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Journals / Fırat Tıp Dergisi / 2013 / Cilt: 18 - Sayı: 3

Sirtuin genes and functions

Sirtuin genleri ve işlevleri

Ali BAYRAM
Mehri İĞCİ
Pages
136–140
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

As a result of recent studies, in order to be able to study the role of SIRT genes on biological systems, which is providing positive results for the treatment of many diseases, it is important to understand the molecular and chemical structure of them.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Many studies have been conducted on the potential role, on several diseases, of 23 Sirtuin (SIRT) family genes known as NAD + dependent class III deacetylase enzymes.
📊
Key Findings & Data:Regarding the published literature, Sirtuins have been thought to play a significant role on the treatment of diabetes type II, obesity, cancer, aging, and several neuro-degenerative diseases.
💡
Conclusion & Impact:As a result of recent studies, in order to be able to study the role of SIRT genes on biological systems, which is providing positive results for the treatment of many diseases, it is important to understand the molecular and chemical structure of them.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Many studies have been conducted on the potential role, on several diseases, of 23 Sirtuin (SIRT) family genes known as NAD + dependent class III deacetylase enzymes. Regarding the published literature, Sirtuins have been thought to play a significant role on the treatment of diabetes type II, obesity, cancer, aging, and several neuro-degenerative diseases. As a result of recent studies, in order to be able to study the role of SIRT genes on biological systems, which is providing positive results for the treatment of many diseases, it is important to understand the molecular and chemical structure of them.

Özet

NAD + bağımlı sınıf III deasetilaz enzimler olarak bilinen Sirtuin (SIRT) ailesi genleri ile ilgili olarak çeşitli hastalıklardaki potansiyel rolü üzerine birçok çalışma yapılmıştır. Yayımlanmış literatüre dayanarak Sirtuinlerin; tip II diyabet, obezite, kanser, yaşlanma ve çeşitli nörodejeneratif hastalık- ların tedavisinde önemli rol oynadığı düşünülmektedir. Son yapılan çalışmalar sonucu birçok sağlık probleminin tedavisine yönelik olumlu sonuçlar veren SIRT genlerinin biyolojik sistemlerdeki rolünü çalışabilmek için moleküler ve kimyasal yapısını anlamak çok önemlidir.

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Cite This Article

BAYRAM, A., İĞCİ, M. (2013). Sirtuin genes and functions. Fırat Tıp Dergisi, Cilt: 18 - Sayı: 3, 136–140. https://ajindex.com/articles/214781

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