kept in mind.

Özet

Kırk beş yaşında erkek, öksürük, balgam, ateş, nefes darlığı, her iki bacakta karıncalanma ve yanma şikayeti ile değerlendirildi. Özgeçmişinde; bronşektazi nedeni ile sık sık hastaneye yatış ve steroid kullanımı vardı. Solunum sistemi muayenesinde bilateral orta alt zonlarda inspiratuvar ve ekspiratuvar raller ile ekspiryumda ronküsü mevcuttu. Laboratuvar incelemesinde lökositoz ve CRP yüksekliği mevcuttu. Serolojide HIV negatif olarak saptandı. Hastanın bilgisayarlı toraks tomografisinde diffüz interstisyel pnömonisi mevcuttu. Elektromiyografi grafisinde (EMG) alt ekstremite kaslarında miyopati ile uyumlu aktive saptandı. Aside rezistan basil 3 kez negatif olup kültürlerinde üreme saptanmadı. Balgam kültüründe Nocardia spp. üremesi saptandı. Antibiyogram sonucuna göre 6 ay trimetoprim sulfametaksazol ve doksisiklin ile tedavi edildi. Tedavinin bitiminde çekilen toraks tomografisinde tanımlanan lezyonların regrese olduğu saptandı. Sonuç olarak ülkemizde bronşektazi hastalarının çok olması ve atak sırasında sık sık uygunsuz ve uzun süreli steroid kullanılması nedeni ile nokardiya enfeksiyonunun da gelişebileceği akılda tutulmasını gerektirmektedir.

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Cite This Article

ÖZDEMİR, L., ÖZDEMİR, B., TEMELLİ, M., HATİPOĞLU, O. N. (2015). Pulmonary Nocardiosis Induced by Long-Term Use of Steroids on a Bronchiectasis Backgroung. Haseki Tıp Bülteni, Cilt: 53 - Sayı: 1, 88–91. https://ajindex.com/articles/218179

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