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Journals / GORM:Gynecology Obstetrics & Reproductive Medicine / 2012 / Cilt: 18 - Sayı: 3

Analysis of Non-Immune Hyrops Fetalis: Evaluation of 15 Cases

Non - İmmün Hidrops Fetalis Analizi: 15 Olgunun Değerlendirilmesi

Turhan ARAN
Hasan BOZKAYA
Mehmet A. OSMANAĞAOĞLU
Pages
13–15
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Detailed ultrasound examination, fetal karyotyping, investigations for fetal infections and genetic diseases should be performed for all NIHF cases with a multidisciplinary approach.

📌 3 Key Takeaways

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Objective & Hypothesis:OBJECTIVES: To evaluation the ultrasound characteristics, etiological factors and perinatal outcome in hydrops fetalis.
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Key Findings & Data:STUDY DESIGN: A total of 15 hydrops fetalis presented in our perinatology unit, were studied prospectively.
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Conclusion & Impact:Detailed ultrasound examination, fetal karyotyping, investigations for fetal infections and genetic diseases should be performed for all NIHF cases with a multidisciplinary approach.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

OBJECTIVES: To evaluation the ultrasound characteristics, etiological factors and perinatal outcome in hydrops fetalis. STUDY DESIGN: A total of 15 hydrops fetalis presented in our perinatology unit, were studied prospectively. RESULTS: The etiology of non-immune hyrops fetalis (NIHF) consisted, 7% (1/15) of thoracic-lung disease, 7% (1/15) of chromosomal abnormality. In 86% of the cases no definitive etiological factor was determined. Outcomes of 15 NIHF pregnancies were termination of pregnancy in 4 cases, intrauterine and neonatal exitus in 1 and 9 case respectively and 1 healthy baby. The perinatal mortality rate of the present study group was 67%. CONCLUSIONS: Non-immune hydrops of newborn infant is associated with a high mortality rate and requires complex diagnostic and therapeutic procedures. Detailed ultrasound examination, fetal karyotyping, investigations for fetal infections and genetic diseases should be performed for all NIHF cases with a multidisciplinary approach.

Özet

AMAÇ: Hidrops fetalis olan olgularda ultrasonografik karakteristik özellikleri, etyolojik faktörleri ve perinatal sonuçları değerlendirmek GEREÇ VE YÖNTEM: Toplam 15 hidrops fetalis olgusu perinatoloji ünitesinde prospektif olarak değerlendirildi. BULGULAR: Non-immün hidrops fetalis etyolojisinde %7 (1/15) torasik-akciğer hastalık, %7 (1/15) kromozomal hastalık tespit edildi. Vakaların % 86'ısında kesin etyolojik faktör belirlenemedi. Toplam 15 NIHF sonuçlarına bakıldığında 4 gebelik temrine, 1 intrauterin eksitus, 9 neonatal eksitus ve 1 sağlıklı bebek elde edildi. Bu çalışmada perinatal mortalite oranı %67 olarak bulundu. SONUÇ: Yenidoğan non-immün hidropsu yüksek mortalite oranı ile bağlantılı olup, kompleks tanı ve terapötik prosedürler gerektirir. Detaylı ultrasonografik inceleme, fetal karyotipleme, fetal infeksiyonlar ve genetik hastalıklar tüm NIHF olgularında mültidisipliner bir yaklaşımla araştırılmalıdır

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Cite This Article

ARAN, T., BOZKAYA, H., OSMANAĞAOĞLU, M. A. (2012). Analysis of Non-Immune Hyrops Fetalis: Evaluation of 15 Cases. GORM:Gynecology Obstetrics & Reproductive Medicine, Cilt: 18 - Sayı: 3, 13–15. https://ajindex.com/articles/214241

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References (13)

  1. Knisely AS. The pathologist and the hydropic placenta, fetus, or infant. Semin Perinatol 1995;19:525-31
  2. McGillivray BC. Hall JG. Nonimmune hydrops fetalis. Pediatr Rev 1987;9:197-202
  3. Andersen HM. Drew JH. Beischer NA. Hutchison AA, Fortune DW. Non-immune hydrops fetalis: changing contribution to perinatal mortality. Br J Obstet Gynaecol 1983;90:636-9
  4. Holzgreve W. Curry CJ. Golbus MS. Callen PW. Filly RA, Smith JC. Investigation of nonimmune hydrops fetalis. Am J Obstet Gynecol 1984;150:805-12
  5. Wy CA. Sajous CH. Loberiza F. Weiss MG. Outcome of infants with a diagnosis of hydrops fetalis in the 1990s. Am J Perinatol 1999;16:561-7
  6. Harahan D. Murphy JF. O'Brien N. et al. Clinico-pathological findings in non-immune hydrops fetalis. Ir Med J 1991;84:62-3
  7. Poeschmann RP. Verheijen RH. Van Dongen PW. Differential diagnosis and causes of nonimmunological hydrops fetalis: a review. Obstet Gynecol Surv 1991;46: 223-31
  8. Anandakumar C. Biswas A. Wong YC. Chia D. Annapoorna V. Arulkumaran S. Ratnam S. Management of non-immune hydrops: 8 years' experience. Ultrasound Obstet Gynecol 1996;8:196-200
  9. Moise KJ Jr. Carpenter RJ Jr. Hesketh DE. Do abnormal Starling forces cause fetal hydrops in red blood cell alloimmunization? Am J Obstet Gynecol 1992;167:907-12
  10. Ville Y. Proudler A. Abbas A. Nicolaides K. Atrial natriuretic factor concentration in normal, growth-retarded, anemic, and hydropic fetuses. Am J Obstet Gynecol 1994;171:777-83
  11. Machin GA. Hydrops revisited: literature review of 1.414 cases published in the 1980s. Am J Med Genet 1989;34:366-90
  12. Ismail KM. Martin WL. Ghosh S. Whittle MJ. Kilby MD. Etiology and outcome of hydrops fetalis. J Matern Fetal Med 2001;10:175-81
  13. Santo S. Mansour S. Thilaganathan B. Homfray T. Papageorghiou A, Calvert S, Bhide A. Prenatal diagnosis of non-immune hydrops fetalis: what do we tell the parents? Prenat Diagn 2011;31:186-95.