Journals / Gülhane Tıp Dergisi / 2013 / Cilt: 55 - Sayı: 1

Neonatal alloimmune thrombocythopenia and congenital parauretral cyst co-existance

Neonatal alloimmün trombositopeni ve paraüretral kist birlikteliği

Pages
63–65
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We would like to remind them to the neonatal health personell again; and present the co-existence of NAIT and paraurethral cyst.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Neonatal alloimmune thrombocytopenia (NAIT) is one of the etiological factors of severe neonatal thrombocytopenia; it is caused by feto-maternal incompatibility of “thrombocyte specific alloantigens”.
📊
Key Findings & Data:Paraurethral cysts are rarely seen yellow-orange color cystic mass and found at the bilateral urethral meatus.
💡
Conclusion & Impact:We would like to remind them to the neonatal health personell again; and present the co-existence of NAIT and paraurethral cyst.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Neonatal alloimmune thrombocytopenia (NAIT) is one of the etiological factors of severe neonatal thrombocytopenia; it is caused by feto-maternal incompatibility of “thrombocyte specific alloantigens”. Intracranial hemorrhage is the most severe complication of NAIT and it can be seen in the prenatal period. It is diagnosed by medical history, clinical findings, laboratory studies and ruling out the other reasons of neonatal thrombocytopenia. Paraurethral cysts are rarely seen yellow-orange color cystic mass and found at the bilateral urethral meatus. They are usually not recognized. In the present paper, a newborn baby with indirect hyperbilirubinemia who was diagnosed incidentally as NAIT and paraurethral cyst at the routine clinical and laboratory examination is reported. We would like to remind them to the neonatal health personell again; and present the co-existence of NAIT and paraurethral cyst.

Özet

Yenidoğanda ciddi trombositopeni nedenlerinden biri de “trombosite özgü alloantijenlerin” sonucunda ortaya çıkan neonatal alloimmun trombositopenidir (NAIT). NAIT’nın en önemli komplikasyonu, prenatal dönemde de görülebilen, hayatı tehdit eden intrakraniyal kanamalardır. Tanı aile öyküsü, klinik bulgular, laboratuvar ve neonatal trombositopeni yapabilecek diğer nedenlerin dışlanması ile konur. Paraüretral kistler yenidoğan kızlarda nadir görülen, üretra açılımının her iki tarafında olabilen sarı-portakal renginde kistik kitlelerdir. Tanısı çoğunlukla atlanmaktadır. Burada, sarılık nedeniyle takip edilirken rutin incelemelerinde trombositopeni tespit edilerek NAIT ve paraüretral kist tanısı alan bir vaka, yenidoğan servisinde çalışan hekimlere hem bu konuyu tekrar hatırlatmak, hem de literatürde bahsedilmeyen NAIT ile paraüretral kist birlikteliği ile sunuldu.

🔖

Cite This Article

KIŞLAL, F. M., AKBAŞ, T., GÜVELOĞLU, M. (2013). Neonatal alloimmune thrombocythopenia and congenital parauretral cyst co-existance. Gülhane Tıp Dergisi, Cilt: 55 - Sayı: 1, 63–65. https://ajindex.com/articles/216928

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (12)

  1. Acunaş B. Hemostatik hastalıklar. Yurdakök M, Erdem G ed. Neonatoloji. İkinci baskı, Ankara: Türk Neonatoloji Derneği. 2004; 615
  2. O. Herek, H. Ergin. Paraurethral cysts in nexborn: A case report and review of literature. Eur J Pediatr Surg 2000; 10: 65-67
  3. Spencer JA, Burrows RF. Feto-maternal alloimmune thrombocytopenia: a literature review and statistical analysis. Aust. NZ J. Obstet. Gynaecol 2001; 41: 45-55
  4. Williamson LM, Hackett G, Rennie J et al. The natural history of fetomaternal alloimmunization to the platelet- specific antigen HPA-1a (PlA1, Zwa) as determined by antenatal screening. Blood 1998;92:2280-2287
  5. Kjeldsen-Kragh J, Killie MK, Tomter G et al. A screening and intervention program aimed to reduce mortality and serious morbidity associated with severe neonatal alloimmune thrombocytopenia. Blood 2007; 110: 833- 839
  6. Skogen B, Husebekk A, Killie MK, Kjeldsen-Kragh J. Neonatal alloimmune thrombocytopenia is not what it was. A lesson learned from from a large prospective screening and intervention program. Scand J Immunol 2009; 70: 531-534
  7. Bussel JB, Primiani A. Fetal and neonatal alloimmune thrombocytopenia: progress and ongoing debates. Blood Rev 2008; 22: 33-52
  8. Roberts I, Muray NA. Neonatal thrombocytopenia: causes and management. Arch Dis Child Fetal Neonatal Ed 2003; 88: F359-F364
  9. Rayment R, Brunskill SJ, Soothill PW, Roberts DJ, Bussel JB, Murphy MF. Antenatal interventions for fetomaternal alloimmune thrombocytopenia. Cochrane Database Syst Rev 2011; 11:CD004226
  10. Birchall JE, Murphy MF, Kaplan C, Kroll H. European Fetomaternal Alloimmune Thrombocytopenia Study Group. European collaborative study of the antenatal management of feto-maternal alloimmune thrombocytopenia. Br J Haematol 2003; 122: 275-288
  11. Murphy MF, Williamson LM. Antenatal screening for fetomaternal alloimmune thrombocytopenia: an evaluation using the criteria of the UK national screening committee. Br J Haematol 2000; 111: 726-732
  12. Uhrynowska M, Niznikowska-Marks M, Zupanska B. Neonatal and maternal thrombocytopenia: inci-dence and immune background. Eur J Haematol. 2000; 64: 42-46.