Journals / Gülhane Tıp Dergisi / 2014 / Cilt: 56 - Sayı: 1

Anti IgE tedavi non-atopik astımlılarda kullanılabilir mi: IgE'nin astımdaki rolü hakkında bir olgunun düşündürdükleri

Can anti IgE treatment be used in non-atopic asthma patients; thoughts of case about the role of IgE in asthma

Pages
42–44
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this case report, we present patient of us whose allergy skin tests and specific IgEs were negative, who was started omalizumab treatment following obtaining weak positivity against Dermatofagoides pteronysinus in intradermal tests repetaed with one year interval and who significantly benefited from treatment.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Although elevated serum IgE isaccepted asa sign ofatopy, high total IgE level may accompany with non-allergic asthma and contribute to pathogenesis and severity of the disease independently from atopy.
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Key Findings & Data:Although elevated serum IgE isaccepted asa sign ofatopy, high total IgE level may accompany with non-allergic asthma and contribute to pathogenesis and severity of the disease independently from atopy.
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Conclusion & Impact:In this case report, we present patient of us whose allergy skin tests and specific IgEs were negative, who was started omalizumab treatment following obtaining weak positivity against Dermatofagoides pteronysinus in intradermal tests repetaed with one year interval and who significantly benefited from treatment.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Although elevated serum IgE isaccepted asa sign ofatopy, high total IgE level may accompany with non-allergic asthma and contribute to pathogenesis and severity of the disease independently from atopy. In this case report, we present patient of us whose allergy skin tests and specific IgEs were negative, who was started omalizumab treatment following obtaining weak positivity against Dermatofagoides pteronysinus in intradermal tests repetaed with one year interval and who significantly benefited from treatment.

Özet

Serum IgE yüksekliği atopi belirtisi olarak kabul edilse de nonalerjik astıma eşlik edebilen yüksek total IgE düzeyi atopiden bağımsız olarak hastalığın patogenezine ve ağırlığına katkı yapabilir. Bu olgu sunumunda alerjik deri testleri ve spesifik IgE'Ieri negatif olan intradermal testlerde Dermatofagoides pteronysinus'a karşı zayıf pozitiflik saptanan ve bir yıl süreli omalizumab tedavisinden belirgin fayda gören olgu sunulmaktadır.

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Cite This Article

SEZER, O., KARTALOĞLU, Z., KARTAL, Ö., GÜNEŞ, A., DEMİRER, E., ÖZTÜRK, S., KUTLU, A. (2014). Anti IgE tedavi non-atopik astımlılarda kullanılabilir mi: IgE'nin astımdaki rolü hakkında bir olgunun düşündürdükleri. Gülhane Tıp Dergisi, Cilt: 56 - Sayı: 1, 42–44. https://ajindex.com/articles/215426

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References (6)

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