Synthesis of n-Alkylnaphthalenes via Semicarbazones

Key Findings & Data:The semicarbazones were reduced by modified Wolff-Kishner reductions to give 1-n-alkylnaphthalenes in excellent yields as manageable yellow or orange viscous oils.

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Conclusion & Impact:This study offers an excellent preparative method for the synthesis of 1-n-alkylnaphthalenes from semicarbazones, via a 3-step procedure.

🔬Design:Research Article

📍Scope:Comprehensive Sample

⚙️Variables:Alkylnaphthalenes · Semicarbazones · Wolff-Kishner reductions

Abstract

A number of 1-n-alkylnaphthalenes were prepared via the respective semicarbazones. The semicarbazones were reduced by modified Wolff-Kishner reductions to give 1-n-alkylnaphthalenes in excellent yields as manageable yellow or orange viscous oils. The semicarbazones were prepared from ketones, which are the addition products of Grignard reagents to nitriles. This study offers an excellent preparative method for the synthesis of 1-n-alkylnaphthalenes from semicarbazones, via a 3-step procedure.

Özet

A number of 1-n-alkylnaphthalenes were prepared via the respective semicarbazones. The semicarbazones were reduced by modified Wolff-Kishner reductions to give 1-n-alkylnaphthalenes in excellent yields as manageable yellow or orange viscous oils. The semicarbazones were prepared from ketones, which are the addition products of Grignard reagents to nitriles. This study offers an excellent preparative method for the synthesis of 1-n-alkylnaphthalenes from semicarbazones, via a 3-step procedure.

Keywords

Alkylnaphthalenes Semicarbazones Wolff-Kishner reductions Alkyl-1-naphthyl ketones Grignard reaction

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Cite This Article

ZENGİN, G., HUFFMAN, J. W. (2006). Synthesis of n-Alkylnaphthalenes via Semicarbazones. Turkish Journal of Chemistry, Cilt: 30 - Sayı: 2, 139–144. https://ajindex.com/articles/218013

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