Journals / Düşünen Adam - Psikiyatri ve Nörolojik Bilimler Dergisi / 2013 / Cilt: 26 - Sayı: 4

Alkol aşermesinin nörobiyolojisi, genetiği ve tedavisi

Neurobiology, Genetics and Treatment of Alcohol Craving

Pages
381–387
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Other potential drugs and future choices for treating alcohol craving were also described

📌 3 Key Takeaways

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Objective & Hypothesis:Alcohol craving has increasingly been considered an important issue in alcohol use disorders in the last decade.
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Key Findings & Data:Biologic studies on alcohol craving were mainly focused on neurobiology, genetics and pharmacological treatment of this condition.
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Conclusion & Impact:Other potential drugs and future choices for treating alcohol craving were also described
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Alcohol craving has increasingly been considered an important issue in alcohol use disorders in the last decade. Biologic studies on alcohol craving were mainly focused on neurobiology, genetics and pharmacological treatment of this condition. In this report, we started from receptor systems, than we explained genetics and epigenetics of alcohol craving. At last, we described the main drugs currently used in the treatment of alcohol craving. Other potential drugs and future choices for treating alcohol craving were also described

Özet

Alkol aşermesi son 10 yılda, giderek artan bir şekilde, alkol kullanım bozukluklarında önemli bir sorun olarak kabul edilmektedir. Alkol aşermesi ile ilgili yapılan biyolojik çalışmalar, daha çok nörobiyoloji, genetik ve bu durumun farmakolojik tedavisi üzerine odaklanmaktadır. Biz bu yazımızda, reseptör sistemlerinden başlayarak, alkol aşermesinin genetiği ve epigenetiğini gözden geçirdik. Son olarak da, alkol aşermesinde kullanılan ana ilaçlardan başlayarak, alkol aşermesinde kullanılması muhtemel diğer ilaçları ve gelecekteki olası tedavi seçeneklerini açıklamaya çalıştık

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Cite This Article

ŞENGÜL, C., DİLBAZ, N. (2013). Alkol aşermesinin nörobiyolojisi, genetiği ve tedavisi. Düşünen Adam - Psikiyatri ve Nörolojik Bilimler Dergisi, Cilt: 26 - Sayı: 4, 381–387. https://ajindex.com/articles/213979

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References (15)

  1. Turkcan A. The mechanism of alcohol craving. Journal of Addiction 2002; 3:37-42. (Turkish
  2. Ulug B. Alkol ve Madde bagimliliginin norobiyolojisi In Yuksel N (Editor). Temel Psikofarmakoloji. Ankara: Tuna Matbaacilik, 2010; 367-375. (Turkish
  3. Koob GF, Volkow ND. Neurocircuitry of addiction. Neuropsychopharmacology 2010; 35:217-238
  4. Berridge KC. The debate over dopamine’s role in reward: the case for incentive salience. Psychoparmacology (Berl) 2007; 191:391-431
  5. Agrawal A, Wetherill L, Bucholz KK, Kramer J, Kuperman S, Lynskey MT, Nurnberger JI Jr, Schuckit M, Tischfield JA, Edenberg HJ, Foroud T, Bierut LJ. Genetic influences on craving for alcohol. Addict Behav 2013;38:1501-1508
  6. Addolorato G, Leggio L, Abenavoli L, Gasbarrini G; Alcoholism Treatment Study Group. Neurobiochemical and clinical aspects of craving in alcohol addiction: a review. Addict Behav 2005; 30:1209-1224
  7. Gurpunar D, Tokucoglu D. Craving of addictive substances and the dreams related with these substances. Journal of Addiction 2006; 7:38-43. (Turkish)
  8. Guveli H, Saatcioglu O. Craving in addiction. Bulletin of clinical Psychopharmacology 2008; 18:140-152. (Turkish
  9. Evren C, Celik S, Evren B, Aksoy R. Validation study of the Turkish version of the obsessive–compulsive drinking scale in male alcohol dependent inpatients. Düşünen Adam: The Journal of Psychiatry and Neuorological Sciences 2011; 24:1-12
  10. Evren C, Flannery B, Celik R, Durkaya M, Dalbudak E. Reliability and validity of Turkish version the Penn Alcohol Craving Scale (PACS) in male alcohol dependent inpatients. Journal of Addiction 2008; 9:128-134. (Turkish
  11. Evren C, Durkaya M, Celik R, Dalbudak E, Cakmak D, Flannery B. Relationship of alcohol craving with alexithymia and dissociation in male alcohol dependent inpatients. Anatolian Journal of Psychiatry 2009; 10:165-173. (Turkish
  12. Sengul C, Herken H. Dopaminerjic system and addiction. Journal of Addiction 2009; 10:155-161. (Turkish
  13. Volkow ND, Fowler JS, Wang GJ. The addicted human brain: insights from imaging studies. J Clin Invest 2003; 111;1444-1451
  14. Anton RF. Pharmacological approaches to the management of alcoholism. Journal of Clinical Psychiatry 2001; 62 (Suppl.20):11- 17
  15. Wurst FM, Rasmussen DD, Hillemacher T, Kraus T, Ramskogler K, Lesch O, Bayerlein K, Schanze A, Wilhelm J, Junghanns K, Schulte T, Dammann G, Pridzun L, Wiesbeck G, Kornhuber J, Bleich S. Alcoholism, craving, and hormones: the role of leptin, ghrelin, pro