Journals / Ege Klinikleri Tıp Dergisi / 2020 / Cilt: 58 - Sayı: 3

Causeor Result of Hyperemesis Gravdarum? DEficiency of Vitamin B12 and Folate

Hiperemezis Gravidarumda Sebep Mi Sonuç Mu? Vitamin B12 Ve Folat Eksikliği

Pages
257–262
DOI
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⚡ TL;DR(Too Long; Didn't Read)

Also, there was a significant relation between keton levels and folate.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Hyperemesis gravidarum is a rare condition that is characterised with nosea, vomiting, weigth loss and kenonuria.
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Key Findings & Data:Vitamin B12 and folic acid are crucia lvitamins forc ell development, proliferation, placental and fetaldevelopment.
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Conclusion & Impact:Also, there was a significant relation between keton levels and folate.
🔬Design:Research Article
📍Scope:2017 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: Hyperemesis gravidarum is a rare condition that is characterised with nosea, vomiting, weigth loss and kenonuria. Vitamin B12 and folic acid are crucia lvitamins forc ell development, proliferation, placental and fetaldevelopment. Deficiency of these vitamins leads to various pregnancy complications. Aim of our study is to reveal the relationship between hyperemesis gravidarumand vitamin B12 and folate regarding the effect of them on placental development. Methods: We included our study 157 pregnants that had hyperemesis gravidarumand 242 healty pregnants that had similar characteristics with study group who applied to Samsun Obstetrics and Gynecology Hospital and Health Sciences University Samsun Educational and Research Hospital Obstetrics and Gynecology Department in between January 2017 and July 2018. Folate and vitamin B12 levels of these pregnants were evaluated restrospectively. Results: According to our findings, vitamin B12 levels of hyperemesis cases were found to be lower(p=0.001; p 0.05).According to dual comparison results; folate levels of keton(+) and keton(++) cases was found to be higher than keton (+++) cases (respectively p=0.029; p=0.049; p 0.05). Conclusion: According to our study results we found significant correlation between hypremesis gravidarum and vitamin B12 levels. Also, there was a significant relation between keton levels and folate.

Özet

Amaç: Hiperemezis gravidarum nadir görülen bulantı, kusma, kilo kaybı ve ketonüri ile karakterize bir durumdur. Vitamin B12 ve folik asit hücre büyümesi, çoğalması, plasenta ve fetal gelişim için çok önemli vitaminlerdir. Eksikliklerinde çeşitli gebelik komplikasyonlarına yol açar. Çalışmamızın amacı vitamin B12 ve folatın plasental gelişim üzerindeki etkilerinden yola çıkarak hiperemezis ile ilişkisini ortaya koymaktır. Gereç ve Yöntem: Çalışmamıza 2017 Ocak -2018 Temmuz ayları arasında Samsun Kadın Hastalıkları ve Doğum Hastanesi ve Sağlık Bilimleri Üniversitesi Samsun Eğitim ve Araştırma Hastanesi Kadın Hastalıkları ve Doğum Bölümü’ne başvuran hiperemezis gravidarum olan 157 ve vaka grubuyla benzer özelliklere sahip sağlıklı 242 gebe dahil edildi. Bu gebelerin folat ve vitamin B12 düzeyleri retrospektif olarak değerlendirildi. Bulgular: Çalışmamızın sonuçlarına göre hiperemezis gravidarum görülen olguların vitamin B12 vitamini ölçümleri daha düşüktür(p=0.001; p 0.05). Yapılan ikili karşılaştırma sonuçlarına göre; keton düzeyi pozitif (+) ve pozitif (++) olan olguların folat ölçümleri, keton düzeyi pozitif (+++) olan olgulardan daha yüksektir (sırasıyla p=0.029; p=0.049; p 0.05). Sonuç: Çalışmamızın sonuçlarına göre hiperemezis gravidarum ve vitamin B12 arasında anlamlı bir ilişki saptadık. Ayrıca keton düzeyleri ile folat seviyesi de ilişkili idi.

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Cite This Article

GÜVEY, H., ÇELIK, S., ÇALIŞKAN, C. S., YAŞAR, B., YAZICIOĞLU, B., TÜRE, E., ULUBAŞOĞLU, H. (2020). Causeor Result of Hyperemesis Gravdarum? DEficiency of Vitamin B12 and Folate. Ege Klinikleri Tıp Dergisi, Cilt: 58 - Sayı: 3, 257–262. https://ajindex.com/articles/217835

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