Journals / GORM:Gynecology Obstetrics & Reproductive Medicine / 2011 / Cilt: 17 - Sayı: 3

Erken doğum eylemiyle total oksidan seviye total antioksidan kapasite ve oksidatif stres indeksi arasındaki ilişkinin değerlendirilmesi: Prospektif - kontrollü

Association between maternal serum total oxidant status total antioxidant status and preterm labor: A prospective - controlled clinical study

Pages
132–136
DOI
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CONCLUSIONS: Improper balance between TAS and TOS may not be a major issue in the pathogenesis of preterm labor in which infection does not precede. ‘Screening or prediction of preterm labor‘ needs new trials with large populations, particularly concerning enviromental and dietary features of the population.

📌 3 Key Takeaways

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Objective & Hypothesis:OBJECTIVE: To measure the levels of individual antioxidant components of pregnants with preterm labor to evaluate their total antioxidant status (TAS), total oxidant status (TOS) and oxidative stress index (OSI).
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Key Findings & Data:STUDY DESIGN: Prospectively-controlled 31 pregnants with a diagnosis of preterm labor (group Ι) and 32 controls (group ΙΙ) were evaluated for demographic data, general and obstetrical physical examination, obstetrical sonography, and routine laboratory tests.
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Conclusion & Impact:CONCLUSIONS: Improper balance between TAS and TOS may not be a major issue in the pathogenesis of preterm labor in which infection does not precede. ‘Screening or prediction of preterm labor‘ needs new trials with large populations, particularly concerning enviromental and dietary features of the population.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

OBJECTIVE: To measure the levels of individual antioxidant components of pregnants with preterm labor to evaluate their total antioxidant status (TAS), total oxidant status (TOS) and oxidative stress index (OSI). STUDY DESIGN: Prospectively-controlled 31 pregnants with a diagnosis of preterm labor (group Ι) and 32 controls (group ΙΙ) were evaluated for demographic data, general and obstetrical physical examination, obstetrical sonography, and routine laboratory tests. TAS, TOS and OSI levels were also measured. RESULTS: There was no difference in terms of demographic data, ultrasound and routine laboratory parameters, total oxidant levels, total antioxidant capacity and oxidative stress index between the two groups (p=0.621, p=0.706 and p=0.450, respectively). CONCLUSIONS: Improper balance between TAS and TOS may not be a major issue in the pathogenesis of preterm labor in which infection does not precede. ‘Screening or prediction of preterm labor‘ needs new trials with large populations, particularly concerning enviromental and dietary features of the population.

Özet

AMAÇ: Erken doğum eylemi tanısı konulmuş gebeler ve gestasyonel haftası uyumlu kontrollerde total antioksidan kapasitelerini (TAK), total oksidan kapasitelerini (TOK) ve oksidatif stress indeksini (OSI) değerlendirmek. GEREÇ VE YÖNTEM: Erken doğum eylemi tanısı konulan 31 gebe (grup I) ve gebelik haftaları ile uyumlu 32 gebelik kontrol grubu (grup II) çalışma kapsamında yer aldı. Tüm hastalarda demografik bilgiler, genel ve obstetrik muayeneler, obstetrik ultrasonografiler, ve rutin laboratuar testleri uygulandı ve kaydedildi. Venöz kan örneğinden TAK, TOK ve OSI seviyeleri de değerlendirildi. SONUÇLAR: Demografik bilgiler, ultrasonografi ve rutin laboratuvar parametreleri (p>0,05) ile TAK, TOK ve OSİ değerleri yönünden farklılık gözlenmedi (sırasıyla p=0,706, p=0,621, p=0,450). TARTIŞMA: TAK ve TOK arasındaki dengesizlik eğer altta yatan enfeksiyon veya erken membran rüptürü yoksa erken doğum eylemi patogenezinde majör bir rol üstlenmeyebilir. “Er - ken doğum eyleminin taramasında veya erken tanısında“ özellikle çevresel faktörlerin ve beslenme özelliklerinin de dikkate alınıp çalışma popülasyonunun büyüklüğünün genişletildiği yeni çalışmalara ihtiyaç vardır.

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Cite This Article

KALAYCI, H., UĞUR, M. G., ÖZTÜRK, E., BALAT, Ö., EREL, Ö. (2011). Erken doğum eylemiyle total oksidan seviye total antioksidan kapasite ve oksidatif stres indeksi arasındaki ilişkinin değerlendirilmesi: Prospektif - kontrollü. GORM:Gynecology Obstetrics & Reproductive Medicine, Cilt: 17 - Sayı: 3, 132–136. https://ajindex.com/articles/214850

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