Journals / Journal of Clinical Research in Pediatric Endocrinology / 2016 / Cilt: 8 - Sayı: 1

Evaluation of Periaortic Adiposity and Metabolic Disorders in Obese Children

Pages
74–79
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: The measurement of PAFT in obese children and adolescents may be a good method to reveal the presence of early cardiovascular risk.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: To evaluate the relationship between periaortic fat thickness (PAFT) and parameters involved in the development of metabolic complications of the cardiovascular system in obese children and to assess the usefulness of echocardiographic measurements of PAFT in correlation with cardiovascular risk factors.Methods: The study was conducted with 263 obese and 100 healthy children and adolescents.
📊
Key Findings & Data:PAFT was measured with echocardiography method which was recently performed in obese children and adolescents.Results: PAFT was significantly higher in the obese group (0.258±0.031 mm) than in the control group (0.137±0.032 mm) (p<0.001).
💡
Conclusion & Impact:Conclusion: The measurement of PAFT in obese children and adolescents may be a good method to reveal the presence of early cardiovascular risk.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: To evaluate the relationship between periaortic fat thickness (PAFT) and parameters involved in the development of metabolic complications of the cardiovascular system in obese children and to assess the usefulness of echocardiographic measurements of PAFT in correlation with cardiovascular risk factors.Methods: The study was conducted with 263 obese and 100 healthy children and adolescents. PAFT was measured with echocardiography method which was recently performed in obese children and adolescents.Results: PAFT was significantly higher in the obese group (0.258±0.031 mm) than in the control group (0.137±0.032 mm) (p<0.001). In multivariable regression analysis, body mass index-standard deviation score and total body fat were predictors of PAFT. The area under the receiver operating characteristic curve was 0.989 and was quite significant at p<0.001. PAFT above 0.179 mm was determined as the cut-off value in obese children and adolescents (sensitivity=1, specificity=0.97). Conclusion: The measurement of PAFT in obese children and adolescents may be a good method to reveal the presence of early cardiovascular risk.

🔖

Cite This Article

EKLİOĞLU, B. S., ATABEK, M. E., AKYÜREK, N., ALP, H. (2016). Evaluation of Periaortic Adiposity and Metabolic Disorders in Obese Children. Journal of Clinical Research in Pediatric Endocrinology, Cilt: 8 - Sayı: 1, 74–79. https://ajindex.com/articles/216343

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (5)

  1. Cali AM, Caprio S. Obesity in children and adolescents. J Clin Endocrinol Metab 2008;93(Suppl 1):31-36.
  2. Spiroglou SG, Kostopoulos CG, Varakis JN, Papadaki HH. Adipokines in periaortic and epicardial adipose tissue: differential expression and relation to atherosclerosis. J Atheroscler Thromb 2010;17:115-130. Epub 2010 Feb 10 Herouvi D, Karanasios E, Karayianni C, Karavanaki K. Cardiovascular disease in childhood: the role of obesity. Eur J Pediatr 2013;172:721-732. Epub 2013 Jan 23 Britton KA, Pedley A, Massaro JM, Corsini EM, Murabito JM, Hoffmann U, Fox CS. Prevalence, distribution, and risk factor correlates of high thoracic periaortic fat in the Framingham Heart Study. J Am Heart Assoc 2012;1:e004200. Epub 2012 Dec 19 Thanassoulis G, Massaro JM, Corsini E, Rogers I, Schlett CL, Meigs JB, Hoffmann U, O'Donnell CJ, Fox CS. Periaortic adipose tissue and aortic dimensions in the Framingham Heart Study. J Am Heart Assoc 2012;1:e000885. Epub 2012 Dec 19 Spiroglou SG, Kostopoulos CG, Varakis JN, Papadaki HH. Adipokines in periaortic and epicardial adipose tissue: differential expression and relation to atherosclerosis. J Atheroscler Thromb 2010;17:115-130. Epub 2010 Feb 10 Kuczmarski RJ, Ogden CL, Guo SS, Grummer-Strawn LM, Flegal KM, Mei Z, Wei R, Curtin LR, Roche AF, Johnson CL. 2000 CDC Growth Charts for the United States: methods and development. Vital Health Stat 11 2002;246:1-190.
  3. Hatipoglu N, Ozturk A, Mazicioglu MM, Kurtoglu S, Seyhan S, Lokoglu F. Waist circumference percentiles for 7- to 17-year-old Turkish children and adolescents. Eur J Pediatr 2008;167:383- 389. Epub 2007 May 9 National High Blood Pressure Education Program Working Group on High Blood Pressure in Children and Adolescents. The fourth report on the diagnosis, evaluation, and treatment of high blood pressure in children and adolescents. Pediatrics 2004;114(Suppl 2):555-576.
  4. Conwell LS, Trost SG, Brown WJ, Batch JA. Indexes of insulin resistance and secretion in obese children and adolescents: a validation study. Diabetes Care 2004;27:314-319.
  5. Speiser PW, Rudolf MC, Anhalt H, Camacho-Hubner C, Chiarelli F, Eliakim A, Freemark M, Gruters A, Hershkovitz E, Iughetti L, Krude H, Latzer Y, Lustig RH, Pescovitz OH, Pinhas-Hamiel O, Rogol AD, Shalitin S, Sultan C, Stein D, Vardi P, Werther GA, Zadik Z, Zuckerman-Levin N, Hochberg Z; Obesity Consensus Working Group. Childhood obesity. J Clin Endocrinol Metab 2005;90:1871-1887. Epub 2004 Dec 14 Keskin M, Kurtoglu S, Kendirci M, Atabek ME, Yaz